Vδ2+ T cells
Azathioprine therapy selectively ablates human Vδ2+ T cells in Crohn’s disease
... blood Vδ2 T cell frequency was inversely correlated with treatment duration (Figure ...in Vδ2 T cell frequency after initiating treatment (Figure ...of Vδ2 T cells is ...
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Different Roles of the CD2 and LFA-1 T-Cell Co-receptors for Regulating Cytotoxic, Proliferative, and Cytokine Responses of Human Vγ9/Vδ2 T Cells
... 2 T-cell clones indicate that the blocking of the CD2 signal important for the DNA syn- thetic and cytokine responses does not influence to the process of antigen-induced TCR downreg- ulation in these ...
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Expansions of IFN γ producing Gamma delta T cells in patients with asymptomatic persistent hepatitis B virus infection
... + T cells from patients with acute HBV infection predominantly express memory T cell phenotypes suggesting that they are also actively involved in immunity against HBV [52, ...IFN-γ-expressing ...
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Reduced pro inflammatory profile of γδT cells in pregnant patients with rheumatoid arthritis
... Vδ1 cells [8, ...and Vδ2 cells and the use of different sampling ...reduced Vδ2/Vδ1 ratios during the third trimester of pregnancy, which were due to a slight pregnancy-related reduction of ...
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Peripheral blood T-cell signatures from high-resolution immune phenotyping of γδ and αβ T-cells in younger and older subjects in the Berlin Aging Study II
... γδ T-cell memory phenotype only the expression of CD27 and CD28 was considered, as these cells were too low in abun- dance for further ...CD8+ Vδ2+ T-cells for an analysis of the memory ...
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Phenotypic and functional heterogeneity of peripheral γδ T cells in pulmonary TB and HIV patients in Addis Ababa, Ethiopia
... the Vδ2 subset as well as reduced IFNγ production in response to phos- phoantigen (IPP) stimulation, a finding observed in other studies [26, ...these cells could be dir- ect infection and destruction by ...
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Antibacterial effect of human Vγ2Vδ2 T cells in vivo
... Vγ2Vδ2 T cell–specific antigen- pretreated PBMC had 3-fold higher levels of serum IFN- γ 17 hours postinfection with ...2 T cell–specific antigen-pretreated PBMC that were first depleted of Vδ2 ...
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Functional studies on human γδ T cells and their interactions with dendritic cells and B cells
... γδ T cells have attracted interest as immunotherapeutic agents owing to their ability to respond rapidly when faced with a wide array of pathogens or transformed cells, without the requirement for ...
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Vδ2+ and α/ß T cells show divergent trajectories during human aging
... main T cell component, α/β T cells, few studies concentrate on the impact of age on γ/δ T cells’ ...immunity. Vδ2+ are the main component of γ/δ while Vδ1+ T cells ...
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Original Article Changes of peripheral blood Vδ1 T cells in patients with atherosclerotic cerebral infarction
... and Vδ2 T cells (mainly distributed in peripheral blood) [24, ...Vδ1 T cells and Vδ2 T cells have different functions, Vδ2 T cells are mainly ...
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Vγ9/Vδ2 T lymphocytes in Italian patients with Behçet's disease evidence for expansion, and tumour necrosis factor receptor II and interleukin 12 receptor β1 expression in active disease
... γ/δ T lymphocytes with phenotype V γ 9/V δ 2 in Italian patients with active and inac- tive Behçet’s ...δ T cells, V γ 9/V δ 2 T cells represent the majority of peripheral blood ...
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Phenotype and functional changes of Vγ9/Vδ2 T lymphocytes in Behçet's disease and the effect of infliximab on Vγ9/Vδ2 T cell expansion, activation and cytotoxicity
... Vγ9/Vδ2 T cells, PBMCs were cultured for 10 days in medium alone or in the presence of 0,5 mM Dimethylallyl pyrophosphate (DMAPP, Sigma, St ...days, cells were washed three times in medium, ...
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Longitudinal analysis of gamma delta T cell subsets during malaria infections in Malian adults
... γδ T cells was dominated by Vδ2− γδ T cells, which were higher than Vδ2+ γδ T cells in the majority of the volunteers in this ...γδ T cell sub- sets are the ...
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Universal CARs, universal T cells, and universal CAR T cells
... for T cells to react to allogeneic antigens and mediate GVHD ...alloreactive T cells and facilitate the engraftment of third-party CAR T cells, CD52 gene in the CAR T ...
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T cells in rheumatoid arthritis
... of T cells in chronic immune activation comes from the analysis of RA synovial biopsies ...of T cells, B cells, macrophages, and dendritic cells (about 50%); clusters of lymphoid ...
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Engineering CAR-T cells
... for T cell activation. Three different receptor types including the T-cell antigen receptors, cytokine receptors and co- stimulatory receptors are included in this ...of T cells and avoid ...
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Regulatory T cells induced by B cells: a novel subpopulation of regulatory T cells
... regulatory T cells, which named Treg-of- B cells by our group, without additional cytokines or molecules [50, ...B cells and naïve splenic CD4 + CD25 - T cells formed a stable ...
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Alloimmune T cells in transplantation
... lated T cell ...responder cells drawn from the same volunteer up to a year apart ...of T cells from a later blood ...unstimulated T cell populations is especially important for drawing ...
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T cells in myositis
... amplifying/sustaining T-cell traffi c to sites of infl ...B cells, plasma cells, and immunoglobulin sequences that plasma cell diff erentiation can take place in this location ...
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Signatures of immune reprogramming in anti-CD52 therapy of MS: markers for risk stratification and treatment response
... endpoint will be used (Wilcoxon signed-rank test, Stu- dent’s t-test for paired samples, Sign-Test). In order to compare more than two successive measurements, the preferred methods of statistical analysis are ...
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