Top PDF A Case of Basal Cell Adenoma of the Upper Lip

A Case of Basal Cell Adenoma of the Upper Lip

A Case of Basal Cell Adenoma of the Upper Lip

BCA has sometimes been mistaken for ACC. Jung et al. [8] reported that, compared to BCA without capsular invasion, the BCACs and BCAs with capsular invasion were more likely to be larger and have solid or cribriform patterns and most BCACs and BCAs exhibited nuclear beta-catenin expression, and beta-catenin, CK5/6, CD117, and S-100 protein were helpful for differentiating basal cell neoplasms from ACC. BCAs with capsular invasion shared several pathological features with BCACs, including a large size and frequent cribriform patterns but the malignant potential of these tumors seems highly limited and should be reexamined. Jung et al. [8] also reported that beta-catenin immunostaining may aid the differential diagnosis between basal cell neoplasms and ACCs.
Show more

5 Read more

Nasal and Upper Lip Reconstruction of a Case of Squamous Cell Carcinoma Nose  Stage IV—A Case Report

Nasal and Upper Lip Reconstruction of a Case of Squamous Cell Carcinoma Nose Stage IV—A Case Report

We report a case of 77 years old male patient who presented to our hospital with bleeding from a fungating mass of the nose. Investigations revealed the lesion to be moderately differentiated ba- saloid type squamous cell carcinoma, with lung, liver and spleen metastasis. Oncologists started palliative chemotherapy for the patient. Excision of the tumour required removal of most of the nose including the lateral nasal cartilages and the nasal septum. Nasal reconstruction was done by using left nasolabial flap after deepithelialising 3 parts of it and covering that flap with a forehead flap. Residual tumour of the upper lip required further excision later on and coverage with a fan flap. The patient survived about 6 months after the surgery in a good appearance and was ac- cepted and approached well by his family. We think that this type of reconstruction is suitable for late stages cancer nose considering the life expectancy of this category of patients.
Show more

9 Read more

Local recurrence of sclerosing mucoepidermoid carcinoma with eosinophilia in the upper lip: a case report

Local recurrence of sclerosing mucoepidermoid carcinoma with eosinophilia in the upper lip: a case report

Case presentation: A 61-year-old Japanese man was referred to our hospital with a mass in his median upper lip of four years ’ duration. An examination of his median upper lip revealed a well-defined tumor measuring 9×12mm in diameter, which was subsequently resected. Three years after the first surgery, the tumor recurred and was resected. Both tumors were confirmed by histopathology to be sclerosing mucoepidermoid carcinoma with eosinophilia. Neither recurrence nor metastasis was observed in three and a half years of follow-up after the second surgery.

5 Read more

Original Article Basal cell adenoma of the parotid gland: clinical and pathological findings in 29 cases

Original Article Basal cell adenoma of the parotid gland: clinical and pathological findings in 29 cases

Abstract: Objective: To determine the clinical and pathological features of basal cell adenoma (BCA) of the parotid gland. Methods: This is a retrospective study of 29 parotid BCAs in 28 patients who underwent surgery at the Department of Otolaryngology Head and Neck Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, between October 2000 and June 2013. The tumors were categorized according to their location in the parotid gland as superior superficial lobe, inferior superficial lobe and deep lobe. Results: The mean age was 57.0 years (range, 32-83 years). The clinical manifestations of parotid BCAs were consistent with those of other benign parotid tumors. There were no significant differences in age, average disease duration and tumor size among the three tumor groups. There were 11 deep tumors (11/29, 37.9%), and five of them exhibited cystic degeneration (5/11, 45.5%). A total of 15 patients underwent FNAB examination, and the results were positive in seven patients (7/15, 46.7%). Mild facial nerve function impairment occurred in five patients (House-Brackmann grade II), of whom, three had recovered by the 6-month follow-up. No cases of local recurrence or malignant transformation were observed during follow-up. Conclusion: The clinical features of BCA are consistent with those of other benign tumors. The deep lobe of the parotid gland is more likely to develop BCAs, and thus, this diagnosis should be consid- ered in patients with deep-lobe tumors, especially when accompanied with cystic degeneration. FNAB can increase the rate of preoperative diagnoses.
Show more

10 Read more

Reconstruction of a subtotal upper lip defect with a facial artery musculomucosal flap, kite flap, and radial forearm free flap: a case report

Reconstruction of a subtotal upper lip defect with a facial artery musculomucosal flap, kite flap, and radial forearm free flap: a case report

Case presentation: This case report presents a man with massive midface defects, including upper lip, left nose, and cheek defects. Over the previous 2 years, the patient had three reconstructions with sequential free flaps for the resection of recurrent tumors, the first of which was in March of 2016; this resulted in the patient having massive midface defects, including an upper lip defect, a defect on the left side of the nose, and one on the left cheek. The defects were reconstructed using a radial forearm free flap (RFFF), a facial artery musculomucosal (FAMM) flap, and a kite flap. In June 2016, he underwent a second reconstruction, this time of the left nose defect, using a left anterolateral thigh (ALT) flap. In March of 2017, the patient underwent a third reconstruction with the use of a free ALT on the left intraoral cheek and the defects on the neck. All flaps survived. No complications were encountered postoperatively. The patient regained good oral sphincter function with no reports of drooling. Although the patient underwent three surgeries, the reconstruction results were acceptable.
Show more

7 Read more

Basal Cell Adenoma of the Parotid Gland: A Case Report and Review of the Literature

Basal Cell Adenoma of the Parotid Gland: A Case Report and Review of the Literature

2.Ogawa I, Nikai H, Takata T, Miyauchi M, Ito H, Ijuhin N. The cellular composition of basal cell adenoma of parotid gland: An Immunohistochemical analysis. Oral Surg Oral Med Oral Pathol1990;70(5):619-26. 3.González-García R1, Nam-Cha SH, Muñoz-Guerra MF, Gamallo-Amat C. Basal cell adenoma of the pa- rotid gland. Case report and review of the literature. Med Oral Patol Oral Cir Bucal 2006;11(2):E206-9 4.Chakravarthi S, Rao V.T, Prasad L.K, Kalyan, Kat- timani V.S. Basal Cell Adenoma – A Rare Presentation of Parotid Swelling – A Case Report and Review of The Literature. Jr.of Orofac. Scie. 2009;1(2):13-16. 5.Chawla AJ, Tan TY, Tan GJ. Basal cell adenoma of parotid gland: CT scan features Eur J Radiol 2006;58(2):260-5.
Show more

5 Read more

Basal cell carcinoma-a case report and review

Basal cell carcinoma-a case report and review

Tumours can occur on nose (32.3%), orbital (19.1%) and cheek (18.1%) regions as these areas are comparatively more exposed to sunlight 1,5,6,7 . Lesions of frontotemporal, scalp and auricular region are more common in men, which can be due to short hair or androgenic alopecia, perioral lesions especially more on the upper lip are found to be less in men 1,4 . BCC is more prevalent in 6 th and 7 th decade with the mean age of occurrence being 62 years 1 . In the last decade incidence of BCC has substantially increased and also shows geographical variations. The size of the lesion may vary from 0.2 mm to 9 cm with a mean size of 2 cm. Clinical subtypes seen are nodular, superficial, fibroepithelial and morpheaform 1,2,3 . The most frequently occurring subtype is the nodular variety 6 .
Show more

5 Read more

Original Article Expression of MYB protein and its clinicopathological significance in adenoid cystic carcinoma of salivary gland

Original Article Expression of MYB protein and its clinicopathological significance in adenoid cystic carcinoma of salivary gland

cells. In some cases, MYB expression was observed in the lymphocytes or fibroblasts of mesenchyme, but was not considered as posi- tive. The 20 samples of salivary glands adja- cent to ACC were all negative (Figure 4). In 98 cases of ACC in salivary gland, the MYB expression was positive in 87 cases, account- ing for 88.8%. Robust MYB expression was observed in 58 cases, accounting for 59.2%. The expression of MYB was weakly positive in 29 cases, accounting for 29.6%. The 20 cases of salivary gland tissue adjacent to ACC were all negative for MYB. In 8 out of 68 cases of non- ACC neoplasm, MYB stained weakly positive, accounting for 11.8%, and the remainder were all negative (-) (Figure 5). The MYB was expressed weakly in 6 out of 20 cases of basal cell adenoma (+), accounting for 30%. The expression of MYB in 1 out of 12 cases in poly- morphic adenoma was weakly positive (+), accounting for 8.3%. In 1 out of 11 myoepithe- lioma cases, MYB was weakly positive (+), accounting for 9.3%. However, MYB was nega- tive in 10 cases of Warthin tumor, 6 cases of oncocytoma and 9 cases of basal cell carcino- ma. In the control group of 5 cases of non-neo- plastic salivary glands, MYB was negative (Table 1).
Show more

7 Read more

Palisaded encapsulated neuroma of the upper lip

Palisaded encapsulated neuroma of the upper lip

Palisaded encapsulated neuroma (PEN; solitary cir- cumscribed neuroma) is a benign and hyperplastic lesion consisting of Schwann cells. PEN of the lower lip was reported by Tomich and Moll [1] 35 years ago. However, the accumulation of the information about PEN which occurred in the oral mucosa was not enough. This article describes a case of a PEN on the upper lip of a 41-year-old woman. The lesion with 0.7 cm diameter was performed excisional biopsy. His- tologically, the tumor was almost circumscribed by thin fibrous capsule, and consisted of diffusely and dense proliferation of the spindle shape cells arranged in interlacing fascicles. Focal suggestions of nuclear palisaded growth were indicated within the tumor. Immunohistochemicallly, the fascicles of tumor cells were positive for S-100 protein, and vimentin and negative for α-actin and GFAP. A few numbers of axons were demonstrated by anti-neurofilament an- tibody in this lesion. Therefore, the definitive diagno- sis was PEN.
Show more

6 Read more

Basal Cell Adenoma of the Parotid Gland: MR Imaging Findings with Pathologic Correlation

Basal Cell Adenoma of the Parotid Gland: MR Imaging Findings with Pathologic Correlation

Few imaging findings of BCA of the parotid gland have been reported. 6-9 In our cases, the morphology of BCAs was a well-defined margin and rounded contour, as with cases in previous reports. High-grade malignant tumors can easily be differentiated from BCAs by the infiltrative margins of malig- nant tumors. The differential diagnosis of BCA includes pleo- morphic adenoma, Warthin tumor, and low-grade malignant tumors. Most pleomorphic adenomas have an area containing abundant fibromyxoid stroma, which shows bright SI on T2WI as well as marked enhancement on postcontrast images. These areas show delayed enhancement on dynamic study. In addition, pleomorphic adenomas show lobulated contours and typically have a thick capsule. 9-11 These characteristic MR
Show more

5 Read more

Basal Cell Adenoma of Palate, a Rare Occurrence with Review of Literature

Basal Cell Adenoma of Palate, a Rare Occurrence with Review of Literature

Kleinsasser and Klein (1967) first used the term basal cell adenoma to describe an encapsulated, slow growing, merely epithelial neoplasm composed of dis- cernible basal cells arranged in the form of solid sheets or nests and trabecular/ tubular cord like pattern. [3] The most common site of occurrence is the parotid gland [4- 5] followed by upper lip with a decreasing incidence in palate, buccal mucosa and lower lip. [4] It usually oc- curs in patients over 50 years of age with slight female predilection. [6] Concerning its Clinical presentation, it exhibits as a slow growing, asymptomatic, movable, round or oval, normal-colored sub mucosal mass meas- uring less than 3 cm in diameter. [4]
Show more

5 Read more

Visor flap for total upper and lower lip reconstruction: a case report

Visor flap for total upper and lower lip reconstruction: a case report

Gousheh et al. used occipital scalp island flaps for total upper lip reconstruction [15]. There is no previous report of a simultaneous total upper and lower lip reconstruc- tion, in a patient with a complete absence of lip tissue. The scalp visor flap in this patient was used to reconstruct the missing midfacial and lip tissue, as well as recreate a moustache and beard. Thus while simple to design and elevate, this flap served multiple functions, and gave invaluable solutions to otherwise technically difficult reconstructive needs in this patient. It gave an excellent color match with the remaining facial skin, provided aesthetic neo-lips, complete with a moustache and a beard, as a single unit (Figure 5). The patient and relatives found the reconstruction acceptable, but expressed a desire
Show more

5 Read more

Basal Cell Adenoma in the Parotid Gland: CT and MR Findings

Basal Cell Adenoma in the Parotid Gland: CT and MR Findings

Grossly, basal cell adenomas are round or oval in shape. They tend to be smaller than pleomorphic adenomas; most measure 3 cm or less in diameter. On cut section, they are typically uniform and solid, with- out necrosis. They can, however, occasionally be cys- tic. They have characteristic, numerous endothelial- lined vascular channels, in which small capillaries and venules are prominent within the microcystic areas of the adenoma. These vascular structures can cause intratumoral hemorrhage (1, 8). The membranous type is noteworthy in that it can be multifocal, with a multinodular growth pattern. In many cases, cystic formations containing mucinous fluid are present in the center of a tumor. This can explain why basal cell adenomas are well enhanced and why hemorrhagic components are found within the cystic portion.
Show more

5 Read more

Basal cell adenocarcinoma of the salivary gland: a morphological and immunohistochemical comparison with basal cell adenoma with and without capsular invasion

Basal cell adenocarcinoma of the salivary gland: a morphological and immunohistochemical comparison with basal cell adenoma with and without capsular invasion

invasion that showed focal positivity for CK5/6, all 26 remaining BCNs expressed CK5/6 with a diffuse pattern (Table 4). Some cases expressed CK5/6 more strongly in peripherally located cells. Although all 10 ACCs also expressed CK5/6, the positivity was mostly focal, and mainly in the inner epithelial cells. This is interesting be- cause CK5/6 is a myoepithelial/basal marker. The BCNs not only differed from the ACCs in terms of CK5/6 ex- pression, they also differed in nuclear β-catenin and S100P protein expression. Thus, nuclear β-catenin was expressed by 70–100% of the BCNs (Figure 2D) and 0% of the ACCs, and S100P protein was expressed by 0–10% of the BCNs but by 50% of the 10 ACCs (Figure 2E). With regard to CD117, 57%, 60%, 100%, and 100% of the BCAC, BCA with capsular invasion, BCA without capsu- lar invasion, and ACC cases expressed this marker, re- spectively (Figure 2F). However, this marker exhibited focal CD117 expression in most BCNs whereas all ACCs diffusely expressed CD117. In terms of p53, while only 3 of the 27 BCNs (11%) were focally positive for this marker, 6 of 10 ACCs (60%) were positive for it. Moreover, in all ACCs, the Ki-67 labeling index exceeded 5% whereas most BCNs had a low ki-67 labeling index (< 5%). All BCNs and ACCs expressed VEGF, while none expressed c-erbB2.
Show more

8 Read more

Basal cell lesions of maxillofacial region

Basal cell lesions of maxillofacial region

gland sites, followed by an upper lip and buccal mucosa. (Kratochvil, 1991) Microscopically BCAs are encapsulated and well-circumscribed tumors. The cystic formation can be seen. Two types of cells are present luminal cells and basal cells. Component of the basal cell is the important diagnostic criteria. Round to oval small tumor cells are present in less cytoplasm. The nucleus is generally darkly stained which gives the basaloid appearance. In two cell types, basaloid cells are present periphery to the luminal cells or tumor cells. In nests of basaloid cells, cuboidal or columnar cells which are present in the outer layer have a tendency of palisaded arrangement. There is a sharp boundary between stroma and tumor cells. Stroma is thin and vascular activity is rarely seen. (Salivary gland tumor pathology. Irving Dardick) Tubular type microscopically shows tumor cells are present in cords and they are interconnected and contain duct or acinar-like structures. Lumens are present within the cords and contain secretions. The outer layer consists of single and smaller cells and slightly larger central cells responsible for lumen formation. The thin stromal tissue is present in between the cords of tumor cells. (Salivary gland tumor pathology. Irving Dardick) Trabecular type microscopically shows two or more cells thick narrow interconnecting cords. Tumor cell cords are uniform in thickness. The central portion of trabeculae shows larger cells with increased cytoplasm. Lumens are smaller in size or absent. (Salivary gland tumor pathology. Irving Dardick) Solid type microscopically shows tumor cells are present in the nests and these nests are bulbous, closely associated, variable in shape and angular. And arrangements of these nests are complex. Peripheral cells
Show more

5 Read more

A Study on Knowledge, Perceptions and Attitudes about Screening and Diagnosis of Diabetes in Saudi Population

A Study on Knowledge, Perceptions and Attitudes about Screening and Diagnosis of Diabetes in Saudi Population

In the present study, we have aspirated 84 cases of parotid swelling. In 78 cases aspiration produced adequate material and in six cases, materials were inadequate even after repeated aspiration. We found 45 male patients (53.57%) and 39 female cases (46.43%) in the study group. Patients ranged in age from 8 years to 71 years with a mean age of 38.73 years. Age distribution reveals large number of cases in the age group of 21-50 years. (Figure 1) Mean age of malignant cases (53.14years) was higher than benign cases (38.19 years). In the present study, four cases (5.12%) were bilateral. We found most of the cases were benign (40 cases, 51.28%) and non-neoplastic (23 cases, 29.48%); whereas only 14 cases (19.23%) were malignant. (Table 1) Among the non-neoplastic cases, most common lesion was chronic sialoadenitis (20 cases). Among the benign parotid swellings PSA was the commonest subtype (30 cases, 38.46%). Other benign parotid tumors diagnosed are warthin’s tumor (6 cases), monomorphic adenoma (3 cases) and oncocytoma (one case). [Table 1] Most common malignant parotid tumor in our study was mucoepidermoid carcinoma (5 cases, 6.41%). Other malignancies were adenoid cystic carcinoma, acinic cell carcinoma and salivary duct carcinoma etc. We found single case of non-Hodgkin’s lymphoma, pleomorphic adenoma ex carcinoma and metastatic melanoma respectively in the present study group. [Table 1]
Show more

6 Read more

ISLET CELL ADENOMA IN CHILDHOOD: REPORT OF A CASE

ISLET CELL ADENOMA IN CHILDHOOD: REPORT OF A CASE

The findings of hypoglycemia precipitated by fasting, hypoglycemia regu- lanly induced following oral glucose inges- tion, and the pathological response to intra- venous tolbutamide are [r]

11 Read more

-Oids: An Insight

-Oids: An Insight

Dermoid cysts (when skin adnexa are found in the cyst wall) are cystic malformations with squamous epithelial lining (Fig. 11). Of all cysts in the head and neck area, dermoid cysts constitute 1.6 to 6.9%. Their aspirates contain additional elements as the walls of the cysts have hair follicles and sebaceous and sweat glands. When the dermoid cyst ruptures, it might induce an inflammatory and multinucleated giant cell response as these cysts are filled with grumous keratinaceous material and can be demonstrated on the smears. Inflamed cysts can also reveal focal reactive atypia of the squamous epithelium. The smears show the presence of benign-appearing squa- mous cells, anucleated squamous cells, and amorphous debris and also show sheets of large, benign-appearing anucleated and nucleated squamous cells, when second- ary inflammation is present. Inflammatory infiltrate with large numbers of neutrophils are seen, but the majority of cells show no evidence of atypia. The cytologic material of dermoid and epidermoid cysts seems to be similar. 17-19
Show more

12 Read more

A Model of a Tunnel and a Simulation of Ventilation in the Case of Fire

A Model of a Tunnel and a Simulation of Ventilation in the Case of Fire

Any temperature curve is the result of a fire scenario and cannot act as a basic design requirement unless a worst-case-based fire curve is chosen. The analyses and simulations show remarkable differences for the different tunnels. The temperature range can be between 800 °C and more than 1300 °C. The initial phase offering the possibility of escape is very limited. Temperatures exceeding 1000 °C together with the smoke concentration provide conditions where the chances of survival are close to zero. The surrounding walls in a tunnel together with the lack of heat escape in the vertical direction, lead to a large temperature increase in just a few minutes.
Show more

11 Read more

An Evaluation of the Attractiveness of A Posed Smile with Computerised Variations of the Smile Parameters

An Evaluation of the Attractiveness of A Posed Smile with Computerised Variations of the Smile Parameters

for more upward curvature of upper lip during smile . For smile arc wherein lower lip was kept slightly touching upper incisors, a very highly significant difference was found between the ratings of uneducated females and dental professionals. A very highly significant difference was found between the ratings of dental professionals and other judges for smile arc wherein lower lip was placed 1mm below upper incisors.For a medium broad (10%) buccalcorridor,a very highly significant difference was found between the ratings of educated

5 Read more

Show all 10000 documents...

Related subjects