vascular smooth muscle activation
The extracellular signal regulated kinase (ERK) pathway: a potential therapeutic target in hypertension
... of vascular smooth muscle cells, which can lead to a thickening of the smooth muscle layer of the blood vessels and a reduction in lumen ...increased vascular smooth ...
7
Sphingosine-1-phosphate activation of TRPC5 in vascular smooth muscle cells
... While S1P application may cause cellular responses such as changes in calcium concentration and cell migration, these responses may not solely be caused by activation of TRPC5-like channels. Xu et al. 5 utilized a ...
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Co-culture of Smooth Muscle Cells and Endothelial Cells on Porous 3D Polyurethane Scaffolds for Vascular Tissue Engineering
... and activation of PDGF 90-92 ...of vascular tissues, it has been demonstrated that the mechanical properties of the engineered vessel as well as cellular organization may be improved through dynamic ...
142
Original Article Circulating exosomes and exosomal lncRNA HIF1A-AS1 in atherosclerosis
... The activation of endotheli- al cells, migration of vascular smooth muscle cells, monocyte chemotaxis/adhesion are the main events in the processes of atherosclero- sis ...lesional ...
6
A gel-free approach in vascular smooth muscle cell proteome: perspectives for a better insight into activation
... by vascular smooth muscle cells ...the activation process and/or the bio- markers of the activated, pathological phenotype, since these factors could be the putative targets of specific, ...
9
The ATP sensitive K+ channel mediates hypotension in endotoxemia and hypoxic lactic acidosis in dog
... to activation of the K+ATP channel in vascular smooth muscle, and anaerobic metabolism with acidosis is a sufficient stimulus for channel ...
5
Immune interferon inhibits proliferation and induces 2' 5' oligoadenylate synthetase gene expression in human vascular smooth muscle cells
... stimulated with the well-defined mitogens IL 1 (from 15.3 +/- 0.7 to 6.2 +/- 0.7 dpm X 10(- 3)/24 h) or platelet-derived growth factor (PDGF) (from 18.5 +/- 1.0 to 7.3 +/- 0.7 dpm X 10(- 3)/24 h). Kinetic and nuclear ...
10
Pressure promotes DNA synthesis in rat cultured vascular smooth muscle cells
... whether activation of PLC and calcium mobilization are involved in pressure-induced DNA synthesis, production of 1,4,5-inositol trisphosphate (IP3) and intracellular Ca2+ was ...in vascular smooth ...
7
PubMedCentral-PMC5009267.pdf
... in vascular smooth muscle cells has important physiological ...During vascular injury, activated platelets or other cells pro- duce TxA2, which in turn promotes platelet activation and ...
12
Nitric oxide induces heat shock protein 70 expression in vascular smooth muscle cells via activation of heat shock factor 1
... of vascular smooth muscle cells (SMCs) via cGMP- dependent or -independent signal ...the activation of heat shock transcription fac- tor 1 (HSF1), suggesting that the response was regulated at ...
10
Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease
... pulmonary vascular remodeling during pulmonary ...pulmonary vascular remodeling in two rodent models of pulmonary ...intracellular activation of TGF-β 1 , which led to attenuated Smad2/3 ...
20
NF κB: pivotal mediator or innocent bystander in atherogenesis?
... and activation of NF-κB in cultured endothelial ...induces activation of NF- κ B in vascular smooth muscle ...increasing smooth muscle cell proliferation, leading to ...
11
Angiotensin (1-7) and Alamandine: Similarities and differences
... (NO, nitric oxide; VSMC, vascular smooth muscle cell; Red line, blocking effect; Green line, activation). 240[r] ...
19
Rapamycin inhibits vascular smooth muscle cell migration
... FKBP12 is ubiquitously expressed and highly conserved across species. However, immunoblotting with an antibody that recognizes the amino-terminus of the human, rabbit, and murine FKBP12 did not detect FKBP protein in rat ...
8
Interleukin 1 inhibits contraction of vascular smooth muscle
... Interleukin 1 has been implicated as a mediator of both systemic and local responses to infection and injury. Since systemic and local vasodilatation are hallmarks of sepsis and infection, we studied the direct effect of ...
6
Localization of distinct F2 isoprostanes in human atherosclerotic lesions
... body anti-CD68 (anti–human monocyte/macrophages) (Dakopatts, Glostrup, Denmark) (30) to characterize the phenotype of the posi- tive cells and the anti– a -smooth actin antibody (Dakopatts), which recognizes ...
8
Original Article Effects of BMSCs interactions with adventitial fibroblasts in transdifferentiation and ultrastructure processes
... and vascular adventitial fibroblasts were co-cultured by applying an identical density of 5 x 105/ml cells onto 6 ori- fice ...and vascular adventitial fibro- blasts were mixed in culture bottles in ...
9
Modification of connexin 43 expression in vascular smooth muscle
... Single and double transfections of the smooth muscle cells using the EGFP / Cx43 I pBi5 plasmid with + dox and without -dox the addition of doxycycline to the medium containing doxycycli[r] ...
295
Electrospinning of poly (ester amide) fibres for mesenchymal progenitor cell differentiation
... primary vascular smooth muscle cells (VSMC) and endothelial cells (ECs) due to their increased proliferative capacity compared to differentiated primary cells, their ability to differentiate into ...
121
Heat shock protein 27 plays a protective role in thoracic aortic dissection by promoting cell proliferation and inhibiting apoptosis
... Antibodies against HSP27 have been detected in patients with cancer and coronary diseases, although the antibody levels in patients with coronary diseases were not asso- ciated with known coronary risk factors [19]. ...
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