[PDF] Top 20 10′ Chloro 3′,4′ dihydro 2′H spiro[cyclopropane 1,7′(6′H) pyrimido[2,1 a]isoquinolin] 6′ one
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10′ Chloro 3′,4′ dihydro 2′H spiro[cyclopropane 1,7′(6′H) pyrimido[2,1 a]isoquinolin] 6′ one
... As an extension of our work to develop complex heterocyclic skeletons as leads for potential pharmaceutical agents (Okuda et al., 2011), we found that tricyclic 5-amino-1,2-dihydrofuro[2,3-c]isoquinolines (Okuda et al., ... See full document
8
10′′ (4 Chlorobenzylidene) 5′′ (4 chlorophenyl) 4′ (2,4 dichlorophenyl) 1′ methyl 2,3,2′′,3′′,7′′,8′′,9′′,10′′ octahydro 1H,5′′H,6′′H indole 3 spiro 2′ pyrrolidine 3′ spiro 2′′ cyclohepteno[1,2 d]thiazolo[3,2 a]pyrimidine 2,3′′ dione
... + 2] cycloaddition of azomethine ylide, derived from isatin and sarcosine by a decarboxylative route, and 5-(4- chloro)phenyl-10-(4-chloro)benzylidene-2-(2,4-dichloro)- ... See full document
16
10′′ (4 Methoxybenzylidene) 5′′,4′ bis(4 methoxyphenyl) 1′ methyl 2,3,2′′,3′′,7′′,8′′,9′′,10′′ octahydro 1H,5′′H,6′′H indole 3 spiro 2′ pyrrolidine 3′ spiro 2′′ cyclohepteno[1,2 d]thiazolo[3,2 a]pyrimidine 2,3′′ dione
... two spiro junctions link a planar 2-oxindole ring, a pyrrolidine ring in an envelope conformation and a 10-(arylmethylene)hexahydrocyclohepta[1,2-d]thiazolo- [3,2-a]pyrimidin-3-one ... See full document
14
4′ (4 Methoxyphenyl) 1′ methyl 4′′,5′′,6′′,7′′ tetrahydro 1H indole 3 spiro 2′ pyrrolidine 3′ spiro 2′′ (thiazolo[3,2 a]pyrimidine) 2(3H),3′′(2′′H) dione
... of spiro-compounds (Caramella & Grunanger, ...+ 2]-cycloaddition of azomethine ylide, derived from isatin and sarcosine by a decarboxylative route, and 2-(4-methoxy-benzylidene)-6,7- ... See full document
11
4′ (4 Chlorophenyl) 1′ methyl 4′′,5′′,6′′,7′′ tetrahydro 1H indole 3 spiro 2′ pyrrolidine 3′ spiro 2′′ (thiazolo[3,2 a]pyrimidine) 2(3H),3′′(2′′H) dione
... + 2]-cycloaddition of azomethine ylide, derived from isatin and sarcosine by a decarboxylative route, and 2-(4-chlorobenzylidene)-6,7-dihydro-5H-thiazolo[3,2-a]- ...two spiro junctions link a ... See full document
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Hydrogen bonding in 1′ nitro 2′ phenyl 2′,3′,4′,5′,6′,7′ hexahydro 1H indole 3 spiro 3′ 1′H pyrrolizidin 2(3H) one: molecular chains built from alternating (18) and (8) rings
... A mixture of nitrostyrene (1 mmol), isatin (1 mmol) and proline (1 mmol) in methanol (20 ml) was refluxed until the disappearance of starting materials. After completion of the reaction, the reaction ... See full document
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1′,5 Dinitro 2′ phenyl 2′,3′,5′,6′,7′,7a' hexahydrospiro[indoline 3,3′ 1′H pyrrolizin] 2 one
... g, 1 mmol), proline (0.115 g, 1 mmol), and trans-β-nitrostyrene ...g, 1 mmol) in ethanol (10 ml) was stirred at refluxed for 1 ... See full document
9
Cyclohexanespiro 2′ [2′,3′,6′,7′ tetrahydro 1′H cyclopenta[d]pyrimidin] 4′(5′H) one
... (Fig. 1) are linked by N1—H···O1 and N2—H···O1 H-bonds , as shown in ...Fig. 2 and have a similar conformation as ... See full document
7
1 [2 Oxo 1′ phenyl 2′,3′,5′,6′,7′,7a' hexahydroindoline 3 spiro 3′ 1′H pyrrolizin 2′ yl] 3 phenylprop 2 en 1 one
... A solution of (1E,6E)-4-benzylidene-1,7-diphenylhepta-1,6-diene-3,5-dione (1 mmol), isatin (1 mmol) and L-proline (1 mmol) in aqueous methanol (20 ml) was refluxed until the disappearance of ... See full document
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2′ (2 Chlorophenyl) 1′ nitro 2′,3′,4′,5′,6′,7′ hexahydro 1H indole 3 spiro 3′ 1′H pyrrolizin 2(3H) one
... Bond lengths and bond angles of the pyrrolizidine group and the oxindole unit present no unexpected features and are in the same range as observed in reported structures (Govind et al., 2004; Usha et al., 2005). The C9 ... See full document
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3 (2 Chloro 6 fluorophenyl) 1 (2 thienyl)prop 2 en 1 one
... one molecule, with corresponding values 6.09 (17) and 1.3 (6) in the other. Weak intramolecular C—H O and C—H F interactions involving the prop-2-en-1-one group generate ... See full document
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2′ Benzoyl 1′,2,2′,3,4′,5′,6′,6a′ octahydro 1H indan 2 spiro 3′ (3′H pyrrolizine) 1′ spiro 3′′ 1H indoline 1,2′′,3 trione
... In addition to van der Waals interactions, the crystal structure is stabilized by intermolecular CÐH O hydrogen bonds. In the crystal structure, symmetry-related molecules are linked by CÐH and NÐH O intermolecular ... See full document
10
(2E) 1 (6 Chloro 2 methyl 4 phenylquinolin 3 yl) 3 (4 chlorophenyl)prop 2 en 1 one
... configuration about the ethylene double bond, they differ in the relative orientations of the carbonyl and ethylene double bonds within the prop-2-en-1-one residues, i.e. anti and syn. For each ... See full document
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[1]; [2]; [3]; [4]; [5]; [6]; [7] . In regards to this, the
... Table 1 provides principal component solution of feeling toward promotion. It’s constructed six (6) dimensions. Promising, attractive, convinced, hopeful, inspire, interested, decent, and satisfied are ... See full document
5
1 Acetyl 3 ethyl r 2,c 6 di 2 furylpiperidin 4 one
... In the paper by Balamurugan, Thiruvalluvar, Manimekalai, Selvaraju & Maruthavanan [Acta Cryst. (2006), E62, o2005– o2006], the two first sentences in the Abstract contain errors. The correct text is "In the title ... See full document
10
2′ (4 Bromobenzoyl)acenaphthene 1 spiro 3′ pyrrolizidine 1′ spiro 3′′ indole 2,2′′(1H,3′′H) dione monohydrate
... C17 0.060 (3) 0.064 (2) 0.073 (3) 0.001 (2) 0.009 (2) −0.027 (2) C18 0.063 (3) 0.054 (2) 0.055 (2) −0.007 (2) −0.004 (2) −0.0096 (17) C19 0.057 ... See full document
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1 Benzoylacenaphthylene 1 spiro 3′ pyrrolizidine 2′ spiro 3′′ 1H indole 2,2′′(1H,3′′H) dione
... (Table 2). Keto atom O36 is 0.521 (3) AÊ out of the plane through C4/C14/C16/C20, with the C14 O36 bond orientation de®ned by the torsion angles O36ÐC14Ð C15ÐC20 = ... See full document
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... [r] ... See full document
66
(6′R*,7′R*) 7′ (1,3, Diphenyl 1H pyrazol 4 yl) 1,2,5′,6′,7′,7a',3′′,4′′ octahydro 1′H,2′′H dispiro[acenaphthylene 1,5′ pyrrolo[1,2 c][1,3]thiazole 6′,3′′ [1]benzopyran] 2,4′′ dione
... C40 0.0441 (8) 0.0592 (11) 0.0570 (10) 0.0251 (8) 0.0100 (8) 0.0345 (9) N1 0.0489 (7) 0.0314 (6) 0.0330 (6) 0.0123 (5) 0.0004 (5) 0.0162 (5) N2 0.0503 (7) 0.0354 (7) 0.0342 ... See full document
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4′ (4 Chlorophenyl) 3′' ethyl 1′ methyl 1H indole 3 spiro 2′ pyrrolidine 3′ spiro 5′′ [1,3]thiazole 2(3H),2′′(3′′H),4′′(5′′H) trione benzene sesquisolvate
... conformation; atom N2 is displaced by 0.618 (3) Å from the mean plane of the C5/C4/C3/C6 atoms [plane A; maximum deviation of the C4 atom is 0.031 (3) Å]. The C5/N2/C6 plane forms a dihedral angle of 135.6 ... See full document
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