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viral life cycle

The Vpr protein from HIV 1: distinct roles along the viral life cycle

The Vpr protein from HIV 1: distinct roles along the viral life cycle

... the viral DNA at least associated with inte- grase, and many recent studies have confirmed that Vpr is also an integral component of this complex (for reviews, see ...the viral complex uses the cyto- ...

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The Hepatitis E Virus Capsid C-Terminal Region Is Essential for the Viral Life Cycle: Implication for Viral Genome Encapsidation and Particle Stabilization

The Hepatitis E Virus Capsid C-Terminal Region Is Essential for the Viral Life Cycle: Implication for Viral Genome Encapsidation and Particle Stabilization

... H epatitis E virus (HEV) is responsible for acute and enterically transmitted hepatitis in the developing world (1). Before the establishment of high-efficiency HEV cell culture systems (2), in vitro generation of HEV ...

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Hepatitis B virus X protein is not central to the viral life cycle in vitro.

Hepatitis B virus X protein is not central to the viral life cycle in vitro.

... Naturally occurring missense mutation in the Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest To exclude a pX-like contribution of HuH-7 hepatoma cells to viral gene exp[r] ...

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PubMedCentral-PMC5618027.pdf

PubMedCentral-PMC5618027.pdf

... the viral life cycle ...cells, viral gene expression is regulated by the early promoter, which is located adjacent to the E6 ORF in the upstream regulatory region (URR) and is referred to as ...

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Effects of HIV-1 protease on cellular functions and their potential applications in antiretroviral therapy

Effects of HIV-1 protease on cellular functions and their potential applications in antiretroviral therapy

... the viral particle; RT inhibitors prevent conversion of viral gen- omic RNA into viral DNA, thus stopping viral DNA in- tegration into host ...the viral life ...decrease ...

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Autographa californica Multiple Nucleopolyhedrovirus ORF11 Is Essential for Budded-Virus Production and Occlusion-Derived-Virus Envelopment

Autographa californica Multiple Nucleopolyhedrovirus ORF11 Is Essential for Budded-Virus Production and Occlusion-Derived-Virus Envelopment

... restricted to the initially transfected cells. This phenotype was fur- ther confirmed by BV titration and Western blot assays. In addi- tion, the qPCR analysis results revealed that ac11 is not essential for DNA ...

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A Conserved Proline between Domains II and III of Hepatitis C Virus NS5A Influences both RNA Replication and Virus Assembly

A Conserved Proline between Domains II and III of Hepatitis C Virus NS5A Influences both RNA Replication and Virus Assembly

... the viral life cycle, we have undertaken a detailed mutagenic analysis of these proline residues in the context of both genotype 1b ...HCV life cycle; however, they also caution against ...

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Human Annexin A6 Interacts with Influenza A Virus Protein M2 and Negatively Modulates Infection

Human Annexin A6 Interacts with Influenza A Virus Protein M2 and Negatively Modulates Infection

... the viral life cycle or viral gene ...virus life cycle is regulated by the modulation of AnxA6 expression, we performed a comprehensive and system- atic dissection of the ...

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The Viral Gene ORF79 Encodes a Repressor Regulating Induction of the Lytic Life Cycle in the Haloalkaliphilic Virus ϕCh1

The Viral Gene ORF79 Encodes a Repressor Regulating Induction of the Lytic Life Cycle in the Haloalkaliphilic Virus ϕCh1

... Protein E was detected in the cell lysate 24 h earlier in the ORF79 disruption strain than in the wild-type strain (Fig. 4B). This time period corresponded to the earlier onset of lysis in the mutant strain compared to ...

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The RNA Helicase and Nucleotide Triphosphatase Activities of the Bovine Viral Diarrhea Virus NS3 Protein Are Essential for Viral Replication

The RNA Helicase and Nucleotide Triphosphatase Activities of the Bovine Viral Diarrhea Virus NS3 Protein Are Essential for Viral Replication

... the viral life cycle, the precise role of the helicase/NTPase in virus replication or whether it is essential for virus replication is still ...the viral life cycle, deletion and ...

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Nucleic Acid Binding by Mason-Pfizer Monkey Virus CA Promotes Virus Assembly and Genome Packaging

Nucleic Acid Binding by Mason-Pfizer Monkey Virus CA Promotes Virus Assembly and Genome Packaging

... the viral RNA are required for genome ...of viral genomic RNA into Gag particles, and this function could be linked to changes in nuclear ...the viral life ...

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Identification of a G2 Arrest Domain in the E1∧E4 Protein of Human Papillomavirus Type 16

Identification of a G2 Arrest Domain in the E1∧E4 Protein of Human Papillomavirus Type 16

... vegetative viral DNA amplification, prior to the expression of the viral structural proteins (10, ...with viral genome amplification, which takes place in the nucleus, 16E1 ∧ E4 has a diffuse and ...

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DNA Replication of Human Papillomavirus Type 31 Is Modulated by Elements of the Upstream Regulatory Region That Lie 5′ of the Minimal Origin

DNA Replication of Human Papillomavirus Type 31 Is Modulated by Elements of the Upstream Regulatory Region That Lie 5′ of the Minimal Origin

... The viral replication factors E1 and E2 of papillomaviruses are necessary and sufficient to replicate plasmids containing the minimal origin of DNA replication in transient ...the viral life ...

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A phenotypic host range alteration determines RD114 virus restriction in feline embryonic cells.

A phenotypic host range alteration determines RD114 virus restriction in feline embryonic cells.

... We compared various stages of the viral life cycle in restricted cells with the behavior of RD114 in the permissive G355 cell line and contrasted both to the behavior of feline leukemia [r] ...

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Anacker_unc_0153D_16442.pdf

Anacker_unc_0153D_16442.pdf

... productive viral replication, but not episomal ...of viral replication upon differentiation, suggesting that productive replication may occur through a mechanism dependent on ...the viral life ...

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p63 Is Necessary for the Activation of Human Papillomavirus Late Viral Functions upon Epithelial Differentiation

p63 Is Necessary for the Activation of Human Papillomavirus Late Viral Functions upon Epithelial Differentiation

... the viral life cycle is E6, which is, along with E7, able to efficiently immortalize human keratinocytes ...cell cycle regulation and apoptosis (26, ...

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Direct Evidence of Lower Viral Replication Rates In Vivo in Human Immunodeficiency Virus Type 2 (HIV-2) Infection than in HIV-1 Infection

Direct Evidence of Lower Viral Replication Rates In Vivo in Human Immunodeficiency Virus Type 2 (HIV-2) Infection than in HIV-1 Infection

... plasma viral loads are lower in HIV-2 infection, suggesting that HIV-2 replication is restricted in vivo in comparison to that of ...the viral life cycle of HIV-2 have been ...total ...

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WDR5 Facilitates Human Cytomegalovirus Replication by Promoting Capsid Nuclear Egress

WDR5 Facilitates Human Cytomegalovirus Replication by Promoting Capsid Nuclear Egress

... The life cycle of HCMV proceeds within the nucleus and ...double-stranded viral genome within or at the periphery of nuclear replication compartments (NRCs) in the nucleus ...(ii) Viral ...

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Altered Proteolysis and Global Gene Expression in Hepatitis B Virus X Transgenic Mouse Liver

Altered Proteolysis and Global Gene Expression in Hepatitis B Virus X Transgenic Mouse Liver

... Hepatitis B virus (HBV) is a member of the hepadnaviridae family that includes the hepatitis viruses of the woodchuck, ground squirrel, tree squirrel, Peking duck, and heron. HBV has a fourth open reading frame, termed ...

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The Ubiquitin-Proteasome System Plays an Important Role during Various Stages of the Coronavirus Infection Cycle

The Ubiquitin-Proteasome System Plays an Important Role during Various Stages of the Coronavirus Infection Cycle

... This study has demonstrated important roles for the UPS in multiple steps of the CoV infection cycle. Although further studies are needed to elucidate the precise mechanism(s) by which the UPS facilitates CoV ...

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