[PDF] Top 20 Complement and systemic lupus erythematosus
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Complement and systemic lupus erythematosus
... of lupus- like autoimmunity [157,158], which provides further evidence that complement-deficient mice are a useful model to study the association between complement deficiency and SLE, first ... See full document
15
Anti C1q autoantibodies amplify pathogenic complement activation in systemic lupus erythematosus
... The complement system is a central com- ponent of innate immunity that exhibits three pathways of activation: classical, alter- native, and ...as systemic lupus erythematosus (SLE) and ... See full document
5
Major histocompatibility complex haplotypes and complement C4 alleles in systemic lupus erythematosus Results of a multicenter study
... In a multicenter study more than 300 central European systemic lupus erythematosus (SLE) patients were examined for HLA-B, HLA-DR, and complement C4 phenotypes. For 174 SLE patients MHC ... See full document
7
Immunofluorescent localization of immunoglobulins, complement, and fibrinogen in human diseases I Systemic lupus erythematosus
... Summary Immunofluorescence studies on tissues of patients with systemic lupus erythematosus SLE revealed Y2- and VylM-immunoglobulins, complement, and fibrinogen localized in renal glome[r] ... See full document
9
Defect of a complement receptor 3 epitope in a patient with systemic lupus erythematosus
... predominantly cutaneous manifestations of a systemic lupus erythematosus with an immune vasculitis and panniculitis. The deficiency of the CR3 epitope was demonstrated using flow cytometry. The ... See full document
8
Mutations in genes encoding complement inhibitors CD46 and CFHaffect the age at nephritis onset in patients with systemic lupus erythematosus
... of complement caused by inherited or acquired deficiencies of complement inhibitors could thus be involved in development and exacerbations of SLE ...in complement inhibitors have already been ... See full document
9
Impact of C4, C4A and C4B gene copy number variation in the susceptibility, phenotype and progression of systemic lupus erythematosus
... volunteers answered a questionnaire, emphasizing signs and symptoms of autoimmune diseases and recurrent infections, which could be related to deficiency of some component of Complement. In this study, recurrent ... See full document
8
Multiallelic copy number variation in the complement component 4A (C4A) gene is associated with late-stage age-related macular degeneration (AMD)
... Here, we performed a genetic association study of com- plement C4CNVs in 1536 AMD cases and 1109 un- affected controls from three independent studies [32]. This identified a strong protective association with an increase ... See full document
9
Inherited incomplete deficiency of the fourth component of complement (C4) determined by a gene not linked to human histocompatibility leukocyte antigens
... had systemic lupus erythematosus and selective incomplete deficiency of the fourth component of complement (C4) (2-5% of the normal ... See full document
7
The lupus band test in systemic lupus erythematosus patients
... and complement compo- nents in the skin of patients with LE, demonstrable as a linear band at the basement membrane zone, was then named the lupus band test ...various complement components have been ... See full document
6
Successful use of Ustekinumab in a Patient with Psoriasis, Psoriatic Arthritis and Systemic Lupus Erythematosus: A Case report and Review of literature
... positive lupus anticoagulant, AIHA that responded to rituximab and ...induced lupus was low because AIHA preceded any biological agent administration and thrombocytopenia preceded infliximab ... See full document
5
GAMMA GLOBULIN AND COMPLEMENT IN THE DISEASED KIDNEY
... with systemic lupus erythematosus Patient 6, first treated with rabbit antihuman complement previously absorbed with human -y-globulin, and then stained with fluorescein-conjugated sheep[r] ... See full document
8
Lupus Band Test in Systemic Lupus Erythematosus
... Although the number of patients with renal disease is small in our study cohort, all those biopsied show a proliferative histology. Seven of these 9 had a positive LBT in the NLSE skin. Seven of them had low ... See full document
11
Population and family studies of three disease related polymorphic genes in systemic lupus erythematosus
... C4A2 complement component, Humhv3005 and the T cell antigen receptor alpha chain gene) are investigated in 81 individuals from 14 multiplex SLE families, 41 unrelated lupus patients, and 88 unrelated ... See full document
8
Studies of immune functions of patients with systemic lupus erythematosus T cell subsets and antibodies to T cell subsets
... active systemic lupus erythematosus (SLE) plus complement are able to eliminate concanavalin A-induced suppressor function for the proliferative responses of T cells to allogeneic lymphocytes ... See full document
11
Secondary angle closure glaucoma by lupus choroidopathy as an initial presentation of systemic lupus erythematosus: a case report
... a systemic hyperosmolar state from pro- teinuria and hypoalbuminemia associated with nephrotic syndrome contributes to the leakage of fluid into the suprachoroidal space ... See full document
7
Ocular Manifestations of Systemic Lupus Erythematosus and Systemic Lupus Erythematosus with Antiphospholipid Syndrome.
... Ophthalmic side effects and disease can also result from the medications used to treat SLE. Both topical and systemic corticosteroids may accelerate cataract formation and may cause steroid-induced glaucoma. ... See full document
93
A study of ocular manifestations of systemic lupus erythematosus
... The hallmark finding in lupus retinopathy is cotton wool spots. They represent areas of microvascular occlusion. They may be isolated or surrounded by haemorrage. They are due to occlusion of precapillary ... See full document
109
SYSTEMIC LUPUS ERYTHEMATOSUS AND SYNDROMES POSSIBLY RELATED
... SYSTEMIC LUPUS ERYTHEMATOSUS AND SYNDROMES.. POSSIBLY RELATED![r] ... See full document
17
DNA damage levels in systemic lupus erythematosus patients with low disease activity: An evaluation by comet assay
... Oxidative stress has been implicated in the inflam- matory process of Systemic Lupus Erythematosus (SLE), particularly by the formation of anti-DNA autoantibodies, which can lead to DNA damage. The ... See full document
6
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