Wnt1/ β-catenin
Original Article N1,N3-bis(3-methoxysalicylidene) diethylenetriamine induces apoptosis in colon cancer HCT-116 cells through inhibiting Wnt1/β-catenin signaling pathway
... family, Wnt1 has been reported as a proto-oncogene which has the ability to activate the Wnt/β-catenin signaling pathway ...that Wnt1 could regulate the progression of cancer beca- use it ...
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miR-140-5p regulates the odontoblastic differentiation of dental pulp stem cells via the Wnt1/β-catenin signaling pathway
... Furthermore, Wnt1, the target gene of miR-140-5p was confirmed in our study by luciferase reporter gene detection ...of Wnt1 and β-catenin, whereas the sup- pression of miR-140-5p produced the ...
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Honokiol abrogates leptin-induced tumor progression by inhibiting Wnt1-MTA1-β-catenin signaling axis in a microRNA- 34a dependent manner
... of Wnt1 is a functional target of miR-34a in dendritic cell differentiation ...that Wnt1 regulates MTA1-β-catenin axis in breast cancer cells ...of Wnt1- MTA1- β-catenin ...
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miR 34a Inhibitor May Effectively Protect against Sevoflurane Induced Hippocampal Apoptosis through the Wnt/β Catenin Pathway by Targeting Wnt1
... Materials and Methods: C57/BL6 mice (7-day-old) inhaled 2.3% sevoflurane for 2 h/day over 3 consecutive days. miR-34a ex- pression was reduced through intracerebroventricular injection with miR-34a interference ...
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<p>Effects of Wnt/β-Catenin Signal Pathway Regulated by miR-342-5p Targeting CBX2 on Proliferation, Metastasis and Invasion of Ovarian Cancer Cells</p>
... CBX2, Wnt1, β -catenin, C-myc and Cyclin D1 in SKOV3-blank group, SKOV3-NC group, SKOV3 group, OVCAR3-blank group, OVCAR3-NC group and OVCAR3 group were ...
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MicroRNA-506 inhibits tumor growth and metastasis in nasopharyngeal carcinoma through the inactivation of the Wnt/β-catenin signaling pathway by down-regulating LHX2
... LHX2, Wnt1, β-catenin, E-cadherin, Vimentin, Twist, U6 and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) were designed and synthesized by the TaKaRa Company (TaKaRa, Dalian, Liaoning, China) ...
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Original Article miR-140-5p inhibits proliferation, invasion, and promote apoptosis of non-small cell lung cancer cells through targeted inhibition of Wnt signaling pathway
... overexpressed, Wnt1 could lead to recruitment factors such as β-catenin and TCF- 4, thus triggering the expression of downstream translation related ...after Wnt1 overexpression, the ...
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Baicalein suppresses metastasis of breast cancer cells by inhibiting EMT via downregulation of SATB1 and Wnt/β-catenin pathway
... Wnt/ β -catenin pathway in a dose-dependent ...(SATB1, Wnt1, β -catenin, E-cadherin, vimentin, and SNAIL) than therapy treatment (which began ...
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Vol 29, No 3 (2019)
... of Wnt1 and double-stain immunohistochemistry performed to see melanocyte stem cells expressing ...anti β-catenin monoclonal mouse [(E-5), (Santa Cruz, catalog number sc- 7963)], UltraVision ...
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Macrophage Migration Inhibitory Factor Promotes Proliferation and Neuronal Differentiation of Neural Stem/Precursor Cells through Wnt/β-Catenin Signal Pathway
... the Wnt1 class signal into the cell via the canonical Wnt/ β -catenin ...of β-catenin, which enters the nucleus, and associates with T-cell factor/lymphoid enhanc- er-binding factor ...
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Localization of planarian β CATENIN 1 reveals multiple roles during anterior posterior regeneration and organogenesis
... of β -catenin-1 itself (Adell et ...after β -catenin-1(RNAi) depends on the time and dose of inhibition (Adell et ...Although β -CATENIN-1 is widely present in specific organs of ...
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Original Article Expression of β-catenin and axin in metaplastic breast carcinomas
... of β-catenin in 292 invasive ductal breast ...cytoplasmic β-catenin expression, and high tumor grade, positive Ki67, negative estro- gen receptor ...of β-catenin was associated ...
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IKKβ is a β-catenin kinase that regulates mesenchymal stem cell differentiation
... Adipogenic differentiation. Adipogenesis protocol of mouse cells was developed as previously described (7, 18). Briefly, 2 days after the cells were confluent, DMEM supplemented with 10% FBS, 1 μM dexametha- sone, 0.5 mM ...
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Andrographolide reduces cognitive impairment in young and mature AβPPswe/PS-1 mice
... evaluated β-catenin, which is a protein downstream of GSK-3β that is phosphorylated by GSK-3β, determining its degradation ...the β-catenin levels in slices incubated with ANDRO, suggesting a ...
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Circular RNAs Regulate Cancer Onset and Progression via Wnt/β Catenin Signaling Pathway
... Cancer remains to be a major challenge for public health providers, and is the second leading cause of death worldwide. There- fore, it is imperative to explore the mechanisms underlying cancer initiation and ...
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The Regulation of β-catenin signalling by α-catenin
... p- catenin/T cf complex: one pool is bound to a-catenin and is inactive and the other pool is a-catenin-free and ...p- catenin than SW480 cells (Figure 18a), one w ould predict that loss of a- ...
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<p>Catalpol Promotes the Proliferation and Differentiation of Osteoblasts Induced by High Glucose by Inhibiting KDM7A</p>
... Wnt/ β - catenin signaling pathway can promote osteoblast differ- entiation and ...of β -catenin causes the development of osteo- blast stagnating at an early stage, thereby leading to ...
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Original Article Distinct patterns of ALDH1A1 expression predict metastasis and poor outcome of colorectal carcinoma
... addition, β-catenin is used as a supplemental marker in the analysis to stratify the expression profiles of investigated genes in CRC patients, such as CD44, CD133, CD166, and ALDH1A1 [13, ...group, ...
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PubMedCentral-PMC5647938.pdf
... involving β -catenin, Brn2, and Tbr2, causing an expansion of the IP cell population and ASD-related aberrant social behavior (Belinson et ...GSK3 β antagonist, lithium, which activates β ...
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Role for α3 integrin in EMT and pulmonary fibrosis
... accumulation and collagen deposition. One possible source of (myo)fibroblasts is epithelial cells that undergo epithelial-mesenchymal transition (EMT), a process frequently mediated by TGF-b. In this issue of the JCI, ...
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