[PDF] Top 20 Meta analysis on the association between pathologic complete response and triple negative breast cancer after neoadjuvant chemotherapy
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Meta analysis on the association between pathologic complete response and triple negative breast cancer after neoadjuvant chemotherapy
... subgroup analysis outcomes are shown in Table ...of chemotherapy inter- mission was not used due to a lack of similar data in these ...of chemotherapy regi- men (anthracycline-based, ... See full document
12
The effect of neoadjuvant platinum-based chemotherapy in BRCA mutated triple negative breast cancers -systematic review and meta-analysis
... Background: Triple negative breast cancers (TNBC) are associated with an aggressive clinical course, earlier recurrence and short ...of response to platinum ...the pathologic ... See full document
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Better pathologic complete response and relapse-free survival after carboplatin plus paclitaxel compared with epirubicin plus paclitaxel as neoadjuvant chemotherapy for locally advanced triple-negative breast cancer: a randomized phase 2 trial
... pathologic complete response (pCR) rate (28%) than those of anthracycline-based (20%) or taxane-based (12%) regimens ...in neoadjuvant setting. A pCR rate of 38.9% was observed after ... See full document
10
Diffusion weighted imaging in monitoring the pathological response to neoadjuvant chemotherapy in patients with breast cancer: a meta analysis
... A 2-by-2 contingency table separating patients into TP, TN, FP, and FN groups was constructed for each enrolled study. Based on this table, sensitivity and specificity were calcu- lated. Diagnostic odds ratio (DOR) was ... See full document
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<p>Prediction of Pathologic Complete Response by Ultrasonography and Magnetic Resonance Imaging After Neoadjuvant Chemotherapy in Patients with Breast Cancer</p>
... a complete response on both US or MRI and pathology, false positive (FP) as a complete response on US or MRI (Figure 1), but presentation of a residual tumor on pathology, true nega- tive (TN) ... See full document
10
Survival is associated with complete response on MRI after neoadjuvant chemotherapy in ER positive HER2 negative breast cancer
... Although the total study group is relatively large, only 35 recurrences occurred during a follow-up time that is relatively brief for ER-positive/HER2-negative (luminal) tumors. This resulted in wide confidence ... See full document
12
AKT1low quiescent cancer cells persist after neoadjuvant chemotherapy in triple negative breast cancer
... adjuvant chemotherapy are incompletely ...primary chemotherapy resistance in patients with ...drug-resistant, cancer cell state in residual TNBC after NACT has remained ...quiescent ... See full document
12
Triple negative breast cancer in Moroccan women: clinicopathological and therapeutic study at the National Institute of Oncology
... Breast cancer affected an estimated 232,620 women and men in 2011, and was responsible for 39,970 deaths dur- ing the same year, in the United States ...[4]. Triple-negative breast ... See full document
9
Ki 67 can be used for further classification of triple negative breast cancer into two subtypes with different response and prognosis
... in breast cancer patients receiving neoadjuvant chemotherapy ...higher response rate to neoadjuvant chemotherapy in breast cancer [9,11,34,35,37], although ... See full document
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A case of HER 2 positive recurrent breast cancer showing a clinically complete response to trastuzumab containing chemotherapy after primary treatment of triple negative breast cancer
... computed tomography (CT) scan confirmed left axillary and infraclavicular lymph node swellings. FDG-PET (2- [18F]Fluoro-2-deoxyglucose positron emission tomogra- phy) showed an accumulation of FDG in the left axilla and ... See full document
5
A combination of Nottingham prognostic index and IHC4 score predicts pathological complete response of neoadjuvant chemotherapy in estrogen receptor positive breast cancer
... (ER+) breast cancer accounts for approximately 60% of all primary breast cancer cases ...recurrences after treatment, and younger patients (age≤ 40 years) are found to have a much ... See full document
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Lymphocyte density determined by computational pathology validated as a predictor of response to neoadjuvant chemotherapy in breast cancer : secondary analysis of the ARTemis trial
... in breast cancer ...systematic analysis of quantitative pathology metrics in the Neo-tAnGo trial [2] and found that pre-treatment tumour lymphocyte density was inde- pendently associated with ... See full document
5
Serum biomarker profiles and response to neoadjuvant chemotherapy for locally advanced breast cancer
... Multiplex analysis of serum levels of various biomarkers in LABC patients receiving neoadjuvant chemotherapy Of the 44 evaluable patients enrolled in the clinical trial, 12 demonstrated a cCR, 20 ... See full document
9
Neural Network Ensemble for the Prediction Of Pathological Complete Response After Neoadjuvant Chemotherapy for Breast Cancer
... breast cancer in accordance to their dataset ...in cancer prediction/ ...that after Neoadjuvant Chemotherapy, patients who attain pathological complete response ... See full document
6
Assessment of Pathological Response to Neoadjuvant Chemotherapy in Locally Advanced Breast Carcnoma
... randomized after modified radical mastectomy to receive radiation therapy alone; vincristine, doxorubicin (Adriamycin), and cyclophosphamide (VAC) chemotherapy alone; or radiotherapy and VAC ...and ... See full document
82
A two-gene epigenetic signature for the prediction of response to neoadjuvant chemotherapy in triple-negative breast cancer patients
... of triple- negative breast cancer (TNBC) patients treated with neo- adjuvant systemic chemotherapy (NAC) depending on the treatment response and identified a two-gene epigenetic ... See full document
11
Tumor-infiltrating Lymphocytes are Independent Favorable Prognostic Indicator in 17-year Disease- Free Survival in Lymph Node-Negative Triple- Negative Breast Cancer Patient
... two meta-analyses, pooled analysis showed that dense TIL indicates high pathologic response rates to neoadjuvant chemotherapy and may lead to favorable ...of pathologic ... See full document
15
Effect of neoadjuvant chemotherapy regimen on relapse free survival among patients with breast cancer achieving a pathologic complete response: an early step in the de escalation of neoadjuvant chemotherapy
... adjuvant chemotherapy, and they merit future ...treatment response after only a few cycles of chemotherapy, we may be able to adminis- ter taxane and HER2-targeted therapies only, and avoid ... See full document
10
Selective elimination of breast cancer surgery in exceptional responders: historical perspective and current trials
... in chemotherapy regimens, targeted therapies, and our fundamental understanding of the relationship of tumor subtype and pathologic complete response (pCR), there has been dramatic improvement ... See full document
8
TUMOUR INFILTRATING LYMPHOCYTES AS A PROGNOSTIC AND PREDICTIVE FACTOR FOR NEOADJUVANT CHEMOTHERAPY IN TRIPLE NEGATIVE BREAST CANCER
... Background: Triple negative breast cancer is a subtype of breast cancer that shows minimal or no immunohistochemical expression of estrogens receptor, progesterone receptor and ... See full document
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