[PDF] Top 20 The control of foxN2/3 expression in sea urchin embryos and its function in the skeletogenic gene regulatory network

... of foxN2/3 expression in micromeres The dynamic expression pattern of FoxN2/3 is similar to the subcircuit of Blimp1, Wnt8 and Otx, as well as to their downstream genes including ... See full document

... the sea urchin, entry of -catenin into the nuclei of the vegetal cells at 4th and 5th cleavages is necessary for activation of the endomesoderm gene regulatory ...the expression of an ... See full document

... to gene regulation. The formation of the calcified endoskeleton of the sea urchin embryo is a valuable experimental system for developing such an integrated view of the genomic regulatory ... See full document

... the expression of lhx2/9 ...the regulatory state of domain 2. We note that Foxq2 morphant embryos are shorter overall along the AP axis, consistent with a crucial role of this factor in establishing ... See full document

... in expression of digestive enzymes observed in our transcriptomic analysis, provide a strong support to Xlox key role in the development of a functional ...detailed expression dynamics analyzed in this work ... See full document

... the regulatory subcircuit that mediates epithelial-to-mesenchymal transition of the SM lineage at 22-24 hpf as well as for driving late regulators of terminal differentiation (foxB and deadringer) as well as the ... See full document

... the sea urchin embryo, six3 and foxq2 are the first ANE regulatory genes expressed in the presumptive ectoderm and both transcription factors act as cardinal regulators of ANE territory specification ... See full document

... increased expression in vitro transcribed mRNA may be introduced into the egg or ...of sea urchins, or electroporated like in Ciona or chickens. In sea urchins the injected mRNA distributes ... See full document

... (End-mes Network QPCR Data), ...for expression of the genes named beneath the ...normal function of the input (activation or repression), as deduced from changes in transcript levels due to the ... See full document

... many embryos gastrulated and appeared relatively normal with respect to major structures; some were noticeably smaller, with fewer nuclei ...SoxC expression was not detectably affected ...The embryos ... See full document

... euechinoid sea urchins (subclass Euechinoidea), a group that includes most modern sea urchins, several regulatory and signaling proteins that are expressed in the micromere-PMC lineage during early ... See full document

... perturb embryos at the molecular level, or to introduce various molecular reagents into eggs or individual cells (Cheers and Ettensohn, ...protein function. The expression of dominant-negative ... See full document

... PMC(–) embryos as early as 2-3 hpd, similar to the time when we first began to detect alx1 transcripts, suggesting that both alx1 and tbr were activated quite early, and nearly simultaneously, during ... See full document

... in sea urchin development involve ectopic deployment of the skeletogenic GRN in non-micromere-derived ...of sea urchin development is that every blastomere of the early embryo can ... See full document

... box gene, and two of these genes, for which cis-regulatory evidence has also been obtained, are directly similar to the pmar1 transcripts that we functionally characterized earlier (Oliveri, Davidson, and ... See full document

... the expression of LvEts1 protein outside the large micromere territory at this stage is a consequence of the translation of ubiquitous maternal transcripts or reflects transient widespread zygotic transcription of ... See full document

... Lvalx1 function was required for activation of the micromere-PMC GRN in animal blastomeres ...to skeletogenic cells when treated with LiCl (Livingston and Wilt, ...stage embryos and cultured in ... See full document

... a gene can therefore reflect the evolutionary distance between two ...different gene sequences may produce different ...(e) gene paralogies ...and gene duplications complicate the analysis of ... See full document

... p38 is active only on the oral side at late blastula To measure the activation of p38, a phospho-specific antibody was employed. Phosphorylation of p38 triggers both activation of its kinase function and ... See full document

... and its benefits can be made as authorized capital of development in an effort to increase well-being and prosperity for all the ...in its entirety is directed on increasing its contribution in terms ... See full document