Winged-helix
The 4 kilobase promoter region of the winged helix transcription factor HNF 3alpha gene elicits transgene expression in mouse embryonic hepatic and intestinal diverticula
... Int I Dev BioI 42 741 746 (1998) Original Article The 4 kilobase promoter region of the winged helix transcription factor HNF 3a gene elicits transgene expression in mouse embryonic hepatic and intest[.] ...
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DNA binding and unwinding by Hel308 helicase requires dual functions of a winged helix domain
... a winged helix fold. This winged helix domain (WHD) has a solvent exposed putative ‘recognition’ α-helix similar to DNA or protein binding ...
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Winged Helix Transcription Factor CPCR1 Is Involved in Regulation of β-Lactam Biosynthesis in the Fungus Acremonium chrysogenum
... Winged helix transcription factors, including members of the forkhead and the RFX subclasses, are char- acteristic for the eukaryotic domains in animals and fungi but seem to be missing in ...
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Rfx6 is an Ngn3 dependent winged helix transcription factor required for pancreatic islet cell development
... The transcription factor neurogenin 3 (Neurog3 or Ngn3) controls islet cell fate specification in multipotent pancreatic progenitor cells in the mouse embryo. However, our knowledge of the genetic programs implemented by ...
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Crystal Structure of F-93 from Sulfolobus Spindle-Shaped Virus 1, a Winged-Helix DNA Binding Protein
... the winged-helix ...of helix 1, and helix ...the winged-helix motif are marked for the amber monomer (H1 through H3), and the wings and recognition helix (H3) are ...
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DNA binding and unwinding by Hel308 helicase requires dual functions of a winged helix domain
... a winged helix domain (WHD) whose function is ...alpha helix, (b) it is required indirectly for ATPase and helicase activity, through interaction with a RecA-like domain via phenylalanine residues ...
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Ligand-responsive Transcriptional Regulation by Members of the MarR Family of Winged Helix Proteins
... The MarR (multiple antibiotic resistance regulator) family of prokaryotic transcriptional regulators includes proteins critical for control of virulence factor production, bacterial response to antibiotic and oxidative ...
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The winged helix transcription factor Foxg1 facilitates retinal ganglion cell axon crossing of the ventral midline in the mouse
... To characterise this defect, we 1 used lacZ reporter transgenes to identify potential sites at which Foxg1 expression might influence the navigation of retinofugal axons; and 2 examined [r] ...
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The Yeast Heterochromatin Protein Sir3 Experienced Functional Changes in the AAA+ Domain After Gene Duplication and Subfunctionalization
... bridging helix be- tween the AAA+ and winged helix ...KlOrc1 winged helix domain plus the bridging helix was not functional (Fig- ure 8, construct ...the winged ...
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Update of human and mouse forkhead box (FOX) gene families
... The winged helix/forkhead nomenclature committee defined the FOX family as all genes/ proteins having sequence homology to the canoni- cal winged helix/forkhead DNA-binding domain; subclasses ...
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Immune-related gene signature for predicting the prognosis of head and neck squamous cell carcinoma
... DEGs: differentially expressed genes; FoxP3: forkhead/winged-helix tran- scription factor box P3; GEO: Gene Expression Omnibus; GSEA: Gene Set Enrichment Analysis; HNSCC: head and neck [r] ...
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Late-onset of immunodysregulation, polyendocrinopathy, enteropathy, x-linked syndrome (IPEX) with intractable diarrhea
... IPEX: Syndrome of immune dysregulation, polyendocrinopathy, enteropathy, X linked; T1DM: Type-1 diabetes mellitus; EGDS: Esophagogastroduodenoscopy; FKH: Forkhead/winged helix domain; mT[r] ...
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Null Mutations in the lin-31 Gene Indicate Two Functions During Caenorhabditis elegans Vulval Development
... the larvae. Larval stage was confirmed by gonad size, and VPCs the end of the RTK signaling pathway specifying vulval were spot-checked for inappropriate L2 divisions. To prevent cell fate, and sequence analysis showed ...
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Wide band RH Circular Polarized Antenna; Design and Analysis
... of helix and are mounted over a ground ...of helix and ground ...of helix are comparable to wave ...of helix is terminated with flat metal sheet which reflects waves to ...of helix ...
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Statistical shape methodology for the analysis of helices
... statistical helix model (similar in spirit to Mardia et ...the helix axis to start the iterations, and there are a large number of methods in the literature such as Rotfit described by Christopher et ...
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The Quintuple Helix innovation model: global warming as a challenge and driver for innovation
... this helix has a ‘political and legal capital’ (for example: ideas, laws, plans, politicians, ...Quintuple Helix Model can be described in the following way (see Figures 3 and 4): It is a theoretical and ...
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Investigating helix helix interactions in the transmembrane domains of membrane proteins
... Identifying helix-helix interactions and the structural determinants that drive α - helical membrane protein folding is a technically challenging problem due to their ...
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C-Terminal Region of Outer Surface Protein C Binds Borreliacidal Antibodies in Sera from Patients with Lyme Disease
... 5 helix and a small region of the ␣ 4 helix (12), and high concentrations of antibodies specific for regions ( ␣ 1 helix) near the N terminus have been observed in sera from patients with early Lyme ...
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Comparative transcriptomic analysis of a wing-dimorphic stonefly reveals candidate wing loss genes
... Late instar Z. fenestrata nymphs were collected by hand from beneath rocks in the stream at an altitude of 670 m in Lug Creek, Rock and Pillar Range, Otago, New Zealand, in July 2017. This site is just above the alpine ...
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MyoD and the regulation of myogenesis by helix loop helix proteins
... Many members of the HLH protein family, including the MyoD family of myogenic regulatory genes, have a region rich in basic amino acids that is immediately amino-terminal to the HLH doma[r] ...
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