[PDF] Top 20 Comparative genomic analysis of multidrug-resistant <em>Streptococcus pneumoniae</em> isolates
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Comparative genomic analysis of multidrug-resistant <em>Streptococcus pneumoniae</em> isolates
... was 91,339–310,534 bp, and the N50 scaffold length was 41,305–82,460 bp. Furthermore, we observed that similar numbers of indels (range 131–171) were present in isolates exhibiting different levels and profiles of ... See full document
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<p>Structural Genomics of <em>repA, repB1</em>-Carrying IncFIB Family pA1705-<em>qnrS</em>, P911021-<em>tetA</em>, and P1642-<em>tetA</em>, Multidrug-Resistant Plasmids from<em> Klebsiella pneumoniae</em></p>
... clinical isolates belonging to K. pneumoniae were obtained from different countries including China, USA, Italy, and ...K. pneumoniae strains A1705, 911021, 1642 into A1705-qnrS-DH5 α , ... See full document
15
Evidence of Clonal Dissemination of Multidrug Resistant Streptococcus pneumoniae in Hong Kong
... -resistant Streptococcus pneumoniae isolates saved during 1994 to 1997 at the Prince of Wales Hospital and Pamela Youde Nethersole Eastern Hospital, Hong Kong, was ...these isolates to ... See full document
6
<p>Dissemination Pattern of Multidrug Resistant Carbapenemase Producing <em>Klebsiella pneumoniae</em> Isolates Using Pulsed-Field Gel Electrophoresis in Southwestern Iran</p>
... All isolates were typed using a PFGE technique based on the PulseNet One-Day (24 – 28 h) Standardized Laboratory ...the genomic DNA of E. coli isolates and ...digest genomic DNA according to ... See full document
9
Multidrug Resistant Streptococcus pneumoniae in Poland: Identification of Emerging Clones
... among Streptococcus pneumoniae isolates has rapidly emerged in Poland during the last decade and has reached prevalence levels of up to ...epidemiological analysis of ... See full document
7
Multidrug Resistant Streptococcus pneumoniae Serotype 6D Clones in South Korea
... S. pneumoniae serotype 6D isolates have been re- ported in several regions including Fiji, South Korea, China, Japan, Hong Kong, Denmark, Poland, Australia, and Peru (3, 4, 7, 12, 16, 18, 20, 21, ...6 ... See full document
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The comparative development of elevated resistance to macrolides in community-acquired pneumonia caused by <em>Streptococcus pneumoniae</em>
... S. pneumoniae isolates were non- susceptible to penicillin G, and ...were resistant to ...The analysis of quinolone resistance determined eight strains and showed that the 18 ... See full document
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<p>Phenotypic and Genomic Characterization of Virulence Heterogeneity in Multidrug-Resistant ST11 <em>Klebsiella pneumoniae</em> During Inter-Host Transmission and Evolution</p>
... antibiotic- resistant genes, representing a threat to public ...becoming resistant to the majority of available antibiotics, primarily driven by worldwide dissemination of a speci fi c ... See full document
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Community-acquired pneumonia caused by carbapenem-resistant <em>Streptococcus pneumoniae</em>: re-examining its prevention and treatment
... revealed multidrug-resistant Streptococcus pneumoniae, even to ...S. pneumoniae with the same susceptibility pattern. Analysis for resistant genes revealed gPRSP (pbp1a + ... See full document
5
Comparative analysis of the pathogenicity between multidrug-resistant <em>Acinetobacter baumannii</em> clinical isolates: isolation of highly pathogenic multidrug-resistant <em>A. baumannii</em> and experimental therapeutics with fourth-generation cephalosporin cefozopran
... (PFGE) isolates were tested in the ...baumannii isolates resulted in time-dependent and dose-dependent larval death, but LD 50 values varied mark- edly (Table ...(MDRA) isolates (Figure 1). The LD 50 ... See full document
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Emerging resistant serotypes of invasive<em> Streptococcus pneumoniae</em>
... The isolates used in this study were collected from patients attending Hamad Hospital and emergency clinics at Hamad Medical Corporation, Qatar, during the period between January 2005 and March ...S. ... See full document
8
Molecular Epidemiology of Macrolide Resistant Streptococcus pneumoniae Isolates in Europe
... Two serotypes (23F and 14) were identified by the present investigation as major contributors to the emergence of mac- rolide resistance in Europe. MLST, combined with recent de- velopments in high-throughput sequencing ... See full document
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<p>Risk Factors for Subsequential Carbapenem-Resistant <em>Klebsiella pneumoniae</em> Clinical Infection Among Rectal Carriers with Carbapenem-Resistant <em>Klebsiella pneumoniae</em></p>
... CRKP isolates produced KPC carbapenemase, with one isolate co-producing both KPC and NDM, and one isolate co-producing both KPC and ...CRKP isolates originated from clinical infection sites also produced ... See full document
7
Molecular characterization of clinical multidrug-resistant Klebsiella pneumoniae isolates
... Enterobacteriaceae such as Escherichia coli and K. pneu- moniae [19], the even higher prevalence of blaCTX-M among our strains corresponds with an earlier report showing that CTX-M–producing strains are generally MDR ... See full document
5
<p>Molecular Epidemiological Insights into Colistin-Resistant and Carbapenemases-Producing Clinical <em>Klebsiella pneumoniae</em> Isolates</p>
... In conclusion, infections with carbapenem-resistant organisms, particularly when KPC-producing, are widely distributed, and antimicrobial treatments selected should be critically evaluated, since an optimal ... See full document
13
<p>Sputum <em>Streptococcus pneumoniae</em> is reduced in COPD following treatment with benralizumab</p>
... load. Analysis of sputum samples of COPD patients participating in a Phase II trial of benralizumab indicated that sputum 16S rDNA load and Streptococcus pneumoniae were reduced following treatment ... See full document
9
Phage Resistance in Multidrug Resistant Klebsiella pneumoniae ST258 Evolves via Diverse Mutations That Culminate in Impaired Adsorption
... to resistant outgrowth between coincidentally evolved and sequentially evolved P1 ⫹ P2-resistant mutants, suggesting the presence of a significant inoculum ... See full document
14
Direct sequencing for rapid detection of multidrug resistant <em>Mycobacterium tuberculosis</em> strains in Morocco
... of multidrug resistant (MDR) and extensively drug resistant (XDR) TB cases has worsened the situation, raising concerns of a future epidemic of virtually untreatable ... See full document
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<p>Potential role of the antimicrobial peptide <em>Tachyplesin III</em> against multidrug-resistant <em>P. aeruginosa</em> and <em>A. baumannii</em> coinfection in an animal model</p>
... Histological analysis show that, in contrast to WT mice, bacterial infection induced histological lung injury and the coinfection group presented the most serious ... See full document
10
Evaluation of the GenoType MTBDR<em>plus</em> and MTBDR<em>sl</em> for the detection of drug-resistant <em>Mycobacterium tuberculosis</em> on isolates from Beijing, China
... In order to rapidly detect MDR-TB and XDR-TB, WHO endorsed line probe assays (LPAs) of MTBDRplus and MTB- DRsl for the detection of RFP, INH, FQ, SLID, and EMB resistance in acid-fast bacilli smear-positive sputum or MTB ... See full document
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