Upstream regulator
Adhesion glycoprotein CD44 functions as an upstream regulator of a network connecting ERK, AKT and Hippo-YAP pathways in cancer progression
... CD44 is involved in cell-cell and cell-matrix adhesion[48]. Previous findings that CD44 can activate ERK [43, 44] and AKT [7, 38-42] and attenuate Hippo signaling[45] collectively suggest that CD44 may function as a ...
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The long non-coding RNA PARROT is an upstream regulator of c-Myc and affects proliferation and translation
... and Regulator Of Translation) transcribed by RNA polymerase II and expressed at a relatively high level in a number of cell ...an upstream regulator of c-Myc affecting cellular proliferation and ...
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LesR is a novel upstream regulator that controls downstream Clp expression to modulate antibiotic HSAF biosynthesis and cell aggregation in Lysobacter enzymogenes OH11
... Next, we investigated whether Clp also serves as a downstream regulator to modulate LesR-controlled HSAF biosynthesis. To address this point, the HSAF levels from various Lysobacter strains described above were ...
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Adiporedoxin, an upstream regulator of ER oxidative folding and protein secretion in adipocytes
... mRNA expression for WT, heterozygous and Adrx null mice is shown in Figure 5A and protein expression data for the WT and knockouts are shown in Figure 5B and quantitatively analyzed in Figure 5C. The mice exhibited ...
14
Early Parity Epigenetic Footprint of FOXA1 Gene Body in Normal Breast Tissue of Iranian Women
... an upstream regulator of ER function, and the methylation status of FOXA1 gene was investigated in normal breast tissue specimens of early parous and nulliparous women, in order to identify specifically the ...
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Tumor-host signaling interaction reveals a systemic, age- dependent splenic immune influence on tumor development
... IPA upstream regulator ...the upstream regulators are either interferons (IFNγ, IFNα, IRF3, IRF7, and IFNA2) or are related to the immune system (IKBKB, CHUK, NFκB, NFκBIA, STAT3, and mir-21) ...few ...
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Serum Dickkopf 1 as a Biomarker for the Diagnosis of Hepatocellular Carcinoma
... protein with a crucial role in limb and head development in Xenopus embryos, and as an upstream regulator of T-cell factor/β-catenin that forms a negative feedback loop in the canonical [r] ...
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Inhibition of SOX2 induces cell apoptosis and G1/S arrest in Ewing’s sarcoma through the PI3K/Akt pathway
... transcriptional regulator in critical signaling pathways has been implicated in malignant pro- gressions in various human cancers [16, 19, 20, 23, ...an upstream regulator in the PI3K/Akt pathway in ...
14
Mahalakshmi Naidu, Vegi (2009): AML1-eto collaborates with the homeobox gene meis 1 in inducing acute leukemia in the mouse bone marrow transplantation model. Dissertation, LMU München: Medizinische Fakultät
... gene upstream regulator, it was analyzed whether ectopic expression of Cdx2 induced up-regulation of Hox genes in murine hematopoietic progenitor ...
136
The PDZ-binding Motif of SARS-CoV Envelope Protein Induces Cancerization and Poor Prognosis of Lung Adenocarcinoma
... MAPK1 is a member of MAP kinase family which are also called extracellular signal-regulated kinases (ERKs) and function as binding points for numerous biochemical signals [31, 32]. Former researches have indicated that ...
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MicroRNA-7 directly targets insulin-like growth factor 1 receptor to inhibit cellular growth and glucose metabolism in gliomas
... Background: Recent studies observed that altered energy metabolism has become widespread in cancer cells along with other cancer-associated traits that have been accepted as hallmarks of cancer. Akt signaling pathway is ...
6
Two component signal transduction system CBO0787/ CBO0786 represses transcription from botulinum neurotoxin promoters in Clostridium botulinum ATCC 3502
... response regulator present in the cytosol by transmission of the phosphoryl group to an N-terminal aspartate residue of the response regulator and further to the C-terminal output ...
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Characterization of Mean and Turbulent Flow over Complex Topography under various Inflow and Geometric Configurations
... far upstream end of the tunnel, however no active roughness elements were used, in order to simulate upstream conditions with ABL profile over a smooth ...
113
The Arm's Length Principle and Tacit Collusion
... the upstream firms on transfer ...two upstream firms independently and simultaneously set prices for their own affiliates and the unrelated buyers, which is followed by the downstream firms’ choice of ...
19
SuhB Is a Regulator of Multiple Virulence Genes and Essential for Pathogenesis of Pseudomonas aeruginosa
... ABSTRACT During initial colonization and chronic infection, pathogenic bacteria encounter distinct host environments. Adjust- ing gene expression accordingly is essential for the pathogenesis. Pseudomonas aeruginosa has ...
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Static voltage regulator using thyristor with transient protection implementation
... Due to the emerging technologies in the field of Power Electronics, the Load Tap Changer Voltage Regulator provides steady static voltage Regulator (SVR). The SVR has emerged as a new technology to provide ...
5
Cascaded Linear Regulator with Negative Voltage Tracking Switching Regulator
... switching regulator converts the input voltage to a voltage slightly above the desired output voltage of the two-stage ...voltage regulator steps down the output voltage of the switching regulator to ...
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Cascaded Linear Regulator with Positive Voltage Tracking Switching Regulator
... pre-tracking regulator demonstrated its ability to have the switching converter’s output follow the linear regulator’s output to improve the overall regulator’s ...pre-tracking regulator shows a range of ...
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Upstream AUGs and upstream ORFs can regulate the downstream ORF in Plasmodium falciparum
... bases upstream of the start codon, there were ~5 times more uATGs and uORFs in var genes versus other ...bases upstream of the start codon, the fold difference between var gene-associated uATGs and uORFs ...
12
Mks1p Is a Regulator of Nitrogen Catabolism Upstream of Ure2p in Saccharomyces cerevisiae
... production of Gln3p also dramatically slows growth on MKS1 and lysine biosynthesis: MKS1 was also found ammonia-containing media, but not on proline (Mine- to be identical to LYS80, a negative regulator of lysine ...
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