[PDF] Top 20 Characterization of and Functional Antigen Presentation by Central Nervous System Mononuclear Cells from Mice Infected with Theiler’s Murine Encephalomyelitis Virus
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Characterization of and Functional Antigen Presentation by Central Nervous System Mononuclear Cells from Mice Infected with Theiler’s Murine Encephalomyelitis Virus
... shielded from the systemic circulation by a specialized contin- uous vascular endothelium ...specialized cells with- in the CNS with the potential to present antigens to T ...culture cells ... See full document
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Epitope-Tagged L* Protein of Theiler's Murine Encephalomyelitis Virus Is Expressed in the Central Nervous System in the Acute Phase of Infection
... glial cells [15]), whereas DA was detected not only in neurons but also in astrocytes and possibly in macrophages/ microglial cells by in situ hybridization-immunostaining assay ...SJL/J mice ... See full document
6
The Role of Interleukin-6 in the Expression of PD-1 and PDL-1 on Central Nervous System Cells following Infection with Theiler's Murine Encephalomyelitis Virus
... SJL mice and resistant B6 mice, as well as the viral infection-induced signals associated with the expres- ...T cells and potential antigen-presenting cells in the periphery and the CNS ... See full document
14
Functional Expression of Chemokine Receptor CCR5 on CD4+ T Cells during Virus-Induced Central Nervous System Disease
... the central nervous system (CNS), in response to viral infection, is important in host defense by eliminating infectious virus through either secretion of antivi- ral cytokines or killing of ... See full document
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Central nervous system Toll like receptor expression in response to Theiler's murine encephalomyelitis virus induced demyelination disease in resistant and susceptible mouse strains
... SJL/J mice. That would appear to be central in the enhanced response by the susceptible mice is the intensity of the TLR ...immune cells, it could increase their susceptibility to ... See full document
9
Mode of spread to and within the central nervous system after oral infection of neonatal mice with the DA strain of Theiler's murine encephalomyelitis virus.
... differences from the general pattern previously reported to occur after ...different from that reported after ...limbic system (3, ...the virus in different regions of the ...viral ... See full document
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Differences in Avidity and Epitope Recognition of CD8+ T Cells Infiltrating the Central Nervous Systems of SJL/J Mice Infected with BeAn and DA Strains of Theiler's Murine Encephalomyelitis Virus
... Theiler’s murine encephalomyelitis virus (TMEV) infection induces immune-mediated demyelinating dis- ease in susceptible mouse strains and serves as a relevant infectious model for human multiple ... See full document
5
Direct evidence of a role for amino acid 101 of VP-1 in central nervous system disease in Theiler's murine encephalomyelitis virus infection.
... For viral antigen, cytoplasmic extracts from cells infected with DAFL3, OSM101, the H7A6-2 variant, or the parental DA virus were used.. In this study, two antibodies were used, MAb H7 a[r] ... See full document
9
Critical Role for Protein Tyrosine Phosphatase SHP-1 in Controlling Infection of Central Nervous System Glia and Demyelination by Theiler's Murine Encephalomyelitis Virus
... of virus-induced demyelinating dis- ease, infection often involves astrocytes and oligodendrocytes in the white matter in the vicinity of demyelinating lesions (1, 2, 18, 24, 44, 47, 49, ...by virus infec- ... See full document
12
Modeling the Acute and Chronic Phases of Theiler Murine Encephalomyelitis Virus Infection
... Theiler murine encephalomyelitis virus (TMEV) infection of a mouse’s central nervous system is biphasic: first the virus infects motor neurons (acute phase), and ... See full document
8
The Majority of Infiltrating CD8+ T Cells in the Central Nervous System of Susceptible SJL/J Mice Infected with Theiler's Virus Are Virus Specific and Fully Functional
... Theiler’s murine encephalomyelitis virus (TMEV) is a com- mon enteric mouse picornavirus ...demyelination-susceptible mice leads to eventual autoimmune responses against myelin au- toantigens ... See full document
9
Alphavirus-Induced Encephalomyelitis: Antibody-Secreting Cells and Viral Clearance from the Nervous System
... Infectious virus and virus RNA ...prepared from the whole spinal cord ...infectious virus by plaque formation on BHK cells. RNA was isolated from the whole spinal cord and half ... See full document
12
Targeting of prion-infected lymphoid cells to the central nervous system accelerates prion infection
... immune cells of prion-infected mice. Such PrP Sc -rich cells may then be targeted by CNS inflamma- tion for infiltration into the CNS, as demonstrated by the presence of PrP Sc deposits in ... See full document
8
Detection of Coronavirus in the Central Nervous System of a Child With Acute Disseminated Encephalomyelitis
... rose from 1:160 in acute serum to 1:640 in convalescent serum (3 weeks ...syncytial virus, parainfluenza virus, influenza virus, and ...syncytial virus, my- coplasma, influenza viruses, ... See full document
6
Functional applications of CT of the central nervous system
... spatial resolution and rapid scanning time 1-10 sec are important advantages of x-ray CT over other imaging methods, particularly when analyzing cerebral perfusion, Reasonably accurate i[r] ... See full document
16
Identification and Functional Characterization of a New Splicing Variant of EZH2 in the Central Nervous System
... invariable regions I1-I4 (Fig. 1A). In comparison with EZH2-WT, V3 was skipped during the mRNA processing to generate X9, a variant structurally distinct from any other transcripts. According to the sequence ... See full document
12
Identification of an FMR cell surface antigen associated with murine leukemia virus-infected cells.
... It was concluded from these studies that the FMuLV and EdG2 leukemia cells contained on their cell surface the viral envelope protein gp7O and the glycosylated polyprotein precursors of [r] ... See full document
8
Identification of the Gross cell surface antigen associated with murine leukemia virus-infected cells.
... This is demonstrated by the following: i the GCSA typing serum predominantly precipitates 85,000- and 95,000-dalton proteins from 1251-labeled C57BL/6 Ed G2 membrane preparations, ii the[r] ... See full document
8
Ceruloplasmin gene expression in the murine central nervous system
... of murine and human ceruloplas- min reported here implies species conservation of function and suggests that these findings will be relevant to understanding the role of ceruloplasmin in human iron ...multiple ... See full document
10
Characterization of La Crosse Virus RNA in Autopsied Central Nervous System Tissues
... LAC virus is distributed throughout the eastern half of the United States (5, ...LAC virus occur frequently (11); however, less than 1.5% of LAC virus infec- tions are clinically apparent (11, ...the ... See full document
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