ultrasmall superparamagnetic iron oxide
Ultrasmall superparamagnetic iron oxide nanoparticles acutely promote thrombosis and cardiac oxidative stress and DNA damage in mice
... Ultrasmall superparamagnetic iron oxide nanoparticles (USPIO, < 50 nm) have an iron oxide core that is monomer or polymer-coated/stabilized. They possess highly reactive ...
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Noninvasive monitoring of early antiangiogenic therapy response in human nasopharyngeal carcinoma xenograft model using MRI with RGD-conjugated ultrasmall superparamagnetic iron oxide nanoparticles
... context, ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles hold a great promise for use as negative magnetic resonance (MR) contrast agents with high relaxivities in terms of their ...
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Impact of surface coating and particle size on the uptake of small and ultrasmall superparamagnetic iron oxide nanoparticles by macrophages
... and ultrasmall superparamagnetic iron oxide (USPIO), alkali-treated dextran magnetite (ATDM) with particle sizes of 28 and 74 nm, and carboxymethyl dextran magnetite (CMDM) with particle sizes ...
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Bcl-2-functionalized ultrasmall superparamagnetic iron oxide nanoparticles coated with amphiphilic polymer enhance the labeling efficiency of islets for detection by magnetic resonance imaging
... higher iron (Fe) concentrations, which is beneficial for enhancing labeling efficiency; and lastly, Bcl-2 is an integral membrane protein, localized to the outer mitochondrial membrane, endoplasmic reticulum, and ...
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Ultrasmall superparamagnetic iron oxide (USPIO)-based liposomes as magnetic resonance imaging probes
... were used in the biodistribution studies: three sham mice were used as control, while the other six were separated into groups of three, either for the injection of Molday-Ion sMLs (between 170 µ L and 190 µ L, ...
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Magnetic resonance imaging of ultrasmall superparamagnetic iron oxide-labeled exosomes from stem cells: a new method to obtain labeled exosomes
... Notes: (A) Prussian blue staining of ascs to detect the presence of iron nanoparticles after UsPIO incubation. The image clearly shows a red nucleus and a blue cytoplasmic inclusion with typical perinuclear ...
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Folate-targeted polymeric micelles loaded with ultrasmall superparamagnetic iron oxide: combined small size and high MRI sensitivity
... tumor-targeting superparamagnetic iron oxide nanoparticles (SPIONs) were synthesized by loading hydrophobic SPIONs into micelles assembled from an amphiphilic block copolymer poly(ethylene glycol)- ...
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Investigating the Vascular Phenotype of Subcutaneously and Orthotopically Propagated PC3 Prostate Cancer Xenografts Using Combined Carbogen Ultrasmall Superparamagnetic Iron Oxide MRI.
... To use the combined carbogen USPIO (CUSPIO) MRI method, which uses spatial correlations in independent susceptibility imaging biomarkers, to investigate and compare the impact of tumour [r] ...
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Fabrication of Tissue-Engineered Bionic Urethra Using Cell Sheet Technology and Labeling By Ultrasmall Superparamagnetic Iron Oxide for Full-Thickness Urethral Reconstruction
... Urethral strictures remain a reconstructive challenge, due to less than satisfactory outcomes and high incidence of stricture recurrence. An “ideal” urethral reconstruction should establish similar architecture and ...
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Ultrasmall cationic superparamagnetic iron oxide nanoparticles as nontoxic and efficient MRI contrast agent and magnetic-targeting tool
... cationic ultrasmall superparamagnetic iron oxide nanoparticles caused no effects on hepatic and renal enzymes dosage as well as on leukocyte ...cationic ultrasmall ...
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Evaluation of uptake and transport of cationic and anionic ultrasmall iron oxide nanoparticles by human colon cells
... biocompatible ultrasmall superparamagnetic iron oxide nanoparticles (USPIO NPs) (iron oxide core 9–10 nm) coated with either cationic polyvinylamine (aminoPVA) or anionic oleic ...
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Mouse lymphatic endothelial cell targeted probes: anti-LYVE-1 antibody-based magnetic nanoparticles
... glycol-coated ultrasmall superparamagnetic iron oxide (LYVE-1-PEG-USPIO) nanoparticles to mouse lymphatic endothelial cells ...The iron content of the labeled cells after the Prussian ...
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<p>Ultrasmall superparamagnetic nanoparticles targeting E-selectin: synthesis and effects in mice in vitro and in vivo</p>
... Ultrasmall superparamagnetic iron oxide (USPIO) nano- particles are emerging as contrast agents for ...physiological iron (Fe)-handling ...
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Vascular and plaque imaging with ultrasmall superparamagnetic particles of iron oxide
... USPIOs can be used as a blood pool contrast agent but it is their ability to be taken up by inflammatory cells that has distinguished them [7]. Cellular uptake of USPIOs occurs through a variety of mechanisms. Phago- ...
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Enzymatic- and temperature-sensitive controlled release of ultrasmall superparamagnetic iron oxides (USPIOs)
... the iron oxide core ...of iron oxide core ...the iron oxide cores during the micellization process with PEG-PPS, rather than being displaced in a ligand- exchange ...
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Comparison of Two Ultrasmall Superparamagnetic Iron Oxides on Cytotoxicity and MR Imaging of Tumors
... To investigate the effect of USPIO on nitric oxide production in mouse macrophages, nitrite was as- sayed by the Griess reaction [27]. Briefly, the culture supernatants from the RAW264.7 cells treated with ...
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Optimizing superparamagnetic iron oxide nanoparticles as drug carriers using an in vitro blood–brain barrier model
... of superparamagnetic iron oxide nanoparticle (SPION) samples, the BBB was first examined and confirmed by an immunofluorescent stain and evaluating the transendothelial electrical ...
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Gold-functionalized magnetic nanoparticles restrict growth of <em>Pseudomonas aeruginosa</em>
... determine how nanoparticles affect host cells. An absence of toxicity is required for use of nanoparticles in future medical treatment. In this work, we assessed the effect of three types of iron oxide ...
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Magnetic nanoparticles: preparation, physical properties, and applications in biomedicine
... 1. Fluorescence techniques. Due to their small size, magnetic luminescent NPs offer a larger surface area-to-volume ratio than currently used microbe- ads, which result in a good reaction homogeneity and faster reaction ...
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<p>Strategies to enhance efficacy of SPION-labeled stem cell homing by magnetic attraction: a systemic review with meta-analysis</p>
... SPION toxicity caused by concentration, size, zeta- potential, and oxidative stress effect, the SPION is also well known to be widely used in biomedical applications, for example, magnetic resonance imaging, targeted ...
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