[PDF] Top 20 Effect of p38 Mitogen-Activated Protein Kinase on the Replication of Encephalomyocarditis Virus
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Effect of p38 Mitogen-Activated Protein Kinase on the Replication of Encephalomyocarditis Virus
... viral replication is affected by p38 MAPK by using its specific inhibitor, ...that p38 MAPK inhibitor clearly blocked both EMC viral protein synthesis and ...EMC virus-infected cells ... See full document
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Murine Coronavirus Replication-Induced p38 Mitogen-Activated Protein Kinase Activation Promotes Interleukin-6 Production and Virus Replication in Cultured Cells
... the virus. However, little is known about the effect of viruses, especially RNA viruses, on such altered cellular ...both p38 MAPK and JNK/SAPK pathways but not the activation of ERK1/2, a third ... See full document
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JNK and p38 Mitogen-Activated Protein Kinase Pathways Contribute to Porcine Circovirus Type 2 Infection
... viral replication can act at specific steps of the replication cycle, including entry, gene transcription, protein expression, and ...of p38 MAPK by treat- ment of HSV-1-infected cells with ... See full document
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Activation of TRAF5 and TRAF6 Signal Cascades Negatively Regulates the Latent Replication Origin of Epstein-Barr Virus through p38 Mitogen-Activated Protein Kinase
... these replication intermediates was less than that of the ...the effect of LMP1 expression on oriP activity, we cotransfected the LMP1 expression plasmid in this transient replication assay and found ... See full document
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Vitamin C inhibits NF kappa B activation by TNF via the activation of p38 mitogen activated protein kinase
... immunomodulatory effect by subtly suppressing NF- B at sites of inflammation, due to a greater availability of vitamin C to the plasma during times of acute intracellular ...HIV-1 replication in ... See full document
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Nucleoporin Phosphorylation Triggered by the Encephalomyocarditis Virus Leader Protein Is Mediated by Mitogen-Activated Protein Kinases
... on virus replication ...EMCV replication was unper- turbed when mTOR, protein kinase A (PKA), PKC, PKG, CDK, Src, Rho, Mnk, and other common kinase pathways were ...some ... See full document
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Induction of interleukin 10 is dependent on p38 mitogen activated protein kinase pathway in macrophages infected with porcine reproductive and respiratory syndrome virus
... optimal replication of some viruses [38]. In this study, viral replication was not obviously affected when cells were treated with inhibitors of p38 (SB203580), ERK1/2 (PD98059), PI3K (LY294002), and ... See full document
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p38 Mitogen-Activated Protein Kinase-Dependent Hyperinduction of Tumor Necrosis Factor Alpha Expression in Response to Avian Influenza Virus H5N1
... dose-dependent effect on the H5N1-induced TNF- ␣ ...of kinase inhibitors on the activities of p38 MAPK or ERK1/2 after H5N1 ...of p38 MAPK or ERK1/2 in macrophages infected with ... See full document
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Original Article Effect of phosphorylation of p38 mitogen-activated protein kinase on Homer1a expression in the cortex of rats with diffuse brain injury
... um activated potassium channel), influencing plasticity of synapses and protecting neurons [4, 11, ...after p38 MAPK pathway blocked by SB203580, sug- gesting that Homer1a participated in the post injury ... See full document
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Association of ERK2 mitogen-activated protein kinase with human immunodeficiency virus particles.
... their replication cycle, including transcription of the integrated pro- virus, translation of viral mRNAs, and posttranslational mod- ifications of viral ...nodeficiency virus type 1 (HIV-1) ... See full document
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Toll-Like Receptor 4-Mediated Activation of p38 Mitogen-Activated Protein Kinase Is a Determinant of Respiratory Virus Entry and Tropism
... cell-free virus via quantitative reverse transcription-PCR (RT-PCR). Virus RNA or adenovirus DNA was ex- tracted from cell-free virus aliquots using the viral RNA minikit or DNA blood and tissue ... See full document
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Epstein-Barr Virus (EBV) Tegument Protein BGLF2 Promotes EBV Reactivation through Activation of the p38 Mitogen-Activated Protein Kinase
... simian virus 5 [SV5] paramyxovirus) at their carboxyl ...and protein expression was verified by transfection followed by immunoblotting with anti-V5 antibody (AbD ...varicella-zoster virus (VZV) ... See full document
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Herpes Simplex Virus Type 1 ICP27 Induces p38 Mitogen-Activated Protein Kinase Signaling and Apoptosis in HeLa Cells
... of p38 signaling leads to apop- ...of p38 signaling in the absence of strong JNK activation results in ...of p38 and JNK ...the p38 inhibition did not completely prevent phosphorylation of ... See full document
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Activation of the Mitogen-Activated Protein Kinase p38 by Human Cytomegalovirus Infection through Two Distinct Pathways: a Novel Mechanism for Activation of p38
... Western blot analysis. Fibroblasts were grown to confluence, serum starved for 48 h, and then infected with HCMV at a multiplicity of infection (MOI) of 2 to 5 PFU per cell as described elsewhere (19). In experiments ... See full document
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Herpes Simplex Virus Type 1 Blocks the Apoptotic Host Cell Defense Mechanisms That Target Bcl-2 and Manipulates Activation of p38 Mitogen-Activated Protein Kinase To Improve Viral Replication
... Proteins, plasmids, and antibodies. Purified Jun and ATF-2 proteins were from Insight Biotechnology, Wembley, United Kingdom. Plasmid SEK-AL, cod- ing for the Ala-220 Leu-224 dominant-negative MKK4 (SKK1) mutant, was a ... See full document
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Hypertonicity regulates the function of human neutrophils by modulating chemoattractant receptor signaling and activating mitogen activated protein kinase p38
... of p38 and ERK1/2 in the signaling events leading to superoxide formation and degranulation using SB203580 and PD98059, a specific inhibitor of ...the p38 and ERK1/2 pathways reduced enzyme release by 35 ... See full document
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Epstein-Barr virus latent membrane protein 2 associates with and is a substrate for mitogen-activated protein kinase.
... signal protein interactions and activities, and the im- plication is that LMP2a phosphorylation (on serines as well as tyrosines) has functional ...this effect most likely involves the S102 ...tyrosine ... See full document
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Mitogen Activated Protein kinase signal transduction pathways in the prostate
... this effect is not necessary for apoptosis caused by this receptor suggesting other pathways are acti- vated ...this protein caused hyperactivation of NF-kappaB and impairment of JNK and p38 ... See full document
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Human Immunodeficiency Virus Type 1 Nef Induces Programmed Death 1 Expression through a p38 Mitogen-Activated Protein Kinase-Dependent Mechanism
... Recent evidence from several groups has suggested that viral persistence and chronic T-cell receptor (TCR) stimulation may contribute to virus-specific increase of PD-1 on T cells (6, 32). Accordingly, a ... See full document
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Mitogen-Activated Protein Kinase-Activated Kinase RSK2 Plays a Role in Innate Immune Responses to Influenza Virus Infection
... be activated upon influenza virus infection ...influenza virus-induced activation of RSK2 may lead to the stimulation of NF- B and subsequent in- duction of an antiviral ...reporter protein ... See full document
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