UNDETERMINED SIGNIFICANCE
Prevalence and type of monoclonal gammopathy of undetermined significance in an apparently healthy Nigerian population: a cross sectional study
... of Undetermined Significance (MGUS) remains the pre- ferred designation because of the recognition that this disorder can evolve into a Malignant Monoclonal Gam- ...
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The clinical relevance and management of monoclonal gammopathy of undetermined significance and related disorders: recommendations from the European Myeloma Network
... of undetermined significance is one of the most common pre-malignant ...of undetermined significance are precursor conditions of multiple myeloma; light- chain monoclonal gammopathy of ...
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Monoclonal Gammopathy of Undetermined Significance with Amyloid Deposition in the Lung and Non-Amyloid Eosinophilic Deposition in the Brain: A Case Report
... Background. Monoclonal gammopathy of undetermined significance (MGUS) is rarely complicated by amyloidosis. Case. A 66-year-old white male presented to the emergency room (ER) after an unwitnessed fall and ...
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Original Article Gene expression profiling based on microarray among monoclonal gammopathy of undetermined significance, smoldering multiple myeloma and multiple myeloma
... Abstract: Multiple myeloma (MM) and smoldering multiple myeloma (SMM) are different types of plasma cell malig- nancy which are believed to be developed from Monoclonal Gammopathy of Undetermined ...
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Altered mRNA Expression of Telomere-Associated Genes in Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma
... In this study, we explored changes in the expression of the telomere maintenance genes, TRF1, TRF2 and TANK1 in patients with monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma ...
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Hypercalcemia associated with isolated bone marrow sarcoidosis in a patient with underlying monoclonal gammopathy of undetermined significance: case report and review of literature
... Extrapulmonary manifestations of sarcoidosis are un- common. Bone marrow sarcoidosis is infrequently clinically encountered. In the few cases reported, bone marrow involvement most often occurs in the setting of systemic ...
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Evaluation of selected ultrasound features of thyroid nodules with atypia of undetermined significance/follicular lesion of undetermined significance for the Bethesda reporting system for thyroid cytology
... of undetermined signifi- cance/follicular lesion of undetermined significance” (AUS/FLUS) is estimated to lie between 5% and 15%; however, some authors suggest that the risk of malignancy in AUS/FLUS ...
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Data quality of the monoclonal gammopathy of undetermined significance diagnosis in a hospital registry
... Since 1978, the Department of Clinical Biochemistry at Aalborg University Hospital has maintained a registry of all patients in North Jutland Region with a serum M-component id[r] ...
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Central and peripheral neurological involvement in monoclonal gammopathies of undetermined significance
... Several studies have suggested a pathogenetic role of paraproteinaemias in PNS damage; 10% of patients with an idiopathic neuropathy have an associated monoclonal gammopathy, while 8% - [r] ...
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Altered Cortical Microarchitecture and Bone Metabolism in Patients with Monoclonal Gammopathy of Undetermined Significance
... Introduction Population-based studies have shown that fracture risk is increased in MGUS.1,2 Previously,3 we used high-resolution peripheral quantitative computed tomography HRpQCT imagi[r] ...
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Early alterations in stem-like/marrow-resident T cells and innate and myeloid cells in preneoplastic gammopathy
... Most human cancers are preceded by a long phase of premalignant lesions that are more common than the cancer itself. Multiple myeloma (MM) is a common hematologic malignancy wherein tumor cells grow predominantly in the ...
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Role of erythropoietin in the angiogenic activity of bone marrow endothelial cells of MGUS and multiple myeloma patients
... of undetermined significance (MGUS) and multiple myeloma (MM) patients (MGECs and MMECs, respectively) and assessed whether Epo plays a role in MGECs- and MMECs-mediated ...
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Pregnant and Postpartum Women with Atypical Glandular Cells: Follow-up and Evaluation for High-Risk HPV
... of undetermined significance (AGC) in cervicovaginal smears of pregnant and postpartum women in Duhok-Iraq; follow up these women to investigate the underlying pathology and to test for high-risk HPV ...
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Abnormal function of B lymphocytes from peripheral blood of multiple myeloma patients Lack of correlation between the number of cells potentially able to secrete immunoglobulin M and serum immunoglobulin M levels
... concentrations was seen in 42% of patients assessed at two or more time points. Of 44 patients, 52% showed a lack of correlation between the number of surface IgM+ (sIgM+) B cells and serum IgM concentration. One subset ...
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Human papillomavirus infection & anal cytological abnormalities in HIV positive men in eastern India
... of undetermined significance) ; ASCH (atypical squamous cells cannot exclude a high- grade squamous intraepithelial lesion) ; LSIL (low-grade squamous intraepithelial lesions) and HSIL (high-grade squamous ...
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HPV prevalence at enrollment and baseline results from the Carolina Women’s Care Study, a longitudinal study of HPV persistence in women of college age
... of undetermined significance (ASCUS), a low-grade squamous intraepithelial lesion (LSIL), or a high-grade squamous intraepithelial lesion (HSIL), were referred to ...
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... Management of patients with atypical squamous cells of undetermined significance (ASC-US) and atypical squamous cells cannot exclude high-grade intraepithelial lesion (ASC-H) remains controver- sial. The ...
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Frequency of rare and multi viral high-risk HPV types infection in cervical high grade squamous intraepithelial lesions in a non-native dominant middle eastern country: a polymerase chain reaction-based pilot study
... ASCUS: Atypical squamous cells of undetermined significance; CIN: Cervical intraepithelial neoplasias; FFPE: Formalin fixed paraffin embedded; HAAD: Health Authority of Abu Dhabi; HPV: H[r] ...
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Seroprevalence of Human Papillomavirus Types 6, 11, 16 and 18 in Chinese Women
... Abbreviations HPV: Human papillomavirus; VLPs: Virus-like particles; LSIL: Low-grade squamous intraepithelial lesion; ASCUS: Atypical squamous cells of undetermined significance; PE: Sph[r] ...
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Light-chain amyloidosis mimicking giant cell arteritis in a bilateral anterior ischemic optic neuropathy case
... of undetermined significance (MGUS) or smoldering myeloma, less frequently with symptomatic multiple mye- loma [2]. The vascular system is often involved by the deposition of the amyloidal-proteins, which ...
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