Voltage-dependent calcium channel
<p>Voltage-dependent calcium channel α2δ1 subunit is a specific candidate marker for identifying gastric cancer stem cells</p>
... α 2 δ 1 is a subunit of the voltage-dependent calcium channel complex expressed on cell membrane. It has been veri fi ed in other studies that α 2 δ 1 could be used to identify subpopulations ...
12
Genetic and physical mapping of the murine epilepsy locus lethargic (lh) and investigation of voltage-dependent calcium channel beta subunits in human absence seizure predisposition
... Screening genom ic libraries by PGR and radioactive hybridisation with sim ple sequence length polym orphism s (SSLPs) or sequence tagged sites (STS) from within or[r] ...
258
Expression, localisation and function of truncated forms of the voltage-dependent calcium channel alpha1b
... Figure 5.19 Optical Sections Showing Expression and Subcellular Localisation of EYFP Domain l-ll and ECFP Domain lll-IV in.. the Presence of aP-Si and Rib 202.[r] ...
289
Conversion of amylase secreting rat pancreatic AR42J cells to neuronlike cells by activin A
... free calcium concentration in response to depolarizing concentration of ...cell-type voltage-dependent calcium ...free calcium concentration, while it induced a marked elevation of free ...
12
Pharmacological and biophysical characteristics of voltage-dependent calcium channels in rat cerebellar granule neurones
... single calcium channels in cerebellar granule ...open channel probability which are prolonged in the presence of DHP agonist, have an inactivating profile and showing a high number of ...P-type ...
229
G proteins modulate invertebrate synaptic calcium channel (LCav2) differently from the classical voltage dependent regulation of mammalian Cav2 1 and Cav2 2 channels
... accessory subunits: 21 (NP_037051), 1b (NP_059042)] and sometimes G-protein subunits G1 (AAD00650) and 2 (AAB82554) harbored in mammalian expression vectors were heterologously expressed by transfection using either ...
10
Expression, characterisation and structural analysis of the putative slow voltage-dependent potassium channel minK
... potassium channel proteins directly from their native ...potassium channel genes have been cloned, the vast majority o f which encode proteins that form a superfamily o f structurally related potassium ...
289
Voltage dependent calcium channels: Subcellular subunit localisation and targeting
... the four P subunits (See Chapter 5). Why the a lC should show this distinctive pattern, or to which organelle the subunit is localised is not known. Although the a l C subunit is known to have a role in functions that ...
215
Analysis of calcium channel properties in cultured leech retzius cells by internal perfusion, voltage clamp and single channel recording
... This ensemble of properties, including high Sr2"1" conductance and voltage-dependent activation and deactivation kinetics, set Retzius cell calcium channels apart from those found in oth[r] ...
16
Calcium Channel Trafficking Blocker Gabapentin Bound to the α2δ-1 Subunit of Voltage-Gated Calcium Channel: A Computational Structural Investigation
... 14. Field, M.J.; Cox, P.J.; Stott, E.; Melrose, H.; Offord, J.; Su, T.Z.; Bramwell, S.; Corradini, L.; England, S.; Winks, J.; Kinloch, R.A.; Hendrich, J.; Dolphin, A.C.; Webb, T.; Williams, D. Identification of the ...
10
Cloning and Characterization of Alternatively Spliced Voltage-Gated Calcium Channel Subunits.
... the voltage dependence of activation, as well as a decrease in the rate of ...the voltage dependence of activation means that a stronger membrane depolarization is required to activate the channel ...
165
CALCIUM CHANNEL CURRENTS IN CULTURED PARS INTERCEREBRALIS NEUROSECRETORY CELLS OF ADULT LOCUSTA MIGRATORIA
... block voltage-operated calcium channels in vertebrate neurones (King et ...all voltage-operated calcium channels, inducing a faster current ...affect calcium channel currents of ...
6
The Caenorhabditis elegans voltage-gated calcium channel subunits UNC-2 and UNC-36 and the calcium-dependent kinase UNC-43/CaMKII regulate neuromuscular junction morphology
... present in C. elegans, and is localized to the presynaptic active zone [15]. At synapses UNC-2 regulates calcium ion entry that facilitates synaptic vesicle exocytosis [16]. It is the reduced neural transmission ...
13
Action Potentials in Rhodnius Oocytes: Repolarization is Sensitive to Potassium Channel Blockers
... These increases in overshoot and duration of APs in barium salines suggest that barium might not only permeate through calcium channels, but might also block a voltage-dependent potassiu[r] ...
14
Modulation of pulmonary vasomotor tone in the fetus and neonate
... decades, calcium-dependent (K Ca ), ATP- dependent (K ATP ), and several voltage-dependent (K V ) potassium channels have been identified on both pulmonary endothelial and vascular ...
6
18q Loss of Heterozygosity in Microsatellite Stable Colorectal Cancer is Correlated with CpG Island Methylator Phenotype-negative (CIMP-0) and Inversely with CIMP-low and CIMP-high
... Abbreviations and HUGO Gene Nomenclature Committee HGNC-approved official gene symbols used CACNA1G, calcium channel, voltage-dependent, T type alpha-1G subunit CDKN2A, cyclin-dependent [r] ...
10
Deletion of a specific exon in the voltage gated calcium channel gene cacophony disrupts locomotion in Drosophila larvae
... II voltage-gated calcium channel family, member of which act to regulate many neuronal processes, including synaptic neurotransmission at the NMJ, synaptogenesis and synaptic homeostasis, as well as ...
11
Ion channels expression and function are strongly modified in solid tumors and vascular malformations
... 21 channel families, namely: amiloride-sensitive cation channels, calcium Channels voltage-dependent, cation channels sperm associated, FXYD domain containing ion transport regulators, ...
15
Dominant-negative synthesis suppression of voltage-gated calcium channel Cav2.2 induced by truncated constructs
... biophysical properties. Furthermore, when it was coexpressed with either domain I-II or domain I, the fluorescence of green fluorescent protein (GFP)–Ca v 2.2 and expression of Ca v 2.2 protein was almost abolished. ...
10
In vitro study of the tocolytic effect of oroxylin A from Scutellaria baicalensis root
... potassium channel inhibitors, including 4-AP and glipizide, showed significant inhibi- tion of oroxylin A-induced relaxation with IC 50 values of ...potassium channel antagonists, TEA appeared more ...
7