valproic acid
Effects of 5-aza-2ˈ-deoxycytidine and Valproic Acid on Epigenetic-modifying DNMT1 Gene Expression, Apoptosis Induction and Cell Viability in Hepatocellular Carcinoma WCH-17 cell line
... of valproic acid on proliferation, apoptosis, angiogenesis and metastasis of ovarian cancer in vitro and in ...Combined valproic acid and celecoxib treatment induced synergistic cytotoxicity ...
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Histone deacetylase inhibition in the treatment of acute myeloid leukemia: the effects of valproic acid on leukemic cells, and the clinical and experimental evidence for combining valproic acid with other antileukemic agents
... (for example through vaccination with AML-associated antigens) requires further study. The use of such an approach as a low-toxicity strategy in older patients is supported by several observations. First, primary human ...
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Antineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines
... development. Valproic acid, an 8-carbon, branched-chained fatty acid well-known as an effective antiepileptic drug [14] belongs to the Small molecular weight carboxilates ...tors, valproic ...
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The protective effects of folic acid supplementation on teratogenecity induced by the valproic acid in developing chick embryo
... folic acid supplementation on teratogenicity induced by VPA in developing chick ...of Valproic acid (VPA) with or without folic ...folic acid along with the drug in early embryogenesis period ...
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Inhibition of Enveloped Virus Infection of Cultured Cells by Valproic Acid
... Valproic acid (VPA) is a short-chain fatty acid commonly used for treatment of neurological disorders. As VPA can interfere with cellular lipid metabolism, its effect on the infection of cultured ...
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Histone Deacetylase Inhibitor Valproic Acid and Cancer [Retracted]
... [66,67]. Valproic acid is able to check cell proliferation, upregulates the androgen receptor levels and E-cadherin expression in human prostate cancer cells [68] and able to induces the neuro-endocrine ...
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Molecular dissection of the valproic acid effects on glioma cells
... agents. Valproic acid (VPA) is a histone deacetylase inhibitor that apart from its anticonvulsive effects in some retrospective studies has been suggested to lead to a superior outcome of glioblastoma ...
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Valproic Acid-Induced Hyperammonemia in the Elderly: A Review of the Literature
... “valproic acid,” and “divalproate,” “hyperammone- mia,” “hepatic encephalopathy,” “urea cycle disorder,” “liver failure,” “aged,” and ...for valproic acid level. Also, the terms ...
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THERAPEUTIC DRUG MONITORING OF TACROLIMUS AND CYCLOSPORINE, PHENYTOIN AND VALPROIC ACID
... Phenytoin, Valproic Acid in a multi- specialty ...under valproic acid treatment (5 males, 1 ...and valproic acid in renal transplant and epileptic patients ...
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INVESTIGATION OF NEUROPROTECTIVE EFFECT OF VALPROIC ACID IN DIABETIC NEUROPATHY IN STREPTOZOTOCIN INDUCED TYPE2 DIABETIC RATSNeeraj Kumar*, Suruti Rawat, Preeti KothiyalDOWNLOAD/VIEW
... of valproic acid on biochemical parameters (Serum glucose level, Lipid peroxidation, SOD & GSH and Oxidative stress) was also assessed in the brain tissue of albino wistar ...
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Development of Valproic Acid Niosomal in situ Nasal Gel Formulation for Epilepsy
... Valproic acid was a gift sample from Centaur Phar- maceuticals Ltd. Pune (India). Polyoxyethylene sorbi- tan monolaurate (Tween 20), polyoxyethylene sorbitan monopalmitate (Tween 40), polyoxyethylene sorbi- ...
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Valproic Acid Induces Endocytosis-Mediated Doxorubicin Internalization and Shows Synergistic Anti-Proliferation Effects in Hepatocellular Carcinoma Cells
... Figure 4. Combination treatment of valproic acid (VPA) and doxorubicin (DOX) synergistically augmented the autophagy of HepG2 cells. (A) Acridine orange (AO) staining was used to detect acidic vesicles in ...
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Valproic acid promotes radiosensitization in meningioma stem- like cells
... Although meningioma stem-like cells have been isolated and characterized, their therapeutic targeting remains a challenge. Meningioma sphere cells (MgSCs) with cancer stem cells properties show chemo- and radioresistance ...
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A rapid and simple procedure for monitoring valproic acid by gas chromatography
... of valproic acid from out patient’s clinic, inpatients department and intensive care unit of Poison Control Center Cairo, ASUH from November 2015 to May ...
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Lamotrigine-Valproic Acid Interaction Leading to Stevens–Johnson Syndrome
... Copyright © 2018 Marta V´azquez et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
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Pancreatitis Associated with Valproic Acid Therapy
... A review of the literature reveals no previous reports of elevated amylase and clinical signs of pancreatitis associated with valproic acid therapy. While direct evidence pinpointing VPA[r] ...
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Virtual screening and molecular dynamics simulation suggest Valproic acid Co-A could bind to SARS-CoV2 RNA depended RNA polymerase
... supports valproic acid co-A as a potential RdRp blocker. Valproic acid Co-A generates from prodrug valproic acid by one stem metabolic pathway ...receptor, valproic ...
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Valproic acid ameliorates coxsackievirus B3 induced viral myocarditis by modulating Th17/Treg imbalance
... [12]. Valproic acid (VPA), a short-chain branched fatty acid, is a clinic- ally approved HDAC inhibitor that is traditionally used in the treatment of epilepsy and has been shown to be a safe, ...
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The combination of valproic acid, all-trans retinoic acid and low-dose cytarabine as disease-stabilizing treatment in acute myeloid leukemia
... of valproic acid in the treatment of human acute myeloid leukemia (AML); a summary of the previous clinical results from studies of valproic alone, valproic acid + all-trans retinoic ...
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Effects of amoxicillin/clavulanic acid on the pharmacokinetics of valproic acid
... Abstract: Valproic acid (VPA) is mainly metabolized via glucuronide, which is hydrolyzed by β-glucuronidase and undergoes enterohepatic ...Amoxicillin/clavulanic acid (AMC) administration leads to ...
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