Warfarin therapy
Characteristics of patients with thromboembolic disorders on warfarin therapy in resource limited settings
... of warfarin in developed economies has led to improved outcomes ...optimal warfarin use in order to prevent bleeding and thrombotic ...of warfarin therapy until the target value is achieved, ...
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Pharmacogenetics in warfarin therapy
... warfarin therapy. Prescribing the correct dose at the start of warfarin therapy is the most ...predicting warfarin stable ...prescribing warfarin is major bleeding, our research ...
221
Estimation of plasma levels of warfarin and 7-hydroxy warfarin by high performance liquid chromatography in patients receiving warfarin therapy
... of warfarin was ...the warfarin and it’s metabolite from plasma using isopropanol and potassium phosphate buffer (40:60) mobile ...phase. Warfarin, 7-hydroxy warfarin and carbamazepine ...
5
Pharmacogenetic, clinical and demographic factors in the management of warfarin therapy
... stable warfarin dose before OAT ...once warfarin therapy has commenced, functional assays of factors II, VII, IX and X were performed on a cohort of patients before the initiation of warfarin, ...
152
Examining warfarin underutilization rates in patients with atrial fibrillation: Detailed chart review essential to capture contraindications to warfarin therapy
... Electronic medical records were reviewed for stroke risk factors, which included baseline demographic variables and previous diagnoses of stroke/transient ischemic attack (TIA), congestive heart failure (CHF), myocardial ...
6
Warfarin Therapy: Survey of Patients Knowledge of their Drug Regimen
... for warfarin and the indication for the ...associated warfarin adverse effects, medication knowledge by age, and patients’ knowledge of medical ...to warfarin therapy, complications, and ...
5
Effects of coagulation factor VII polymorphisms on warfarin sensitivity and responsiveness in Jordanian cardiovascular patients during the initiation and maintenance phases of warfarin therapy
... The Human Research Committees at Jordan University of Science and Technology in Irbid, Jordan and the Royal Medical Services in Amman, Jordan approved this study. This study was also conducted in accordance with the ...
8
Subtherapeutic INR in a Patient on Warfarin Therapy after Discontinuation of Lomustine
... 3A4. Warfarin is a racemic mixture of R- and S- enantiomers that are metabolized differently by the CYP enzyme ...of warfarin and thus increase the concentration of ...increased warfarin effect has ...
5
Improving inpatient warfarin therapy safety using a pharmacist-managed protocol
... The impact on bleeding complications was perhaps less than expected at the outset of the project. While a supratherapeutic INR increases the risk of bleeding, other risk factors for warfarin-related haemorrhage ...
10
Patient self-management of warfarin therapy
... was likely underpowered to detect these differences. This study is subject to several limitations. First is a lack of external validity, as only 1 practice was used in patient recruitment. This is more likely to affect ...
7
A hemodialysis cohort study of protocol based anticoagulation management
... of warfarin therapy data (from 25 hemodialysis patients) in the pre-protocol timeframe, and 3308 patient-days of warfarin therapy data (from 21 hemodialysis patients) in the on-protocol ...
5
Use of warfarin in long-term care: a systematic review
... about Warfarin Use Two studies (n = 289) [27,29] explored physician atti- tudes toward warfarin prescribing using case-study ques- tionnaires targeted to physicians (Table 3), while one study (n = 91) [28] ...
33
Ximelagatran: direct thrombin inhibitor
... acute therapy of venous thromboembolism, either DVT or PE, requires initial anticoagulation with parenteral heparin and subsequently vitamin K antagonists in most ...with warfarin usually initiated 24–48 ...
10
Practice Parameter: Recurrent stroke with patent foramen ovale and atrial septal aneurysm: [RETIRED]Report of the Quality Standards Subcommittee of the American Academy of Neurology*
... We chose to limit our analysis to RCT and pro- spective cohort studies for a number of reasons. First, retrospective studies for this type of clinical question have tremendous potential for bias that sig- nificantly ...
10
Vol 8, No 4 (2016)
... in warfarin therapy among white ethnicities, but only 20% among Africans descents, this might be due to the reduced frequencies of these alleles as mentioned earlier 14 ...
12
Percutaneous left atrial appendage closure devices: safety, efficacy, and clinical utility
... long-term warfarin (international normalized ratio [INR] ...with warfarin for 45 days to facili- tate device endothelialization. Warfarin was discontinued if the follow-up transesophageal ...
8
Statistical design of personalized medicine interventions: The Clarification of Optimal Anticoagulation through Genetics (COAG) trial
... personalized therapy interven- tion: to accommodate the potential differential effective- ness of genotype-guided therapy across subpopulations defined by allelic ...
9
Unmasking Acquired hemophilia B disguised in an elderly male on Warfarin treatment – a case report and literature review.
... to Warfarin therapy (Warfarin induced ...stopping Warfarin and starting sub-cutaneous Low Molecular Weight Heparin (LMWH) till detail work was ...
5
Genetic polymorphisms of patients on stable warfarin maintenance therapy in a Ghanaian population
... on warfarin therapy was 24 months [IQR: ...on warfarin therapy was marginally associated with high warfarin dose (adjusted OR = ...high warfarin dose compared to persons with ...
7
Management of acute venous thromboembolism among a cohort of patients discharged directly from the emergency department
... In this cohort of patients discharged directly from ED with a VTE, traditional therapy with a parenteral anticoagu- lant±warfarin therapy was the most used strategy (70.7%) while 27.8% of patients ...
8