[PDF] Top 20 Activity, expression and function of a second Drosophila protein kinase A catalytic subunit gene.
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Activity, expression and function of a second Drosophila protein kinase A catalytic subunit gene.
... structure, and expression of the gene for a novel regulatory subunit of cAMPdependent protein kinase in Genorhabditis elegans. FIRTEL, 1991 A developmentally regulate[r] ... See full document
14
Attenuation of DNA-dependent protein kinase activity and its catalytic subunit by the herpes simplex virus type 1 transactivator ICP0.
... DNA-PK activity is an im- portant mechanism for increasing the levels of RNAP II tran- scription on viral DNA or on transfected ...DNA-PKcs subunit of DNA-PK, may facilitate enhanced levels of RNAP II ... See full document
7
Catalytic Subunit 1 of Protein Phosphatase 2A Is a Subunit of the STRIPAK Complex and Governs Fungal Sexual Development
... and kinase (STRIPAK) complex, which has been described in organisms ranging from yeasts to ...heterotrimeric protein phosphatase PP2A is a subunit of STRIPAK. Here, catalytic subunit 1 ... See full document
11
Toxoplasma gondii Cyclic AMP Dependent Protein Kinase Subunit 3 Is Involved in the Switch from Tachyzoite to Bradyzoite Development
... high expression of TgPKAc2 during the sexual developmental life cycle of ...PKA catalytic subunits in phylogenetic analysis and localization ...-3 expression constructs driven by the GRA1 promoter, ... See full document
12
The regulation and function of phosphatidylinositol 3-kinase
... The second group of class I Pi 3-kinases, class lA, includes the first member of the PI 3-kinase family to be ...PI kinase activity which associated tightly with the transforming ... See full document
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Isolation of Mutations in the Catalytic Domain of the Snf1 Kinase That Render Its Activity Independent of the Snf4 Subunit
... enzyme activity in ...Snf1 kinase invoke a similar regulatory role for a region im- mediately C terminal of the Snf1 kinase domain (12, ...yeast, Drosophila, and various mammalian species ... See full document
9
Myocardial insufficiency is related to reduced subunit 4 content of cytochrome c oxidase
... tractile function [26] and appears as a sufficient model to understand pathogenesis of myocardial insufficiency and cardiac failure, ...thymidine kinase activity in as- sociation with mtDNA depletion ... See full document
9
Genetic Evidence for a Protein Kinase A/Cubitus Interruptus Complex That Facilitates Processing of Cubitus Interruptus in Drosophila
... by protein kinase A (PKA), inducing proteolysis to Ci-75, a transcriptional ...target gene expression caused by mutant forms of PKA regulatory (PKAr) and catalytic (PKAc) subunits and ... See full document
10
IDENTIFICATION OF HUMAN cAMP DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT INHIBITORS
... holoenzyme activity is directly related to the progression of cancers 5 ...over expression of cAMP dependent protein kinase catalytic subunit (PKACA) causes severe tumorgenesis ... See full document
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A Novel Phosphoregulatory Switch Controls the Activity and Function of the Major Catalytic Subunit of Protein Kinase A in Aspergillus fumigatus
... PkaC1 function and ...PKA catalytic subunit TPK1, which has the highest homology to ...the catalytic core region, we ex- pected this approach to provide a close approximation of the true ... See full document
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THE EFFECT OF THEOPHYLLINE ON THE KINETICS OF cAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT, cAMP, PROTEIN KINASE INHIBITOR AND THEIR RELATIONSHIP IN LUNG TISSUE
... the activity of cAMP-dependent protein kinase at the ceUular level contribute to the underst'Ulding of the mechanisms for these ...a function of theophylline concen ...C subunit in the ... See full document
6
The AMP activated protein kinase α2 catalytic subunit controls whole body insulin sensitivity
... AMPKα2 gene knockout ...(Strata- gene, Loyola, California, ...AMPKα2 catalytic domain (corresponding to amino acids 189–260), with loxP sites for the Cre recombinase and inserting a PGK ... See full document
9
Recent advances in animal and human pluripotent stem cell modeling of cardiac laminopathy
... such protein in car- diac disease ...determine gene dose effects of the heterogeneous and homogeneous mutation system, the animal replicated clinical phenotypes with muscle dystrophy, premature DCM ... See full document
9
Genetic Interactions Between REG1/HEX2 and GLC7, the Gene Encoding the Protein Phosphatase Type 1 Catalytic Subunit in Saccharomyces cerevisiae
... Mutations in GLC7, the gene encoding the type 1 protein phosphatase catalytic subunit, cause a variety of abberrant phenotypes in yeast, such as impaired glycogen synthes[r] ... See full document
9
FUNCTIONAL GENOMICS OF MYCOBACTERIUM TUBERCULOSIS
... INTRODUCTION: The proteomics of Mycobacterium tuberculosis was intensively studied to expand our knowledge base and identify proteins or enzymes that would serve as targets for few antibiotics, many number of proteins ... See full document
6
Suppression of v-src Transformation by the drs Gene
... 4. Expression of endogenous and exogenous drs mRNA in F2408 and F-drs cells (A and C) and the effect of MRSV infection on drs mRNA expression ...The expression vector in this experiment was pSRaNeo, ... See full document
6
Increased expression of the PI3K catalytic subunit p110δ underlies elevated S6 phosphorylation and protein synthesis in an individual with autism from a multiplex family
... Functional screens in peripheral blood cell lines are suitable to detect signaling defects in idiopathic autism We used lymphoblastoid cell lines from patients with autism of unknown etiology obtained from the AGRE ... See full document
12
Cell Signalling in Limb Development and Hindbrain Segmentation
... the function of Cek-8, f^A-receptor activation requires binding by membrane-associated ligands (Davis et al ...its expression domain and, second, CEK-8 may be activated throughout its ...mutual ... See full document
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The 86 kD subunit of Ku autoantigen mediates homotypic and heterotypic adhesion of multiple myeloma cells
... nuclear protein named Ku (19). This protein is composed of 70- and 86-kD subunits (31, 32), each of which has phospho- serine residues (33) and DNA binding regions ...the catalytic subunit of ... See full document
11
The secret life of kinases: functions beyond catalysis
... the expression of iNOS, COX-2, MYBL2 (B-Myb), and AURKA (Aurora A) genes ...target gene expression could be inhibited by EGFR inhibitor drugs, gene transactivation seems to require ... See full document
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