[PDF] Top 20 Changes in circulating microRNA levels associated with prostate cancer

... non-metastatic prostate cancer cohort, 77 samples characterised as either M0 or M1 were assayed by individual Taqman qRT – PCR for five miR markers (miRs 375, 107, 200b, 141 and 452) found to have either ... See full document

... morphological changes associated with altered cytoskeletal dynamics, which included impairing mitochondrial movement and actin polymerization ...impair cancer cell invasiveness in a breast ... See full document

... the changes in ATF2 protein level in C4–2 ...protein levels, suggesting that the SPOP-E3 ubiquitin ligase complex is required for the degradation of ...different levels of SPOP-WT, SPOP-ΔBTB or ΔMATH ... See full document

... CIC levels in sera of PCa and BPH are significantly elevated in comparison with the levels of normal subjects ...increased levels of CIC obtained with the grades of disease suggest that the CIC is ... See full document

... Prostate cancer (PCa) is the most common urological cancer, which accounts for more than 20% of men’s malignant ...was associated with a higher risk of PCa detection as an inde- pendent factor ... See full document

... are associated with prostate ...previously associated with bio- marker levels (8 from a genome-wide association study [GWAS] and 48 in reported candidate ...without prostate ... See full document

... previously associated with biomarker levels (8 from a genome-wide association study [GWAS] and 48 in reported candidate ...without prostate cancer and two replication cohorts (N~900 and ... See full document

... is associated with mental disorders, such as bipo- lar disorder, schizophrenia, and major depressive disorder ...study, circulating miR-144* level chan- ged with stress associated with the nationally ... See full document

... in prostate oncogenesis ...and associated necrosis could also promote IL release ...of prostate cancerogenesis, in this study we evaluated IL gene expression and protein production at local and ... See full document

... purpose: MicroRNA-128 (miR-128) has been identified as a negative regulator of malig- nant phenotypes of prostate cancer (PCa) ...serum levels of miR-128 expression in PCa patients undergoing ... See full document

... was associated with poor response to chemotherapy and targeted therapy (cetuximab combined with irinotecan) [17], which was similar to our ...miR-345 levels were strongly correlated with poor pathological ... See full document

... Bladder cancer (BCa) is one of the leading cancers in urinary ...serum levels of omentin-1 and adiponectin altered not only upon the conditions with insulin resistance, but also associated with ... See full document

... miR-486 levels between patients with heart failure and ...measuring circulating miR-486 levels in breast cancer ...expression levels of miR-486 and miR-146a were converted to ... See full document

... Liquid biopsy is a fast-evolving fi eld with the potential to change patient management across a broad spectrum of cancer types, including PC. Until now, CTC enumerated by CellSearch has been by far the best ... See full document

... microRNAs associated with HNSCC metastasis, Liu et ...pathways associated with epithelial- mesenchymal-transition (EMT), thereby gaining the ability to migrate and ...the cancer cells to survive ... See full document

... of cancer care is exploding, particularly due to new targeted ...of cancer is between 4-6 % of the healthcare spending, cancer drugs account for approximately one third of the costs and this spending ... See full document

... be associated with short- er OS by univariate Cox proportional hazards regression, while no independent predictive factors for OS were found by multi- variate ... See full document

... Overall, the results from these studies have been inconclusive, some studies have shown a mildly increased risk [14, 8, 13, 12] whereas other studies have demonstrated a[r] ... See full document

... clear evidence for the value in combining prognostic bio- markers with targeted therapies. Even though early detec- tion and targeted therapies have significantly lowered breast cancer-related mortality rates, ... See full document

... (metastatic) prostate cancer; mCRPC; circulating tumor cells; CTC; CTC trap; Circulating Tumor Cells therapeutic aphaeresis; therapy monitoring; management; medical technology; health ... See full document