[PDF] Top 20 Barrier function regulates epidermal DNA synthesis
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Barrier function regulates epidermal DNA synthesis
... permeability barrier regulates epidermal DNA synthesis in two acute and two chronic models of barrier ...acetone, DNA synthesis is increased 102%, in tape-stripped ... See full document
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Ceramides metabolism and impaired epidermal barrier in cutaneous diseases and skin aging: focus on the role of the enzyme PNPLA1 in the synthesis of ω-O-acylceramides and its pathophysiological involvement in some forms of congenital ichthyoses☆
... main function of the epidermis, the barrier function, vital for the ...permeability barrier function by dampening trans- epidermal loss of water and electrolytes and by ... See full document
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Hypercholesterolemia in young adult APOE−/− mice alters epidermal lipid composition and impairs barrier function
... associated barrier function in young adult low-density lipoprotein receptor knockout (LDLR −/− ) and apolipoprotein E knockout (APOE −/− ) mice, two commonly used hypercholesterolemic mouse models ... See full document
9
The effect of Psoroptes ovis infestation on ovine epidermal barrier function
... As reported earlier, transcriptome microarray analysis of the ovine cutaneous response to P. ovis demonstrated that expression of a cluster of EDC genes including those for FLG, LOR and IVL was decreased with max- imal ... See full document
11
Water relations of tetrapod integument
... the epidermal water barrier of amniotes are lamellar bodies, which are discreet lipid-enriched secretory organelles first observed by Selby (1957) and later described in detail by Odland (1960) and Elias ... See full document
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Fatty acids are required for epidermal permeability barrier function
... permeability barrier is mediated by a mixture of ceramides, sterols, and free fatty acids arranged as extracellular lamellar bilayers in the stratum ...normal barrier function, definitive evidence ... See full document
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Sphingolipids are required for mammalian epidermal barrier function Inhibition of sphingolipid synthesis delays barrier recovery after acute perturbation
... the epidermal permeability ...in epidermal barrier function lead to a rapid increase in cholesterol and fatty acid synthesis which parallels the early stages of the repair ...the ... See full document
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Up regulation of tight junction related proteins and increase of human epidermal keratinocytes barrier function by Saccharomycosis ferment filtrate
... cutaneous barrier recovery after tape stripping in a study using hairless mouse ...rier function of ...better barrier function of epidermal keratinocytes is wor- thy of further ... See full document
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Mutations in the human SC4MOL gene encoding a methyl sterol oxidase cause psoriasiform dermatitis, microcephaly, and developmental delay
... isoprenoid synthesis (34) or abnormal cholesterol composition of lipid rafts in immu- nocytes ...Since epidermal lipid composition is important for skin barrier function, a defect in de novo ... See full document
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Cholesterol synthesis is required for cutaneous barrier function in mice
... lipid synthesis which is associated with the rapid restoration of stratum corneum lipids and barrier ...cholesterol synthesis in the barrier ...cholesterol synthesis. After acetone ... See full document
9
Role of Integrin-linked kinase in epidermal integrity and barrier function
... junctions function as gates in the epidermis, to modulate diffusion of small soluble ...of epidermal barrier function (24, ...ZO-1 regulates epithelial proliferation, and it inversely ... See full document
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Dendritic epidermal T cells regulate skin antimicrobial barrier function
... induces epidermal host-defense molecules upon skin barrier dis- ruption to aid the wound-healing ...IL-17A regulates distinct AMP production in epithelial cells and tis- sues (50, 55), this prompted ... See full document
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Nontranslational function of leucyl tRNA synthetase regulates myogenic differentiation and skeletal muscle regeneration
... negatively regulates myogenesis in ...LRS function in myogen- esis, we considered the role of LRS as a leu- cine sensor that activates the Rag GTPases upstream of mTORC1 in cell growth regulation (7, ... See full document
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DNA Supercoiling Regulates the Motility of Campylobacter jejuni and Is Altered by Growth in the Presence of Chicken Mucus
... identified DNA supercoiling as playing a key role in regulating motility and flagellar protein production and found that this supercoiling-controlled regulon is induced by growth in chicken ...resting DNA ... See full document
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Involved and uninvolved skin from psoriatic subjects: are they equally diseased? Assessment by skin transplanted to congenitally athymic (nude) mice
... in epidermal proliferation of skin of subjects with psoriasis and that disease expression is governed by other host ...compared epidermal proliferation of skin involved and uninvolved with psoriasis with ... See full document
11
Neurotrophic factor GDNF regulates intestinal barrier function in inflammatory bowel disease
... The barrier destabilizing effect of p38 MAPK activated in response to TNF-α in intestinal epithelium is also supported by our previous study in which inflammatory stimuli induced strong activation of p38 MAPK ... See full document
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A nervous breakdown in the skin: stress and the epidermal barrier
... In this issue of the JCI, Aberg and colleagues report that psychological stress disrupts the skin’s antimicrobial barrier and increases the severity of cutane- ous infections (see the related article beginning on ... See full document
5
Current Perspectives Series: Filaggrin in Atopic Dermatitis
... Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis.. Weidinger S, Illig T, Baurecht H, Irvine AD, Rodriguez[r] ... See full document
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REVIEW ARTICLE Molecular Genetics of Childhood Cancer: Implications for Pathogenesis, Diagnosis, and Treatment
... Identification of consistent chromosomal translo- cations associated with specific tumor types has aided the diagnosis of pediatric soft tissue sarcomas (Table 3), although interpretable karyotypes are ob- tained in less ... See full document
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DNA infectivity and the induction of host DNA synthesis with temperature-sensitive mutants of simian virus 40.
... This, and the fact that mutants of the A group induce host DNA synthesis in CV-1 cells although they do not replicate viral DNA at 40 C 5, 18 suggested either that an early function othe[r] ... See full document
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