Vascular Dysfunction
Vascular Dysfunction in Leukoaraiosis
... WMH demonstrate abnormal hemodynamic parameters in a pat- tern consistent with diminished blood flow regulation and in- creased vulnerability to transient ischemia compared with NAWM. It remains to be determined whether ...
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The Role Of Putative Nox Inhibitors In Homocysteine-Induced Vascular Dysfunction
... The research on ML is limited but some work has shown its efficacy against Nox1-generated ROS; currently our lab has the only publication on ML in Hcy-impaired acetylcholine- mediated vasorelaxation. Another study showed ...
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Vascular dysfunction in monkeys with diet induced hyperhomocyst(e)inemia
... Elevated plasma homocyst(e)ine may predispose to compli- cations of vascular disease. Homocysteine alters vasomotor regulatory and anticoagulant properties of cultured vascu- lar endothelial cells, but little is ...
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Vascular dysfunction induced by elevated glucose levels in rats is mediated by vascular endothelial growth factor
... on vascular dysfunction, and ( b ) if these effects were mediated via ...and vascular permeability in granulation tissue, chambers were separately treated with 5 mM glucose plus the NOS inhibitors ...
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Pulmonary vascular dysfunction in ARDS
... pulmonary vascular resistance and mortality, whereas others found no such ...pulmonary vascular resistance and transpulmonary gradient (TPG) depend not alone on the intrinsic properties of the pulmonary ...
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α2AP regulates vascular alteration by inhibiting VEGF signaling in systemic sclerosis: the roles of α2AP in vascular dysfunction in systemic sclerosis
... Fig. 3 Effect of blocking α 2AP on the systemic sclerosis (SSc) dermal fibroblast-induced vascular dysfunction in endothelial cells (ECs). a ECs were seeded on 96-well Matrigel coated plates. ECs were ...
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Role of the haem oxygenase pathway in protection against vascular dysfunction
... coronary vascular tone was tested ex vivo using the isolated Langendorff h eart ...the vascular endothehum and smooth muscle leads to an increase in vessel ...
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Vascular endothelial growth factor A165b ameliorates outer retinal barrier and vascular dysfunction in the diabetic retina
... There are many pathways by which extravasation could occur in this model, but it is perhaps most likely to be TJ phosphorylation. This relies on the assumption that the increased solute flux is due to increased ...
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Peripheral vascular dysfunction in migraine: a review
... gauging vascular health [14]; the most commonly considered parameters are pulse wave velocity (PWV), augmentation index (AIx) and local arterial distensibility in the carotid artery or in the ...
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Silencing Of Circular RNA-ZNF609 Ameliorates Vascular Endothelial Dysfunction
... of vascular endothelial and mural cells to the angiogenic ...other vascular-related cells is critical for maintaining vascular function ...cell dysfunction would be interrupted or reversed by ...
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RhoBTB1 protects against hypertension and arterial stiffness by restraining phosphodiesterase 5 activity
... in vascular SMCs exhibit hypertension and vas- cular dysfunction but no evidence of insulin resistance or diabetes ...and vascular dysfunction caused by mutations in PPARγ depends on increased ...
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Antioxidant bilirubin works in multiple ways to reduce risk for obesity and its health complications
... cyte dysfunction that leads to metabolic syndrome once obesity has emerged, the hepatic and vascular pathology that often accompanies metabolic syndrome, the glucoli- potoxicity-induced beta-cell ...
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Association between Homa Index and Vascular Endothelial Dysfunction in Type 2 Diabetic Patients
... and vascular endothelial dysfunction, as assessed by endothelium- dependent flow-mediated dilatation (FMD) and nitroglycerin-mediated dilatation (NMD), in type 2 Diabetic (DM) ...endothelial ...
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Systemic markers of inflammation are independently associated with S100B concentration: results of an observational study in subjects with acute ischaemic stroke
... Acute ischaemic stroke is associated with a rise in systemic markers of endothelial activation, inflammation and oxidative stress [1-6]. At the site of brain injury vas- cular dysfunction, oxidative stress and ...
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Key words
... that vascular endothelial dysfunction might be the un- derlying cause of the ...endothelial dysfunction, which in turn leads to the progression and etiopathogenesis of pre-eclampsia [1, ...
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Key words
... The use of angiotensin receptor blockers re- duces the level of MCP-1. Valsartan inhibits the expression of MCP-1 and TNf-α, interleukin-6 (IL-6), interleukin-1β (IL-1β) and the infiltration of leukocytes and macrophages ...
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Rapid decline in lung function in healthy adults predicts incident excess urinary albumin excretion later in life
... endothelial dysfunction, there is limited data on its use in predicting outcomes in other vascular ...Alternatively, vascular endothelial dysfunction and lung inflammation may be two forms of ...
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Lung-specific RNA interference of coupling factor 6, a novel peptide, attenuates pulmonary arterial hypertension in rats
... on vascular cells such as ECs and vascular smooth muscle cells (VSMCs) function in a paracrine manner, supported by a previous study identified that the high local CF6 levels in tissues such as resistance ...
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Inflammation and intracranial aneurysms: mechanisms of initiation, growth, and rupture
... 86. Ali A, Yu Z, Jabbour PM, Tjoumakaris SI, Gonzalez LF, Rosenwasser RH, Koch WJ, Dumont AS. Cigarette smoke directly produces a pro‑inflammatory/matrix remodeling phenotype in cerebral vascular smooth muscle ...
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Vascular endothelial growth factor receptor inhibition enhances chronic obstructive pulmonary disease picture in mice exposed to waterpipe smoke
... markers of systemic endothelial dysfunction in mild COPD cases. These markers included microalbuminuria, impaired flow-mediated dilation, and decreased retinal vessel calibre. Kasahara et al. (2001) [20] reported ...
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