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Vertical supranuclear gaze palsy

MR parkinsonism index predicts vertical supranuclear gaze palsy in patients with PSP–parkinsonism

MR parkinsonism index predicts vertical supranuclear gaze palsy in patients with PSP–parkinsonism

... Objective: To identify a biomarker for predicting the appearance of vertical supranuclear gaze palsy (VSGP) in patients affected by progressive supranuclear palsy–parkinsonism ...

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Concomitant progressive supranuclear palsy and chronic traumatic encephalopathy in a boxer

Concomitant progressive supranuclear palsy and chronic traumatic encephalopathy in a boxer

... We report the case of a 75-year-old ex-professional boxer who developed diplopia and eye movement abnormalities in his 60 ’ s followed by memory impairment, low mood and recurrent falls. Examination shortly before death ...

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A Fully Automated, Atlas Based Approach for Superior Cerebellar Peduncle Evaluation in Progressive Supranuclear Palsy Phenotypes

A Fully Automated, Atlas Based Approach for Superior Cerebellar Peduncle Evaluation in Progressive Supranuclear Palsy Phenotypes

... ism (PSP-P), which is characterized by an asymmetric onset, rest- ing tremor, poor response to levodopa, and PSP-RS, in which early falls and vertical supranuclear gaze palsy occur earlier ...

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Spatial patterns of the tau pathology in progressive supranuclear palsy

Spatial patterns of the tau pathology in progressive supranuclear palsy

... patients, vertical supranuclear gaze palsy being the most consistent ...exhibited supranuclear gaze palsy, and EN were mainly absent in the cingulate gyrus and ...

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Communication impairments in people with progressive supranuclear palsy: a tutorial

Communication impairments in people with progressive supranuclear palsy: a tutorial

... either vertical supranuclear gaze palsy or both slowing of vertical saccades and prominent postural instability with falls in the first year of disease onset, and (4) no evidence of ...

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A comparison of visual problems in the parkinsonian syndromes

A comparison of visual problems in the parkinsonian syndromes

... progressive supranuclear palsy (PSP), dementia with Lewy bodies (DLB), multiple system atrophy (MSA), and corticobasal degeneration ...and vertical supranuclear gaze palsy may be ...

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How to spot ocular abnormalities in progressive supranuclear palsy? A practical review

How to spot ocular abnormalities in progressive supranuclear palsy? A practical review

... and vertical supra- nuclear gaze palsy), ‘round the houses’ sign, decreased blink rate, blepharospasm, and apraxia of eyelid opening, were selected based on their prevalence, distinctive fea- tures, ...

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Perk Genetic Variation and Function in Progressive Supranuclear Palsy

Perk Genetic Variation and Function in Progressive Supranuclear Palsy

... Progressive supranuclear palsy (PSP) is a late-onset neurodegenerative movement disorder clinically characterized by vertical gaze palsy, poor balance and frequent falls, as well as ...

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Loss of insight in frontotemporal dementia, corticobasal degeneration and progressive supranuclear palsy

Loss of insight in frontotemporal dementia, corticobasal degeneration and progressive supranuclear palsy

... Frontotemporal dementia shares many clinical, radio- logical and pathological features with the atypical sporadic parkinsonian movement disorders known as corticobasal degeneration (CBD) and progressive ...

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An autopsy-confirmed case of progressive supranuclear palsy with predominant postural instability

An autopsy-confirmed case of progressive supranuclear palsy with predominant postural instability

... and supranuclear gaze palsy represent the key symptoms of Richardson ’ s syndrome, the most frequent clinical manifestation of progressive supranuclear palsy ...of vertical ...

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A case of atypical progressive supranuclear palsy

A case of atypical progressive supranuclear palsy

... Results: Testing revealed a moderate global cognitive deficit (Mini−Mental State Examination test score =20), low memory test scores (story recall, Rey’s 15-word Immediate and Delayed Recall), and poor phonemic and ...

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Finding a new therapeutic approach for no option Parkinsonisms: mesenchymal stromal cells for progressive supranuclear palsy

Finding a new therapeutic approach for no option Parkinsonisms: mesenchymal stromal cells for progressive supranuclear palsy

... The first patient enrolled was a male who noticed motor impairment in his right arm at the age of 52. Diagnosis of PSP was made two years after the onset of symptoms, when gait difficulty, instability with falls, ...

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Pearls & Oy-sters: Ocular motor abnormalities in bilateral paramedian thalamic stroke

Pearls & Oy-sters: Ocular motor abnormalities in bilateral paramedian thalamic stroke

... bined vertical gaze palsy and bilateral INO have been poorly described in the ...the vertical gaze palsy and bilateral INO, which may represent bilateral 3rd nerve ...

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Rotigotine is safe and efficacious in Atypical Parkinsonism Syndromes induced by both a-synucleinopathy and tauopathy

Rotigotine is safe and efficacious in Atypical Parkinsonism Syndromes induced by both a-synucleinopathy and tauopathy

... Fifty-one subjects with a diagnosis of APS were treated with transdermal RTG. The diagnoses were: Parkinson’s disease with dementia, multiple system atrophy Parkinsonian type, multiple system atrophy cerebellar type, ...

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Neuroimaging-pathological correlations of [18F]THK5351 PET in progressive supranuclear palsy

Neuroimaging-pathological correlations of [18F]THK5351 PET in progressive supranuclear palsy

... been considered potentially useful for antemortem as- sessment of non-AD tauopathies, such as progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), and some variants of frontotemporal lobar ...

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Cerebral hypometabolism in progressive supranuclear palsy studied with positron emission tomography

Cerebral hypometabolism in progressive supranuclear palsy studied with positron emission tomography

... Regional cerebral cortical metabolic rates for glucose in the left hemisphere Aand in the right hemisphere B in patients with progressive supranuclear palsy PSPI expressedas a ratio to t[r] ...

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Tau burden and the functional connectome in Alzheimer's disease and progressive supranuclear palsy

Tau burden and the functional connectome in Alzheimer's disease and progressive supranuclear palsy

... Alzheimer’s disease and progressive supranuclear palsy (PSP) represent neurodegenerative tauopathies with predominantly cortical versus subcortical disease burden. In Alzheimer’s disease, neuropathology and ...

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Cognitive impairment in patients with multiple system atrophy and progressive supranuclear palsy

Cognitive impairment in patients with multiple system atrophy and progressive supranuclear palsy

... progressive supranuclear palsy occurred in five cases, while in 10 the final diagnosis was neither multiple system atrophy nor progressive supranuclear ...sive supranuclear palsy, ...

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Trigeminal neuralgia due to pontine infarction

Trigeminal neuralgia due to pontine infarction

... falls, supranuclear gaze palsy, axial more than appendic- ular rigidity, akinesia, and levodopa unresponsiveness; CBD-like if there were asymmetric extrapyramidal features that were unre- sponsive to ...

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Neuropsychiatric disturbances in atypical parkinsonian disorders

Neuropsychiatric disturbances in atypical parkinsonian disorders

... progressive supranuclear palsy; BDi, Beck Depression inventory; HAMD, Hamilton Rating Scale Depression; BPRS, brief psychiatric rating scale; SF36, Short Form (36) Health Survey; MSA-C, multiple system ...

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