Var. neoformans
Genetic Relationship between Cryptococcus neoformans var neoformans Strains of Serotypes A and D
... Cryptococcus neoformans is an encapsulated yeast that can cause severe meningoencephalitis in immunocompromised pa- tients, especially those with ...C. neoformans var. neoformans (serotypes A ...
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Rapid Identification of Cryptococcus neoformans var grubii, C neoformans var neoformans, and C gattii by Use of Rapid Biochemical Tests, Differential Media, and DNA Sequencing
... neoformans var. grubii, Cryptococcus neoformans var. neoformans, and Cryptococcus gattii is imperative for facilitation of prompt treatment of cryptococcosis and for understanding the ...
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Origin of Cryptococcus neoformans var neoformans Diploid Strains
... The basidiomycetous yeast Cryptococcus neoformans is an important human fungal pathogen. Two varieties, C. neoformans var. neoformans and C. neoformans var. gattii, have been ...
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Cryptococcosis Serotypes Impact Outcome and Provide Evidence of Cryptococcus neoformans Speciation
... neoformans var. grubii into C. neoformans var. neoformans and to the origins of AD hybrids (9, ...C. neoformans as new species (C. neoformans for serotype A and the newly ...
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A Unique Chromosomal Rearrangement in the Cryptococcus neoformans var grubii Type Strain Enhances Key Phenotypes Associated with Virulence
... neoformans var. grubii (strain H99), C. neo- formans var. neoformans (strain JEC21), and ...C. neoformans var. neoformans: the introgression of ...
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Tracing Genetic Exchange and Biogeography of Cryptococcus neoformans var. grubii at the Global Population Level
... allantoate permease, which could be involved in uptake of uric acid products. The cluster of six genes unique to the VNII genomes includes a predicted transcription factor, amino acid transporter, hydrolase, ...
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Recapitulation of the Sexual Cycle of the Primary Fungal Pathogen Cryptococcus neoformans var. gattii: Implications for an Outbreak on Vancouver Island, Canada
... Cryptococcus neoformans is a human fungal pathogen that exists as three distinct varieties or sibling species: the predominantly opportunistic pathogens ...C. neoformans var. neoformans ...
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Most Cases of Cryptococcal Meningitis in HIV Uninfected Patients in Vietnam Are Due to a Distinct Amplified Fragment Length Polymorphism Defined Cluster of Cryptococcus neoformans var grubii VN1
... Cryptococcus neoformans var. neoformans control strain (VNIV), one ...C. neoformans var. grubii-C. neoformans var. neoformans hybrid (VNIII), and 100 strains from ...
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Clonal Reproduction and Limited Dispersal in an Environmental Population of Cryptococcus neoformans var gattii Isolates from Australia
... C. neoformans is determined by a single-locus, two-allele system, with the two mating types designated MAT␣ and MAT a ...C. neoformans var. neoformans, the ␣ mating type outnumbers its a ...
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Multilocus Sequence Typing Reveals Three Genetic Subpopulations of Cryptococcus neoformans var. grubii (Serotype A), Including a Unique Population in Botswana
... RYPTOCOCCUS neoformans is a pathogenic yeast that causes debilitating disease of the central ner- vous system and other organs in ...C. neoformans normally resides in the environment, where it is most ...
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Presence of α and a Mating Types in Environmental and Clinical Collections of Cryptococcus neoformans var gattii Strains from Australia
... Cryptococcus neoformans is an encapsulated, basidiomycet- ous yeast and is the causative agent of cryptococcosis, a rare but potentially serious disease of humans and animals ...C. neoformans exist, and ...
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Essential Gene Discovery in the Basidiomycete Cryptococcus neoformans for Antifungal Drug Target Prioritization
... In strain 2aPlate4C11, only one T-DNA insertion was identi- fied. The hit gene is CNAG_03105, and it encodes a hypothetical protein with no known conserved domains. This protein shares homology with the S. cerevisiae ...
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Molecular Typing of Clinical and Environmental Cryptococcus neoformans Strains Isolated in Italy
... Cryptococcus neoformans and Cryptococcus gattii have been associated with life-threatening infections in humans and other animals, while infections with other species have rarely been reported ...C. ...
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Comparison of Etest and National Committee for Clinical Laboratory Standards broth macrodilution method for azole antifungal susceptibility testing
... 2). The details of the EA between the MICs determined by the two methods are given in Table 3. The overall EA was 80%, with agreement rates among the five species of yeasts tested covering a range from 53 to 96%. The ...
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Invasion of the Central Nervous System by Cryptococcus neoformans Requires a Secreted Fungal Metalloprotease
... The inability of the mpr1⌬ strain to migrate across the brain endothelium suggests that Mpr1 promotes the transcellular cross- ing of cryptococci by facilitating an aspect of a complex series of events that include ...
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The Cryptococcus neoformans Transcriptome at the Site of Human Meningitis
... The CSF samples were part of the Duke IRB-approved database and Specimen Repository for Infectious Disease Related Studies (PR0005314) in which patients are deidentified and clinical information is limited. The HC1 ...
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Ordered Kinetochore Assembly in the Human Pathogenic Basidiomycetous Yeast Cryptococcus neoformans
... Kinetochores in C. neoformans assemble in an ordered man- ner. The appearance of nonclustered centromeres in C. neofor- mans suggests a fundamental difference in centromere dynamics between C. neoformans ...
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A Genetic Linkage Map of Cryptococcus neoformans variety neoformans Serotype D (Filobasidiella neoformans)
... Figure 1.—Genetic linkage map of C. neoformans, based on 228 RFLP markers, 63 microsatellite markers, 2 indel markers, the mating-type locus (MAT), and 7 MAT-associated PCR markers. Marker names are indicated on ...
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Microevolution of Serial Clinical Isolates of Cryptococcus neoformans var grubii and C gattii
... An independent approach to look at adaptation is to examine mutations that occur over the course of an infection and determine if any confer a selective advantage in the host. Between 10% and 20% of HIV/AIDS patients in ...
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Capsule Growth in Cryptococcus neoformans Is Coordinated with Cell Cycle Progression
... Analysis of differentially accumulated proteins in cln1 dur- ing capsule enlargement. To investigate the mechanisms by which the cln1 mutant produces larger capsules relative to the wild-type strain, we compared the ...
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