[PDF] Top 20 Clonal relationships in recurrent B-cell lymphomas
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Clonal relationships in recurrent B-cell lymphomas
... of clonal relationships between primary and corresponding relapsed tumors, based on analysis of the rearranged Ig ...each B-cell type and is highly conserved during the clonal expansion ... See full document
13
53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis
... thymic lymphomas, and, based on this finding, we propose that tumorigenesis in 53BP1 ⫺/⫺ 兾 p53 ⫺/⫺ T cells pro- ceeds through either of two separate mechanisms: aneuploidy and clonal ...thymic ... See full document
7
Genetic pathway to recurrent chromosome translocations in murine lymphoma involves V(D)J recombinase
... non-Hodgkin’s lymphomas in ...of B-lineage lymphomas has been observed in mice with severe combined immunodeficiency (SCID) and p53-null ...harbor recurrent translocations involving ... See full document
8
A splenic IgM memory subset with antibacterial specificities is sustained from persistent mucosal responses
... 2018). Clonal relationships were also described between gut IgA plasma cells and spleen memory B cells (Lindner et ...assess relationships of peripheral B cells to mucosal immune ... See full document
19
Clonal relationships of CSF B cells in treatment-naive multiple sclerosis patients
... Ig-RepSeq. Total RNA was extracted from sorted B cell subsets (RNeasy Micro Kit, Qiagen) and reverse transcribed (iScript cDNA Synthesis Kit, Bio-Rad). PB and CSF cDNA was used for IgM-VH and IgG-VH ... See full document
17
Common Viral Integration Sites Identified in Avian Leukosis Virus Induced B Cell Lymphomas
... B and has known roles mediating apoptosis and regulating inflammation and cell proliferation ...increased clonal expansion of the cells carrying that ... See full document
11
The predictive significance of CD20 expression in B-cell lymphomas
... or recurrent lymphoma at the Institute of Oncology Ljubljana, Slovenia between 2003 and 2007 were included in the ...or recurrent lymphoma had been suspected ...mantle cell lymphoma (MCL) and 15 ... See full document
6
Human herpesvirus–encoded kinase induces B cell lymphomas in vivo
... poly- clonal vPK antibody (83) that was provided by Hsing-Jien Kung and Yoshihiro Izumiya (UCD School of Medicine, Sacramento, Califor- nia, USA), followed by an HRP-linked, anti-rabbit IgG secondary antibody ... See full document
17
An unusual case of Epstein-Barr virus-positive large B-cell lymphoma lacking various B-cell markers
... additional B- cell markers. Expression of B-cell-specific transcription factors detected by additional IHC and clonal re- arrangement of the immunoglobulin genes confirmed our final ... See full document
6
Rearrangement of the beta chain of the T cell antigen receptor and immunoglobulin genes in lymphoproliferative disorders
... lymphoepitheloid cell (Lennert's) lymphomas; four of eight Hodgkin's lymphomas; seven of ten Ki 1+ lymphomas; and all nine cases of angioimmunoblastic lymphoadenopathy ...lymphoepitheloid ... See full document
7
Combined deletion of Xrcc4 and Trp53 in mouse germinal center B cells leads to novel B cell lymphomas with clonal heterogeneity
... peripheral B cells resulted in the devel- opment of surface Ig negative lymphomas from editing and switching B cells (termed CXP lymphomas) ...mature B cell characteristics, they ... See full document
14
Deep sequencing reveals clonal evolution patterns and mutation events associated with relapse in B cell lymphomas
... each B cell and its progeny ...tion, B cells further introduce point mutations into the recombined VDJ sequences, a process known as somatic hypermutation (SHM), to enhance antibody affinity ... See full document
17
The IgH 3’ regulatory region influences lymphomagenesis in Igλ-Myc mice
... The IgH 3’regulatory region (3’RR), encompassing the four transcriptional enhancers hs3a-hs1,2-hs3b-hs4, has a key role on class switch recombination, somatic hypermutation, IgH transcription and B-cell ... See full document
10
The biology of tumor growth in the non Hodgkin's lymphomas A dual parameter flow cytometry study of 220 cases
... tumor cell populations with near-tetraploid DNA ...intermediate B cell lymphomas and among the aggressive T cell ...electronic cell volumes of the aneuploid ...large cell ... See full document
15
A case of enteropathy-associated T-cell lymphoma (Type I) arising in stomach without refractory celiac disease
... T cell lymphoma (EATL) is a rare primary extranodal T cell lymphoma which was thought to arise from the intraepithelial cells of the small intestines ... See full document
6
Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma
... many cell lines it appears that response to BCL6 inhibitors correlates with BCL6 levels, in that higher doses are required to suppress cell lines that express more ...firming cell line data showing ... See full document
13
T-Cell B-Rich Lymphoma Presenting as Renal Colic with Positivity of CD3 TCRBCL, CD3 positive
... this subtype was classified as a variant of Diffuse Large B-Cell Lymphoma (DLBCL), forming less than 10% of DLBCL 3 . T/HRLBCL has a male predilection, and usually presents in the fourth decade of life, ... See full document
5
Context- Dependent Gene Expression Programs Promote Lymphocyte Development and Function and Suppress Transformation
... in B and T lymphocyte development and germinal center formation, despite increased expression of cyclin D2 in affected ...cells. Cell types requiring D3 are those in which proliferation closely follows ... See full document
160
Case Report Primary thyroid T-lymphoblastic lymphoma: a case report and review of the literature
... of the neck, including hoarseness, dysphasia, and dyspnea. Imaging findings include unilat- eral nodule or mass (5/13), nodule with bilat- eral thyroid enlargement (3/13), and diffuse thyroid enlargement (5/13), which ... See full document
8
Toll-like receptors in the pathogenesis of human B cell malignancies
... enhances B-cell proliferation and plasma cell differentiation ...in B-cells was essential [13,25]. Naïve B-cells stimulated by CpG start proliferating and differentiate to IgM producing ... See full document
10
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