Vascular Inflammation
Kruppel like factor 15 is critical for vascular inflammation
... of vascular inflamma- tory disease states suggest that proinflammatory activation of the endothelium leads to immune cell recruitment and invest- ment within the vessel ...VSMC inflammation and vasculopathy ...
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Parietal and intravascular innate mechanisms of vascular inflammation
... Enhanced platelet activation and deregulated interac- tions with circulating leukocytes occur in the setting of small vessel vasculitides [40] and large vessel vasculitides [7], as well as in SSc [41], ...
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Restenosis after percutaneous angioplasty: the role of vascular inflammation
... of vascular disease (Jukema et al 2000; Kastrati et al 2000; Bauters et al 2001; Roguin et al ...of vascular inflammation in response to percutaneous angioplasty, and thus the occurrence of ...
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Blockade of NOX2 and STIM1 signaling limits lipopolysaccharide induced vascular inflammation
... in many cell types (19, 26). Although the NFAT pathway is responsible for cytokine production in T cell activation, its role in EC proinflammatory molecule expression and vascular inflammation has not ...
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Genetic and cellular evidence of vascular inflammation in neurofibromin deficient mice and humans
... including vascular disease, which results from neointima formation and vessel ...NF1 vascular disease remains ...between vascular and bone marrow–derived cells (BMDCs), and neurofibromin regulates ...
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Implication of free fatty acids in thrombin generation and fibrinolysis in vascular inflammation in Zucker rats and evolution with aging
... Short title: Fatty acids in thrombin generation and vascular inflammation in aging.. * These authors contributed equally to this work..[r] ...
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Dual targeting of CCR2 and CX3CR1 in an arterial injury model of vascular inflammation
... in vascular inflammation and sought to determine their combined effect in a murine arterial injury ...wall inflammation by stimulating platelet adherence, leuko- cyte recruitment, and vascular ...
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Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model
... of vascular dysfunc- tion ...chronic vascular inflammation, injury, and repair may be set in motion by elevated levels of plasma HC and other vascular risk factors, such as hypercho- ...
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MicroRNA 181b regulates NF κB–mediated vascular inflammation
... lung inflammation/injury, and ...the vascular endothelium plays a critical role in the recruitment of neutrophils and monocytes/mac- rophages as well as subsequent exacerbation of the inflammatory response ...
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Original Article miR-3646 promotes vascular inflammation and augments vascular smooth muscle cell proliferation and migration in progression of coronary artery disease by directly targeting RHOH
... Small G proteins of the Rho family are defined as major regulators of cell functions includ- ing migration, proliferation, differentiation and gene transcription [37]. Recent studies have demonstrated that abnormal ...
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Probiotic mixture VSL#3 reduce high fat diet induced vascular inflammation and atherosclerosis in ApoE−/− mice
... Atherosclerosis is recognized as an inflammatory dis- order (Tedgui and Mallat 2006), its development of is a slow progress and can be contributed by non-modifiable parameters like gender, age, and genetics; as well as ...
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Transient receptor potential canonical 5 (TRPC5) protects against pain and vascular inflammation in arthritis and joint inflammation
... We investigated the mRNA expression of TRPC5 in human synovium under normal and in fl ammatory conditions encom- passing RA and OA (see online supplementary table S1 for patient details and in fl ammation scores). We ...
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Association between carotid diameter and the advanced glycation endproduct Nε-Carboxymethyllysine (CML)
... in vascular remodeling in essential hypertension, in par- ticular as vascular remodeling is associated with inflam- mation [7,8] which reflects a major action of AGEs ...with vascular inflammatory ...
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Perivascular mast cells promote neointimal elastin deposit and suppress chronic vein graft restensosis in hyperlipidaemic mice : mast cells and vein graft remodelling
... exacerbated vascular inflammation with increased intra-plaque leukocyte infiltration, lipid uptake, vascular matrix degradation and subsequent plaque expansion and ...
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Cholinesterase: Not a robust marker of systemic low-grade inflammation in hypertension
... of vascular inflammation, high sentivity C-reactive protein (hsCRP) has been the most extensively investigated in clinical studies and has shown that baseline levels of hsCRP is a strong independent ...
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Takayasu’s disease effects on the kidneys: current perspectives
... significant renal disease is relatively common. Renovascular hypertension is the major renal problem caused by TA. The assessment of TA activity is usually challenging because vascular inflammation may ...
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The use of the tyrosine kinase inhibitor Nilotinib in Spondyloarthritis: does targeting inflammatory pathways with a treatment lead to vascular toxicity?
... in psoriasis, psoriatic arthritis and SpA [4]. Targeting the production of intracellular cytokines by synthetic small molecules such as Janus Kinase (JAK) Inhibitor (Tofacitinib ® ), Phosphodiesterase-4 (PDE-4) Inhibi- ...
5
The inflammation, vascular repair and injury responses to exercise in fit males with and without Type 1 diabetes: an observational study
... Our study provides another interesting finding that the comparable cEPCs and cECs between groups were con- comitant with ~4 fold higher TNF-α concentrations seen in our Type 1 diabetes patients. The raised ...
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Vascular involvement in rheumatic diseases: 'vascular rheumatology'
... in inflammation, angiogenesis, and atherosclerosis associated with the pathogenesis of inflam- matory rheumatic diseases, hence the term ‘vascular ...increased vascular permeability ...
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Review article DPP-4/GLP-1 axis as a potential therapeutic target in chronic stress-related vascular aging and atherosclerosis
... in vascular and adipose ...and vascular aging were observed in the aortas of stressed mice, and these changes were significantly rectified by DPP-4 inhibitor anagliptin treatment ...in vascular ...
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