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Ventral forebrain patterning during murine development

Dopaminergic neuronal cluster size is determined during early forebrain patterning

Dopaminergic neuronal cluster size is determined during early forebrain patterning

... plate patterning signals on the terminal differentiation and configuration of neuronal subtypes in the ...in development at which these neurons become postmitotic, as well as the developmental stage ...

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TGFβ-signaling and FOXG1-expression are a hallmark of astrocyte lineage diversity in the murine ventral and dorsal forebrain

TGFβ-signaling and FOXG1-expression are a hallmark of astrocyte lineage diversity in the murine ventral and dorsal forebrain

... Astrocyte heterogeneity might originate from diverged development and/or depend on regional localization ( Martín- López et al., 2013 ; Ramos, 2016 ). Diversification of neural stem cell progeny as observed within ...

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Mechanisms of patterning and neurogenesis in the zebrafish forebrain

Mechanisms of patterning and neurogenesis in the zebrafish forebrain

... upon during later ...in development, it too has well defined proliferative domains untü 5days ...the ventral telencephalon occurs at two adjacent areas, the ventricular and subventricular ...

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Patterning of the vertebrate ventral spinal cord

Patterning of the vertebrate ventral spinal cord

... constructed during embryonic development would provide a fascinating insight into these processes as well as greater understanding of CNS ...work. Development, in its true sense, spans the lifetime ...

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Patterning of the vertebrate ventral spinal cord

Patterning of the vertebrate ventral spinal cord

... constructed during embryonic development would provide a fascinating insight into these processes as well as greater understanding of CNS ...work. Development, in its true sense, spans the lifetime ...

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Conserved pattern of tangential neuronal migration during forebrain development

Conserved pattern of tangential neuronal migration during forebrain development

... Changes in these processes might have driven the evolution of the forebrain in vertebrates. GABAergic neurons originate from the ganglionic eminence in mammals and migrate tangentially to the cortex. We are ...

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Temporal requirement for hedgehog signaling in ventral telencephalic patterning

Temporal requirement for hedgehog signaling in ventral telencephalic patterning

... brain development, including growth, the establishment of both dorsal and ventral midline patterning and the generation of specific cell types such as oligodendrocytes and ...when during ...

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The iron exporter ferroportin 1 is essential for development of the mouse embryo, forebrain patterning and neural tube closure

The iron exporter ferroportin 1 is essential for development of the mouse embryo, forebrain patterning and neural tube closure

... Furthermore, clinical trials suggest that peri-conception vitamin supplementation that includes iron in addition to folic acid can lower the risk of NTDs further than folic acid supplementation alone (for a review, see ...

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Genetic interplay between the transcription factors Sp8 and Emx2 in the patterning of the forebrain

Genetic interplay between the transcription factors Sp8 and Emx2 in the patterning of the forebrain

... functional patterning of the developing telencephalon along the anteroposterior axis by modulating the expression gradients of Emx2 and ...of ventral cell identity in the septum and medial ganglionic ...

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A homeodomain feedback circuit underlies step function interpretation of a Shh morphogen gradient during ventral neural patterning

A homeodomain feedback circuit underlies step function interpretation of a Shh morphogen gradient during ventral neural patterning

... Ferri et al., 2007). It is also feasible that Nkx2.1 influences Shh signaling in the ventral forebrain (Sussel et al., 1999), in a fashion similar to Nkx2.2 and Nkx2.9. Importantly, our findings establish ...

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belladonna/(lhx2) is required for neural patterning and midline
axon guidance in the zebrafish forebrain

belladonna/(lhx2) is required for neural patterning and midline axon guidance in the zebrafish forebrain

... the forebrain (Fig. 1). This suggests that patterning defects may underlie axon guidance defects in the telencephalon, and shows that Lhx2 is required for normal development of this ...just ...

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Spatiotemporal patterning of EpCAM in murine embryonic differentiation

Spatiotemporal patterning of EpCAM in murine embryonic differentiation

... Varner and Taber, 2012). In this respect, the heart develops from mesoderm early in embryonic differentiation. Cardiac progenitors locate in the lateral plate mesoderm and maintain close contact with the underlying ...

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Dlx3 is expressed in the ventral forebrain of chicken embryos: implications for the evolution of the Dlx gene family

Dlx3 is expressed in the ventral forebrain of chicken embryos: implications for the evolution of the Dlx gene family

... the forebrain, were lost from the Dlx3/4 bigene cluster prior to the divergence of tetrapods from ...the forebrain of chicken embryos; this constitutes the first documented evidence of expression of either ...

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Fox (forkhead) genes are involved in the dorso ventral patterning of the Xenopus mesoderm

Fox (forkhead) genes are involved in the dorso ventral patterning of the Xenopus mesoderm

... Discussion The molecular analysis of pattern formation and lineage speci- fication has experienced major growth during the last two decades. This was partially due to the discovery that many genes controlling ...

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Effects of follistatin and BMP4 proteins on early dorso ventral patterning in chick

Effects of follistatin and BMP4 proteins on early dorso ventral patterning in chick

... retreat during dorsalisation, from a near ubiquitous distribution in early gastrula meso- and ...this patterning might also be largely independent of true growth, the early BMP4 expression evolves similarly ...

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Dorsal Ventral Patterning and Gene Regulation in the Early Embryo of Drosophila melanogaster

Dorsal Ventral Patterning and Gene Regulation in the Early Embryo of Drosophila melanogaster

... of development neuroblasts develop a unique identity based on where they are located and differentiate into specialized neuroblast ...in patterning the dorsal-ventral axis of the neurogenic ...the ...

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dTcf antagonises Wingless signalling during the development and patterning of the wing in Drosophila

dTcf antagonises Wingless signalling during the development and patterning of the wing in Drosophila

... one ventral, separated by a neurogenic region, the wing ...margin during the third larval ...steps during wing development we would expect that interference with Wingless signalling would have ...

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Uncoupling of complex regulatory patterning during evolution of larval development in echinoderms

Uncoupling of complex regulatory patterning during evolution of larval development in echinoderms

... Here we examine the expression of regulatory gene orthologs that have known or suspected roles in pat- terning the axial neuroectoderm of many protostome and deuterostome embryos within the indirectly devel- oping sea ...

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Dorsal ventral patterning in amphioxus: current understanding, unresolved issues, and future directions

Dorsal ventral patterning in amphioxus: current understanding, unresolved issues, and future directions

... However, many issues are not well understood and will require further investigations. The interactions between Nodal, Vg1, and Lefty appear to shape the activity of Smad2/3-mediated signaling, but it remains unclear ...

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A role for Shh and Bmp4 in regulating the dorsal-ventral patterning of the developing pharyngeal region

A role for Shh and Bmp4 in regulating the dorsal-ventral patterning of the developing pharyngeal region

... death during the earlier stages of organogenesis (Günther et ...proper development of the thymus, thyroid, parathyroid, and bones of the facial region (Berge et ...dorsoventral patterning of these ...

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