Wnt/β-catenin pathways
Cooperation of FGF/MEK/ERK and Wnt/β-catenin pathway regulators to promote the proliferation and pluripotency of mouse embryonic stem cells in serum- and feeder-free conditions
... and Wnt/β-catenin pathways, especially their dif- ferent functions on proliferation and pluripotency of mESCs between individual and joint regulation, was ...
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Circadian Rhythms and Energy Metabolism Reprogramming in Parkinson's Disease
... of WNT/β-catenin pathway signaling (Clevers and Nusse, 2012; Inestrosa, Montecinos- Oliva, and Fuenzalida, 2012; Rosi et ...the WNT signaling (Semënov, Zhang, and He, 2008), binds to LRP5/6 ...
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miR-185 suppresses progression of Ewing’s sarcoma via inhibiting the PI3K/AKT and Wnt/β-catenin pathways
... and β -catenin (Figure 5E), resulting in an inhibition on Akt/mTOR and Wnt/ β -catenin pathways in RD-ES cells, while E2F6 overexpression (E2F6-OE) did no significant effect on ...
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Original Article Immunohistochemical expression of glypican 3 in endometrial carcinoma and correlation with prognostic parameters
... signaling pathways such as the WNT signaling ...the β-catenin dependent pathway has been associated with human endometrial ...signaling pathways including those triggered by ...
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Original Article Influence of regulatory intervention of Wnt/β-catenin signaling pathways on the activity of cultured and preserved articular cartilage tissues
... and β-catenin, Group C achieved higher results, and Group B obtained lower results; both groups exhibited significant differences from the control group (P < ...activated ...
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Neurokinin-1 receptor is a novel positive regulator of Wnt/ β-catenin signaling in melanogenesis
... with β-arrestin. Now the β-arrestin-biased ligands are hot studying ...with β-arrestins, which mediate NK-1R desensitization and endocytosis, terminate NK-1R signaling, and then rapid NK-1R recycling ...
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Original Article Topical application of 8DSS induces anagen hair growth in telogenic mouse skin
... signaling pathways are reported to intersect with Wnt/β-catenin signaling to regu- late ...the Wnt/β-catenin and PI3K/Akt path- ...phosphorylates β-catenin ...
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Inactivation of the Wnt/β-catenin signaling pathway underlies inhibitory role of microRNA-129-5p in epithelial–mesenchymal transition and angiogenesis of prostate cancer by targeting ZIC2
... signaling pathways, which in turn modulate cancer progression and metastasis [7, ...canonical Wnt signaling pathway, extensively conserved in the animal kingdom, is essential for embry- onic development and ...
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Wnt/β catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium
... important. Wnt/β-catenin signaling is a known oncogenic pathway that plays a well-defined role in colon and skin cancer; however, its role in lung cancer is ...of Wnt/β-catenin ...
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The anti-apoptotic PON2 protein is Wnt/β-catenin-regulated and correlates with radiotherapy resistance in OSCC patients
... in Wnt signaling to identify possible therapeutic targets by pharmacological agents or ...on Wnt signaling and its downstream effects directly, superior regulatory signal pathways are attractive ...
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HIF-1ɑ-regulated miR-1275 maintains stem cell-like phenotypes and promotes the progression of LUAD by simultaneously activating Wnt/β-catenin and Notch signaling
... signaling pathways, including the Wnt/β-catenin, Notch, and Hedgehog, have been shown to be functionally related to stemness control in multiple malignancies ...The ...
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Original Article Pegylated interferon-α inhibits the proliferation of hepatic oval cells through down-regulation of Wnt/β-catenin pathway
... of β-catenin nuclear export factor RanBP3, indicating this effect maybe in part due to suppression ofβ- catenin through upregulation of ...of Wnt/β-ca- tenin pathways, secondary ...
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Regulation of Wnt/β-catenin signaling by posttranslational modifications
... the Wnt pathway relates to protein ...core Wnt pathways proteins through lysine 63 plays an important role in the regulation of the pathway ...during Wnt-induced transcription ...of Wnt ...
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Circular RNAs Regulate Cancer Onset and Progression via Wnt/β Catenin Signaling Pathway
... signaling pathways, including the Wnt/β-catenin pathway, which controls a plethora of cellular pro- cesses that drive cancer ...and Wnt/β-catenin signaling pathway ...
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<p>Matrix Stiffness and Colorectal Cancer</p>
... signaling pathways in colorectal cancer ...of Wnt/β- catenin pathway in CRC cells, then 1) promote the translocation of β-catenin into the nucleus, and initiate a series of ...
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A Genome-Wide RNA Interference Screen Identifies a Role for Wnt/β-Catenin Signaling during Rift Valley Fever Virus Infection
... separate pathways (see Table S1 in the sup- plemental material, Panther worksheet), and the Wnt signaling pathway was the most represented pathway with 9% (8 of 89) of the genes ...the Wnt pathway ...
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PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway
... signaling pathways related to various diseases, including the Wnt/β-catenin, C/EBP, GAS, NF-κB and AP-1 pathways (Table ...the Wnt/β-catenin signaling pathway when ...
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PubMedCentral-PMC5647938.pdf
... 2009), β -catenin (Sigma; C2206; 1:500), BrdU (BD Biosciences; 347580; 1:100), cleaved-caspase3 (Cell Signaling; 9661; 1:400), Ctip2 (1:500; Abcam, ab18465), GFP (1:1000; Abcam, ab13970), Gli3 (1:500; R ...
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Original Article Activation of β-catenin causes defects in embryonic development during maternal-to-zygotic transition in mice
... that β-catenin plays basic roles in establishing epi- thelial polarity in all metazoans [19, ...Stabilized β-catenin can translocate to the nucleus, where it binds with TCF transcription ...
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LncRNA CASC11 promotes the cervical cancer progression by activating Wnt/beta-catenin signaling pathway
... Materials: Quantitative real-time polymerase chain reaction (RT-qPCR) was used to detect the expressions of CASC11 in cancerous and adjacent normal tissues of patients with cervical cancer as well as in cell lines. The ...
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