[PDF] Top 20 Analysis of the Cytosolic Domains of the Hepatitis B Virus Envelope Proteins for Their Function in Viral Particle Assembly and Infectivity
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Analysis of the Cytosolic Domains of the Hepatitis B Virus Envelope Proteins for Their Function in Viral Particle Assembly and Infectivity
... the envelope proteins while preserving that of the viral ...ayw3 viral genome) between positions 701 and 1349 in the pCI vector (Pro- mega) to allow the initiation of pregenomic HBV RNA ... See full document
11
Role of N Glycosylation of Hepatitis B Virus Envelope Proteins in Morphogenesis and Infectivity of Hepatitis Delta Virus
... velope proteins are not required for HDV entry in vitro, and only the presence of unglycosylated S and L proteins at the virion surface is sufficient for ...Duck hepatitis B virus, the ... See full document
5
The Pre-S1 and Antigenic Loop Infectivity Determinants of the Hepatitis B Virus Envelope Proteins Are Functionally Independent
... the virus. The HBV envelope proteins bear at least two deter- minants of viral entry: (i) the 75 first residues of pre-S1 (4, 30) and (ii) the conformational AGL determinant (2, ...duck ... See full document
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Hepatitis B Virus Surface Antigen Assembly Function Persists when Entire Transmembrane Domains 1 and 3 Are Replaced by a Heterologous Transmembrane Sequence
... on particle formation to enhance vaccine ...vated viral particles, such as inactivated polio vaccine (48) and rabies (35), and recombinant proteins that form virus-like par- ticles, such as ... See full document
10
A Tryptophan-Rich Motif in the Carboxyl Terminus of the Small Envelope Protein of Hepatitis B Virus Is Central to the Assembly of Hepatitis Delta Virus Particles
... The hepatitis delta virus (HDV) particle consists of an outer envelope provided by the helper hepatitis B virus (HBV) and an inner ribonucleoprotein ...encoded ... See full document
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Mutations in the Carboxyl-Terminal Domain of the Small Hepatitis B Virus Envelope Protein Impair the Assembly of Hepatitis Delta Virus Particles
... The assembly of hepatitis delta virus (HDV) particles de- pends upon the presence of hepatitis B virus (HBV) for the supply of its envelope proteins ...HDV ... See full document
8
Mutagenesis of the DI/DIII Linker in Dengue Virus Envelope Protein Impairs Viral Particle Assembly
... Immunofluorescence analysis of E and C proteins following electroporation of cells with genomic RNAs encoding wild-type virus and DI/DIII linker mutants indicated that these two struc- tural ... See full document
12
Role of the Pre-S2 Domain of the Large Envelope Protein in Hepatitis B Virus Assembly and Infectivity
... normal cytosolic position of the pre-S domain, could be explained by a conformational modification of the cytosolic sequence, which might reduce the accessibility of the interac- tion ...the envelope ... See full document
6
Charged Residues in the Transmembrane Domains of Hepatitis C Virus Glycoproteins Play a Major Role in the Processing, Subcellular Localization, and Assembly of These Envelope Proteins
... the particle. Viral envelope proteins can play a major role in virus budding (26), which is a late stage of virus assem- bly corresponding to the acquisition of a membrane that ... See full document
11
Role for Calnexin and N-Linked Glycosylation in the Assembly and Secretion of Hepatitis B Virus Middle Envelope Protein Particles
... secreted viral and subviral particles (9, ...membrane proteins, the supernatant fraction should harbor soluble cytosolic and soluble intraluminal pro- teins leaked from intracellular cisternae during ... See full document
5
Two Potentially Important Elements of the Hepatitis B Virus Large Envelope Protein Are Dispensable for the Infectivity of Hepatitis Delta Virus
... three envelope proteins, large (L), middle (M), and small (S), that have a common C ...two envelope pro- teins, L and S ...L proteins of representative HBV and DHBV, with results as summarized ... See full document
5
The First Transmembrane Domain of the Hepatitis B Virus Large Envelope Protein Is Crucial for Infectivity
... analysis demonstrated that deletions in the N-terminal part of the L protein S domain did not affect par- ticle assembly except for one mutation, LM ⌬ (I188/I191), which prevented complete viral ... See full document
11
The Pre-S2 Domain of the Hepatitis B Virus Is Dispensable for Infectivity but Serves a Spacer Function for L-Protein-Connected Virus Assembly
... for virus entry have been demonstrated in well-defined in vitro infection systems, the respective role of the viral M protein and the pre-S2 domain as a constitutive subdomain of the L protein gave rise to ... See full document
10
Hepatitis B Virus Subviral Envelope Particle Morphogenesis and Intracellular Trafficking
... surface proteins are not only incorporated into virion en- velopes but they also bud to generate empty subviral spherical or filamentous particles without nucleocapsids in an intracel- lular compartment, with ... See full document
10
NS3 Helicase Domains Involved in Infectious Intracellular Hepatitis C Virus Particle Assembly
... of virus in RNA-transfected cells. The abundance of HCV RNA and viral proteins could be affected not only by RNA replication but also by spread of virus within a ...mutation. Viral RNA ... See full document
16
Support of the Infectivity of Hepatitis Delta Virus Particles by the Envelope Proteins of Different Genotypes of Hepatitis B Virus
... quantitative analysis of the different concentrated HDV virus stocks are summarized in Table ...of envelope proteins in the ...S envelope protein, while only a fraction of virions bore ... See full document
13
Structure-Function Analysis of Hepatitis C Virus Envelope-CD81 Binding
... digestion analysis of covalent binding between fragments G and H, together with the unlikely possi- bility of disulfide binding between two adjacent cysteines, allow us to exclude the partnering between Cys175 and ... See full document
7
The spacer peptide between human immunodeficiency virus capsid and nucleocapsid proteins is essential for ordered assembly and viral infectivity.
... in viral replication as has been shown for poliovirus interme- diate processing products ...or function of the mature virion. Sequence analysis of proteins from mature HIV-1 particles as well ... See full document
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Capsid assembly and involved function analysis of twelve core protein mutants of duck hepatitis B virus.
... Much attention was focused on the C-terminal region of this protein, in which several domains have been found to mediate different functions in the viral life cycle; e.g., the C-terminal[r] ... See full document
8
Hepatitis C virus envelope proteins bind lactoferrin.
... GST-fused proteins derived from constructs 1 to 8 are 26, 43, 32, 38, 58, 40, 37, and 34 kDa, ...GST-fused proteins were expressed in ...GST-fused proteins were incubated with protein A ... See full document
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