[PDF] Top 20 Association of TLR8 and TLR9 polymorphisms with tuberculosis in a Chinese Han population: a case control study

... Our study faced some intrinsic ...TB case of the first sample included both clinical diagnosed and bacteria confirmed TB patients, regardless of their types, which could potentially reduce the validity of ... See full document

... Some polymorphisms in NOS1 gene can directly affect the expression of mRNA, which change the levels of NO [46, ...Future association studies with more sys- temic SNPs selection are thought to be needed to ... See full document

... our study a lower frequency of the G allele and the GG genotype in rs1799971 and rs2075572 was found in patients with ...in association studies may be attributed to genetic het- erogeneity since the various ... See full document

... and control subjects This hospital-based case – control study involved 232 CD patients and 272 healthy controls of Chinese Han popu- lation recruited from the Department of ... See full document

... the control group was analyzed for Hardy-Weinberg equilibrium (HWE) using chi-square test and exact test, SNPs were excluded from the analysis if they were out of HWE ... See full document

... In addition to its crucial role in controlling adipogene- sis and fat distribution, emerging evidence from meta- bolic studies [20–22] has shown that NCOA3 can participated in metabolic control and energy ... See full document

... methods Study population All subjects were members of Chinese Tibetan population living in the Tibet Autonomous Region of ...pulmonary tuberculosis and were characterized ... See full document

... our study should be considered. First, the sample size of our study was relatively ...this study were limited to the Han Chinese population; there- fore, it is unknown whether ... See full document

... this case-control study, including 1813 MetS cases and 2037 healthy ...the association between two novel single nucleotide polymorphism (SNPs) of BUD13 (rs7118999 and rs10488698) and MetS and ... See full document

... Although the role of Kv2.1 channel in lipid and fat metabolism has not been assessed, previous reports could provide some clues. Besides the simple diffusion manner, fatty acids, previously thought to be transported ... See full document

... This study, to our knowledge, is the first to pres- ent IL1R1 polymorphisms and AS suscepti- bility in a Northwest Chinese Han ...cluster polymorphisms and AS risk in Taiwanese ... See full document

... the association of interactions between vascular endothelial growth fac- tor (VEGF) gene rs3025039 and rs3025021 polymorphisms and environmental factors with ischemic stroke (IS) and its subtypes in ... See full document

... this study, the frequency of the A allele of rs1876487 in the schizophrenic patients was lower compared to the controls in the female subgroup ...a study by Sumi and Ignarro verified that estrogen-related ... See full document

... (SHINING) study was conducted by Beijing Hyperten- sion League Institute from 1997 to ...SHINING study comprised of subjects exclusive to Han ...(CT)/MRI. Control subjects were selected ... See full document

... This study tried to examine the single-nucleotide polymorphisms (SNPs) of ADAM12 for their association with knee OA susceptibility in a Chinese Han ...a Chinese Han ... See full document

... IL-16 polymorphisms with ovarian can- cer risk, there were several limitations that need to be addressed regarding the present ...ease association and gene-environment inter- ...larger study groups ... See full document

... previous study, the increased go- nadotropin concentrations, morphological changes of the ovary and the depletion of primordial follicles began to appear 12 weeks postnatal in PTEN mutant ...The association ... See full document

... our study, all of these SNPs were in Hardy- Weinberg equilibrium in our samples, but we failed to observe any statistical significance neither in allele and genotypes frequencies of the SNPs nor in the frequency ... See full document

... the association of SNPs in miR-143 with human cancers and found that SNPs (such as rs4705343 and rs353292) in miR-143 are associated with several ...current study, we found that allele T of rs4705343 was ... See full document

... Genome-wide association study (GWAS) has revealed that the SLC22A3-LPAL2-LPA gene cluster was a risk locus for coronary artery disease, and the chromosomal region (6p26) where the SLC22A3-LPAL2-LPA gene ... See full document