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[PDF] Top 20 A Gene Regulatory Program in Human Breast Cancer

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A Gene Regulatory Program in Human Breast Cancer

A Gene Regulatory Program in Human Breast Cancer

... Figure 2 Prediction of disease-free survival by the MR16 and cell cycle pathway changes in ER-negative breast tumors. (A and B) Kaplan – Meier curves of metastatic relapse- free survival. (A) Using the MR16 and ... See full document

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Original Article Effect of RAB25 gene on proliferation of human breast cancer cell line MCF-7 in vivo and in vitro

Original Article Effect of RAB25 gene on proliferation of human breast cancer cell line MCF-7 in vivo and in vitro

... Rab25 gene decreased the disease-free survival and the overall survival of breast cancer ...of breast cancer ...in breast cancer cell lines inhibited cell ...of ... See full document

10

Somatic mutation and functional polymorphism of a novel regulatory element in the HGF gene promoter causes its aberrant expression in human breast cancer

Somatic mutation and functional polymorphism of a novel regulatory element in the HGF gene promoter causes its aberrant expression in human breast cancer

... C/EBP-β and PARP have high binding affinity for the truncated but not wild-type DATE and are involved in HGF gene activation. The DNase I footprinting studies mentioned above identified gene ... See full document

15

State of the evidence 2017: an update on the connection between breast cancer and the environment

State of the evidence 2017: an update on the connection between breast cancer and the environment

... in gene expression in both the epithelial and stromal compart- ments of developing mammary glands from gestational day 19 ...epithelial gene expression and, ultimately, the earli- est morphological ... See full document

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Silibinin: An Inhibitor of Mir-181a Gene Expression in Sk-Br-3 Breast Cancer Cell Line

Silibinin: An Inhibitor of Mir-181a Gene Expression in Sk-Br-3 Breast Cancer Cell Line

... for breast cancer ...Mir-181a gene expression in human breast cancer cell line ...Methods: Human breast cancer cell line SK-BR-3 was treated with various ... See full document

6

VIII International Congress of the Metastasis Research Society

VIII International Congress of the Metastasis Research Society

... invasive breast cancer and the use of the anti-HER-2/neu human- ised antibody Herceptin in mouse and in ...on gene amplification rather than overex- pression of ... See full document

6

Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles

Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles

... stroma-derived gene signature that correlates with prognosis suggesting that the tumor stroma contributes significantly to the invasive and metastatic potential of tumor cells ...unique breast cancer ... See full document

13

Association of FGFR3 and FGFR4 gene polymorphisms with breast cancer in Chinese women of Heilongjiang province

Association of FGFR3 and FGFR4 gene polymorphisms with breast cancer in Chinese women of Heilongjiang province

... FGFR4 gene is located at chromosome ...as breast, colon, prostate, and sarcoma tumors ...FGFR4 gene is a missense variant. A consistent result from the Breast Cancer Association ... See full document

7

Suppression of breast cancer cell growth by Na+/H+ exchanger regulatory factor 1 (NHERF1)

Suppression of breast cancer cell growth by Na+/H+ exchanger regulatory factor 1 (NHERF1)

... [2]. Human NHERF1 is a 358-amino acid protein that shares high homologue at the modular structures with NHERF2 (also known as E3KARP or TKA1) [3]. Both contain two tandem PDZ (PSD-95/Dlg/ZO1) domains (PDZ-I and ... See full document

10

The progestational and androgenic properties of medroxyprogesterone acetate: gene regulatory overlap with dihydrotestosterone in breast cancer cells

The progestational and androgenic properties of medroxyprogesterone acetate: gene regulatory overlap with dihydrotestosterone in breast cancer cells

... global gene regulatory properties of MPA in comparison with those of progesterone in wild-type cells that express equimolar levels of PR-A and ...that regulatory levels were approximately equal, with ... See full document

15

HDAC6 activity is a non oncogene addiction hub for inflammatory breast cancers

HDAC6 activity is a non oncogene addiction hub for inflammatory breast cancers

... interrogate gene function at the genome-wide ...13 breast cancer cell lines (2 IBC and 11 non-IBC lines, including 4 luminal, 4 basal-B, 3 basal-A) and 2 non-transformed mammary epithelial lines ... See full document

14

The Role of Cytoplasmic Polyadenylation Element Binding Protein -2 (CPEB-2) in Human Breast Cancer

The Role of Cytoplasmic Polyadenylation Element Binding Protein -2 (CPEB-2) in Human Breast Cancer

... one gene, Cytoplasmic Polyadenylation Element Binding Protein-2 ...SLC-suppressing gene in breast ...HER2+ breast cancer ...tumour-suppressing gene in breast ... See full document

119

Integrative analysis of miRNA and gene expression reveals regulatory networks in tamoxifen-resistant breast cancer

Integrative analysis of miRNA and gene expression reveals regulatory networks in tamoxifen-resistant breast cancer

... (ER+) breast cancer, and has been shown to be highly effective in the adjuvant setting, with 28% reduction in mortality at 15 years of follow-up ...premenopausal breast cancer patients and for ... See full document

15

Investigating of variations in BRCA1 gene in Iranian families with breast cancer

Investigating of variations in BRCA1 gene in Iranian families with breast cancer

... female breast cancer patients who had a family history of breast cancer to find any variations in 9 exons and their near intronic regions of ...PCR program was set up for each ... See full document

5

Is MMTV associated with human breast cancer? Maybe, but probably not

Is MMTV associated with human breast cancer? Maybe, but probably not

... MMTV-related human endogenous HERV-K family of retroviruses served as an outgroup (GenBank ac- cession nos: AF020092, AF012336, AF164612, AF164614, AF164615, AF164610, M14123, AF164613, AF164609, ...Neighbor ... See full document

10

Reduction in breast cancer susceptibility due to <em>XbaI</em> gene polymorphism of alpha estrogen receptor gene in Jordanians

Reduction in breast cancer susceptibility due to <em>XbaI</em> gene polymorphism of alpha estrogen receptor gene in Jordanians

... Abstract: Breast cancer is a global health concern among women ...in breast tissues that may relate to breast cancer ...on breast cancer ...with breast ... See full document

5

Associations between single-nucleotide polymorphisms of human exonuclease 1 and the risk of hepatocellular carcinoma

Associations between single-nucleotide polymorphisms of human exonuclease 1 and the risk of hepatocellular carcinoma

... and human cells, and with MSH3 in human cells [9, ...lung cancer, colorectal cancer, gastric cancer, breast cancer, oral cancer, and other tumors [10, ...hEXO1 ... See full document

14

Tyrosine kinase signalling in breast cancer: Fibroblast growth factors and their receptors

Tyrosine kinase signalling in breast cancer: Fibroblast growth factors and their receptors

... In culture, the cellular consequences of Fgf stimulation are quite varied. For example, many are broad-spectrum mito- gens, and some induce cell motility, or alter the state of cellular differentiation (for review ... See full document

6

E2F4 regulatory program predicts patient survival prognosis in breast cancer

E2F4 regulatory program predicts patient survival prognosis in breast cancer

... work [24] to examine E2F4? s inferred functional activity through iRASs and its ability to predict survival progno- sis. In all publicly available, sufficiently sized datasets containing survival data, we have found that ... See full document

14

Recent advances in the ARID family: focusing on roles in human cancer

Recent advances in the ARID family: focusing on roles in human cancer

... ARID4B gene is also known as breast cancer-associated antigen 1 (BRCAA1) and is highly expressed in human breast, lung, colon, pancreatic, and ovarian cancers, and in normal testes, but ... See full document

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