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[PDF] Top 20 A comparison of early versus late initiation of renal replacement therapy for acute kidney injury in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials

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A comparison of early versus late initiation of renal replacement therapy for acute kidney injury in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials

A comparison of early versus late initiation of renal replacement therapy for acute kidney injury in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials

... Artificial Kidney Initiation in Kidney Injury (AKIKI) trial demonstrated that mortality at 60 days was compar- able between the groups ...the early-strategy group and ...ELAIN ... See full document

14

A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta analysis

A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta analysis

... in patients with AKI were selected for further ...Full-text review was independently performed by two reviewers (as above) for the following specific elig- ibility criteria: 1) observational cohort and/or ... See full document

10

Earlier versus later initiation of renal replacement therapy among critically ill patients with acute kidney injury: a systematic review and meta-analysis of randomized controlled trials

Earlier versus later initiation of renal replacement therapy among critically ill patients with acute kidney injury: a systematic review and meta-analysis of randomized controlled trials

... Although renal replacement therapy (RRT) remains the primary supportive management strategy for patients with severe AKI, it could also be associated with com- plications and adverse events ... See full document

14

Early versus late initiation of renal replacement therapy in patients with acute kidney injury-a systematic review & meta-analysis of randomized controlled trials

Early versus late initiation of renal replacement therapy in patients with acute kidney injury-a systematic review & meta-analysis of randomized controlled trials

... recent trials [8, 9] have also shown conflicting re- sults regarding timing of initiation of ...in critically ill patients with AKI undergoing RRT while in the study by Gaudry et ...in ... See full document

14

Regional citrate versus heparin anticoagulation for continuous renal replacement therapy in critically ill patients: a meta analysis with trial sequential analysis of randomized controlled trials

Regional citrate versus heparin anticoagulation for continuous renal replacement therapy in critically ill patients: a meta analysis with trial sequential analysis of randomized controlled trials

... Continuous renal replacement therapy (CRRT) has been widely used in critically ill patients with acute kidney in- jury (AKI) and anticoagulation of the ... See full document

13

Optimal timing of renal replacement therapy initiation in acute kidney injury: the elephant felt by the blindmen?

Optimal timing of renal replacement therapy initiation in acute kidney injury: the elephant felt by the blindmen?

... five randomized controlled trials (RCTs) and reported a significant survival benefit when RRT was started ...a meta-analysis of 13 observational studies and two small ...the ... See full document

7

The impact of “early” versus “late” initiation of renal replacement therapy in critical care patients with acute kidney injury: a systematic review and evidence synthesis

The impact of “early” versus “late” initiation of renal replacement therapy in critical care patients with acute kidney injury: a systematic review and evidence synthesis

... quantitative analysis, the magnitude of the mortality benefit reported in this trial associated with “early” RRT has not been reproduced by subsequent investigators, for reasons that are not ...our ... See full document

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Impact on mortality of the timing of renal replacement therapy in patients with severe acute kidney injury in septic shock: the IDEAL ICU study (initiation of dialysis early versus delayed in the intensive care unit): study protocol for a randomized contr

Impact on mortality of the timing of renal replacement therapy in patients with severe acute kidney injury in septic shock: the IDEAL ICU study (initiation of dialysis early versus delayed in the intensive care unit): study protocol for a randomized controlled trial

... with patients with AKI, with or without sepsis, suggest on the contrary that there may be a benefit to early initiation of RRT ...A meta-analysis published in 2008 by Seabra [18], which ... See full document

10

Early versus late initiation of renal replacement therapy impacts mortality in patients with acute kidney injury post cardiac surgery: a meta analysis

Early versus late initiation of renal replacement therapy impacts mortality in patients with acute kidney injury post cardiac surgery: a meta analysis

... the meta- analysis. First, the definition of early RRT criteria was different in the included studies, which may have led to the difference in the requirement for RRT and the subse- quent therapeutic ... See full document

10

Early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury (The ELAIN Trial): study protocol for a randomized controlled trial

Early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury (The ELAIN Trial): study protocol for a randomized controlled trial

... in critically ill patients used the time from randomization to commencement of continuous RRT to define ‘early’ and ‘late’ [8, ...‘lateinitiation of continuous ...the ... See full document

11

Sex differences in acute kidney injury requiring dialysis

Sex differences in acute kidney injury requiring dialysis

... ises controlled by a health care provider, during which medical care is the responsibility of one or more consul- ...of acute kidney injury requiring renal replacement ... See full document

7

Delivered dose of renal replacement therapy and mortality in critically ill patients with acute kidney injury

Delivered dose of renal replacement therapy and mortality in critically ill patients with acute kidney injury

... provide replacement fluid in variable pro- portions of pre/post-dilution, it is important to keep this in ...CRRT patients receiving more- intensive dose had significantly lower body ...larger ... See full document

14

Prevention and treatment of sepsis-induced acute kidney injury: an update

Prevention and treatment of sepsis-induced acute kidney injury: an update

... the kidney should be revised ...in patients with ...fluid therapy in septic shock ...expose patients to severe hypovolemia and recur- rent renal ... See full document

10

Long term quality of life in critically ill patients with acute kidney injury treated with renal replacement therapy: a matched cohort study

Long term quality of life in critically ill patients with acute kidney injury treated with renal replacement therapy: a matched cohort study

... AKI-RRT patients were matched to non-AKI-RRT patients based on four criteria, we cannot exclude that matched patients had a different profile compared to AKI-RRT ...for patients with better ... See full document

11

Micronutrient and amino acid losses in acute renal replacement therapy

Micronutrient and amino acid losses in acute renal replacement therapy

... body's response to the oxidative stress of critical illness, essential to the functioning of the antioxidant glutathione peroxidase. Plasma selenium levels have been demonstrated to be low in critically ill ... See full document

17

Targeted therapy in triple-negative metastatic breast cancer: a systematic review and meta-analysis

Targeted therapy in triple-negative metastatic breast cancer: a systematic review and meta-analysis

... final analysis included twelve trials comprising 2,054 patients with TNBC, which compared conventional CT alone against CT combined with targeted therapy (bevacizumab [Bev], sorafenib [Sor], ... See full document

11

Pregnancy outcomes in patients with acute kidney injury during pregnancy: a systematic review and meta analysis

Pregnancy outcomes in patients with acute kidney injury during pregnancy: a systematic review and meta analysis

... The following information was retrieved from the stud- ies included: definition of AKI, country in which the study was performed, number of patients, number of pregnancies, patient age, median/mean serum creatine ... See full document

9

Renal replacement therapy is an independent risk factor for mortality in critically ill patients with acute kidney injury

Renal replacement therapy is an independent risk factor for mortality in critically ill patients with acute kidney injury

... and renal function at hospital discharge. Descriptive, univariate analysis was performed on all parameters in order to find significant differences between different treatment groups using Student’s t-test ... See full document

9

Acute kidney injury in the ICU: from injury to recovery: reports from the 5th Paris International Conference

Acute kidney injury in the ICU: from injury to recovery: reports from the 5th Paris International Conference

... upon renal function and urine production than will have changes in ...decreased renal function, as evidenced by the development of oliguria, is one of the first visible signs of ...on renal function ... See full document

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Inclusion and definition of acute renal dysfunction in critically ill patients in randomized controlled trials: a systematic review

Inclusion and definition of acute renal dysfunction in critically ill patients in randomized controlled trials: a systematic review

... of acute renal dysfunction would be useful for clinical practice, research, and public health ...ing renal dysfunction as a secondary ...of critically ill ... See full document

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