[PDF] Top 20 Accessing Epstein-Barr Virus-Specific T-Cell Memory with Peptide-Loaded Dendritic Cells
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Accessing Epstein-Barr Virus-Specific T-Cell Memory with Peptide-Loaded Dendritic Cells
... the peptide-DC stimula- tion protocol is in the selective reactivation of responses to subdominant latent cycle proteins, in particular proteins which constitute potentially useful targets for the immune therapy ... See full document
9
Regression of Epstein-Barr Virus-Induced B-Cell Transformation In Vitro Involves Virus-Specific CD8+ T Cells as the Principal Effectors and a Novel CD4+ T-Cell Reactivity
... antigen- specific T-cell memory ...a memory T-cell response; EBV nonimmune (seronegative) donor cultures show continued B-cell growth irrespective of the presence ... See full document
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Holoendemic Malaria Exposure Is Associated with Altered Epstein-Barr Virus-Specific CD8+ T-Cell Differentiation
... ⫹ T cells in children residing in a region with holoendemic malaria ...⫹ T-cell immunity in areas with divergent malaria endemicity might pro- vide a better window into the complex etiology of ... See full document
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Cross reactive influenza virus–specific CD8+ T cells contribute to lymphoproliferation in Epstein Barr virus–associated infectious mononucleosis
... cross-reactive cells are maintained in memory and their functional responses to either antigen can include cytotoxicity and the produc- tion of MIP-1b, IFN-γ, and ...Cross-reactive T cells may ... See full document
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Memory CD8+ T Cells Specific for a Single Immunodominant or Subdominant Determinant Induced by Peptide-Dendritic Cell Immunization Protect from an Acute Lethal Viral Disease
... that specific CD8 ⫹ T cell response, which can be detected only when the ID determinant is absent during priming (39, 40, ...⫹ T cell determinants recognized in Sendai virus can ... See full document
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T Cell Epitope Clustering in the Highly Immunogenic BZLF1 Antigen of Epstein-Barr Virus
... response, T cells from donor MR67 were tested for recognition of various concentrations of the 189 CRAKFKQLL 197 epitope versus the 189 CRAKFKHLL 197 vari- ant (the variant residue is ...on T ... See full document
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Acquisition of Polyfunctionality by Epstein-Barr Virus-Specific CD8+ T Cells Correlates with Increased Resistance to Galectin-1-Mediated Suppression
... function, cells producing either TNF alone or TNF and IFN- ␥ cells were ...LMP-1/2. Cells were harvested seven days later, stained with anti-CD8, and assessed for cell division on a ... See full document
7
Tonsillar homing of Epstein Barr virus–specific CD8+ T cells and the virus host balance
... these memory populations in the blood; in contrast, circulating CMV-specific memory cells are almost entirely devoid of these markers (45, ...that T cells receive spe- cific ... See full document
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Epstein-Barr virus–specific T cell therapy for progressive multiple sclerosis
... remyelination, dendritic and axonal sprouting, and synaptic ...first T cell infusion. Killing of EBV-infected B cells in lymphoid tissue, including the cervical lymph nodes, where EBV-infected ... See full document
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The human T cell immune response to Epstein Barr virus
... CD8 T cell responses, our data showed that they are highly focused against early lytic ...EBV-specific T cells within inflammed lesions of patients suffering from autoimmune diseases is ... See full document
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Isolation of intertypic recombinants of Epstein-Barr virus from T-cell-immunocompromised individuals.
... of Epstein-Barr virus (EBV) analyzed to date for allelic polymorphisms of the nuclear antigen EBNA2 gene (in the BamHI YH region of the genome) and of the EBNA3A, -3B, -3C genes (tandemly arranged in ... See full document
9
Persistence of Epstein-Barr Virus in Self-Reactive Memory B Cells
... infected memory B cells have not been identified in vivo, and the model does not account for the origin of EBV-infected ...B cells of particular developmental stages (4) and anatomic loca- tions in ... See full document
11
MicroRNAs of Epstein Barr Virus Attenuate T Cell Mediated Immune Control In Vivo
... the virus to persist, while most of the immune evasive proteins encoded by the virus are expressed only during lytic repli- ...blocks peptide import into the endoplasmic reticulum (ER) via the ... See full document
15
Immunophenotyping of Nodal Peripheral T-cell Lymphomas and its Association with Epstein-Barr Virus
... null cell variant of ...null cell ALCL-ALK positive ...of T-cell markers could predict an advanced stage (stage IV disease), an attempt was made at statistical ...individual ... See full document
8
Specific cytotoxic T lymphocytes recognize the immediate-early transactivator Zta of Epstein-Barr virus.
... EBV-infected cells by means of Zta-specific CTL are op- erative in large parts of the ...Zta- specific CTL restricted by other HLA molecules which have not yet been discovered because of the ... See full document
8
β1 Integrin Expression Increases Susceptibility of Memory B Cells to Epstein-Barr Virus Infection
... tonsillar memory B cells with EBV which, in addition to primary infec- tion of naïve (33) and GC B cells (2, 19), contributes to a more efficient establishment of EBV ...the memory B ... See full document
11
Enhanced Expression of Cell Cycle Regulatory Genes in Virus-Specific Memory CD8+ T Cells
... effector cells contracts until it ultimately constitutes approximately ⬃5 to 10% of the total T-cell ...“memory” cells remaining after the con- traction phase progressively developed ... See full document
7
Posttranslational processing of an Epstein-Barr virus-encoded membrane protein expressed in cells transformed by Epstein-Barr virus.
... However, for the following reasons we presume they represent proteolytic degradation products generated in vivo: i immunoprecipitates of COS cells electroporated with pSV2CAT a plasmid s[r] ... See full document
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Epstein-Barr Virus-Lymphoid Cell Interactions III. Effect of Concanavalin A and Saccharides on Epstein-Barr Virus Penetration
... Our data indicate that: i EBV penetration into target cells is blocked by ConA and high sucrose concentration 0.25 M at a trypsinsensitive stage on the cell surface; ii lower concentrati[r] ... See full document
9
Dendritic cells loaded with killed breast cancer cells induce differentiation of tumor specific cytotoxic T lymphocytes
... Given the limited availability of defined breast tumor-asso- ciated antigens, the present study was designed to identify conditions permitting the loading of DCs with killed allo- genic breast cancer cell lines. ... See full document
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