White adipose tissue dysfunction and hypertension
Obesity, estrogens and adipose tissue dysfunction : implications for pulmonary arterial hypertension
... of adipose tissue to expand and store ...for adipose expansion is determined by both genetic and environmental factors and once the adipose tissue expansion limit is reached, ...
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Hysteresis of White Adipose Tissue
... in adipose tissue masses and adipose cell size, biopsies of RWAT were ...in adipose cell sizes on the same animal during the time-course of the experimental ...retroperitoneal adipose ...
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Glucotoxicity, Protein Glycation and Adipose Tissue Dysfunction
... human white adipocytes suggesting a possible role to the adipocytes differentiation ...in adipose tissue DPP4 will have a strong impact: it stimulates lipid accumulation and PPARγ expression and it ...
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Hypertrophic Obesity and Subcutaneous Adipose Tissue Dysfunction
... Adipose tissue can be divided into two major types: white adipose tissue (WAT) and brown adipose tissue (BAT), both of which have different physiological roles ascribed to ...
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Hypoxia and adipose tissue function and dysfunction in obesity
... more tissue-specific than HIF-1, and it is suggested that it may respond to different levels of O 2 ...in adipose tissue of obese mice (72, ...in adipose tissue show reduced weight gain ...
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Hypertrophic Obesity and Subcutaneous Adipose Tissue Dysfunction
... Adipose tissue can be divided into two major types: white adipose tissue (WAT) and brown adipose tissue (BAT), both of which have different physiological roles ascribed to ...
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Hypoxia-inducible factor 3A gene expression and methylation in adipose tissue is related to adipose tissue dysfunction
... DNA methylation is the predominant epigenetic modification in vertebrates (87). A methyl group from S-adenosine methionine is attached to the 5’ position of a cytosine residue within a cytosine-phosphate-guanine (CpG) ...
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NPC1 in human white adipose tissue and obesity
... Declaration of Helsinki and approved by the Regional Eth- ics committee in Stockholm, Sweden. All subjects were healthy except for obesity and were investigated in the morning after a night ’ s fast. For those patients ...
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Cold induced changes in gene expression in brown adipose tissue, white adipose tissue and liver
... Abstract Cold exposure imposes a metabolic challenge to mammals that is met by a coordinated response in different tissues to prevent hypothermia. This study reports a transcriptomic analysis in brown adipose ...
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Differences in the Inflammatory Response of White Adipose Tissue and Adipose-Derived Stem Cells
... fat tissue is straightforward, the therapeutic use of isolated stem cells is controversial and, to date, not clinically approved in most ...for tissue repair, and it was proposed that they secrete factors ...
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Exercise induced adaptations to white and brown adipose tissue
... that adipose tissue plays an important role as a major endocrine organ that can be stimulated by ...to adipose tissue and their effect on metabolic ...to adipose tissue with ...
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Hormonal factors in the control of the browning of white adipose tissue
... including adipose tissues through the specific bile acid receptors farnesoid X receptor-α (FXRα), a nuclear receptor activated by bile acids, and the G-protein- coupled receptor ...
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Direct effects of leptin on brown and white adipose tissue
... in white fat pads ex ...reduces tissue triglyceride stores compared with pair-fed controls, already suggesting a role for leptin be- yond its appetite-reducing properties (25, ...in white fat pads ...
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Regulatory microRNAs in Brown, Brite and White Adipose Tissue
... 223. Yao, F.; Yu, Y.; Feng, L.; Li, J.; Zhang, M.; Lan, X.; Yan, X.; Liu, Y.; Guan, F.; Zhang, M.; et al. Adipogenic miR-27a in adipose tissue upregulates macrophage activation via inhibiting PPARγ of ...
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Inflammation and impaired adipogenesis in human white adipose tissue
... However, upon 13-color analysis and sorting by flow cytometry, we further could not separate the two groups as there were no significant differences in SVF cell population frequencies between the groups. This was a ...
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Mechanisms of white adipose tissue progenitor differentiation and fibrosis
... contribution of non-adipocytes attached to the buoyant adipocytes. For instance, there was a marked increase in presumably dead adipocytes associated CLS in fibrotic eWAT (Fig. 5B) (17), and these plin1 negative ...
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Evaluation of macrophage plasticity in brown and white adipose tissue
... This is the author’s final, peer-reviewed manuscript as accepted for publication. The publisher-formatted version may be available through the publisher’s web site or your institution’s library. This item was retrieved ...
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The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis
... age-related dysfunction of adipocyte progenitors and metabolism, as elegantly demon- strated in mice expressing a p16INK4a promoter–driven inducible caspase-8 (INK4-ATTAC mice) ...
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Loss of ADAMTS5 enhances brown adipose tissue mass and promotes browning of white adipose tissue via CREB signaling
... Therefore, we derived progenitor cells from the SVF of the SC AT depot of both wild-type and Adamts5 / mice and stimulated their differ- entiation towards beige cells. Cells without ADAMTS5 showed an increased beige ...
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Phytochemicals as novel agents for the induction of browning in white adipose tissue
... brown adipose tis- sue that may be able to counteract the loss of function of brown fat seen in ...brown adipose tissue have not been thoroughly investi- gated alone or in combination with other ...
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