Virus Maturation and Release
The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release.
... The intracytoplasmic production of virus particles charac- teristic of a wild type HIV-1 infection of monocytes-macro- phages (6, 7, 17) is reminiscent of the vpuDEL-1 infection of T cel[r] ...
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Obstruction of Dengue Virus Maturation by Fab Fragments of the 2H2 Antibody
... dengue virus and might therefore be a useful tool for investigating the conformational change that occurs when the immature virus enters an acidic ...dengue virus maturation, spiky, immature, ...
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Nelfinavir Inhibits Maturation and Export of Herpes Simplex Virus 1
... We confirmed that NFV treatment is associated with a ⬎90% reduction in infectious HSV production, as originally reported by others (17). In that earlier report, the nature of antiviral action was not investigated. In the ...
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Study of herpes simplex virus maturation during a synchronous wave of assembly.
... to release it as a synchronous ...pseudorabies virus capsid assembly (16, ...following release of the block, the virus rapidly and efficiently matures to infectivity in a single synchronous ...
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The Structure of G4, the Poxvirus Disulfide Oxidoreductase Essential for Virus Maturation and Infectivity
... the release of smallpox virus into a predominantly nonimmunized population highlights the importance of understanding poxvirus ...vaccinia virus pathway, G4, which is almost identical in smallpox ...
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Infectious Bursal Disease Virus Subverts Autophagic Vacuoles To Promote Viral Maturation and Release
... decreased virus yields. In addition, the decrease in progeny virus released into the extracellular medium was greater than the decrease in intracellular viral ...progeny virus released, suggesting ...
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HIV 1 Assembly, Release and Maturation
... ABSTRACT Late steps of HIV-1 life cycle are determinant for optimal dissemination of the virus to new target cells. These steps include assembly of structural precursors, budding of the new particle and ...
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Induced Maturation of Human Immunodeficiency Virus
... proteolytic maturation occurs concomi- tant with virus release, and investigation of its dynamics is hampered by the fact that virus populations in tissue culture contain particles at all ...
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Maturation-Associated Destabilization of Hepatitis B Virus Nucleocapsid
... B virus containing the relaxed circular (RC) DNA genome can be secreted extracellu- larly as virions after envelopment with the viral surface proteins or, alternatively, can be disassembled to release RC ...
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A Proline-Rich Motif (PPPY) in the Gag Polyprotein of Mason-Pfizer Monkey Virus Plays a Maturation-Independent Role in Virion Release
... C virus) or following formation of a complete capsid (type B and type D ...to release a complete enveloped ...monkey virus (M-PMV) are phosphoproteins that are encoded in the gag gene of the ...
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Key Golgi Factors for Structural and Functional Maturation of Bunyamwera Virus
... structural maturation, we have purified and characterized the three viral forms assembled in infected cells, two intracellular intermediates and the extracellular mature ...the virus in ...
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Effects of Blocking Individual Maturation Cleavages in Murine Leukemia Virus Gag
... retroviral maturation is the conversion from the immature morphology, with a densely staining ring surrounding a relatively electron- lucent interior, to the mature form, in which the ring is absent and the center ...
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Polymorphism and Structural Maturation of Bunyamwera Virus in Golgi and Post-Golgi Compartments
... Bunyamwera virus tubes. Our study has detected another new viral structure: tubular elements built in the Golgi region, which are surrounded by a membrane frequently connected with mitochondria. Although some of ...
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In Vitro Morphology and Maturation of Lymphocystis Virus
... microscopic studies of virus particle distribution in lymphocystis tumor cells of fish.. Virus array in.[r] ...
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Steps in maturation of influenza A virus neuraminidase.
... the maturation of the influenza A virus neuraminidase (NA), using monoclonal antibodies (MAbs) with different conformational specificities against the head domains of the N8 ...in maturation of this ...
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Conformational maturation of measles virus nucleocapsid protein.
... The P-BH antiserum also immunoprecipitated a protein that comigrated with the L protein (Fig. 6A, lane d), indicating the presence of N-P as well as P-L protein complexes in the free pro[r] ...
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Cellular phosphoinositides and the maturation of bluetongue virus, a non enveloped capsid virus
... Bluetongue virus (BTV), a member of Orbivirus genus in the Reoviridae family is a double capsid virus enclosing a genome of 10 double-stranded RNA ...in virus morphogenesis in infected ...of ...
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Maturation Defects in Temperature-sensitive Mutants of Sindbis Virus
... tribution of types of viral RNA extracted from the cells infected with the three different mutant. strains of virus differed from each other and from[r] ...
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Hepatitis A Virus Suppresses Monocyte-to-Macrophage Maturation In Vitro
... morphological maturation and functional maturation of MO are markedly reduced upon chal- lenge with ...vitro maturation of MO represents a model for MAC differentiation in vivo, the results presented ...
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Human Herpesvirus 6A U14 Is Important for Virus Maturation
... initial virus genome was low (10 ...affect virus entry into host cells; however, it is highly likely that the mutant virus stock contained more virus particles than the wild-type stock, even ...
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