[PDF] Top 20 The effect of taurine on dystrophic muscle tissue function
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The effect of taurine on dystrophic muscle tissue function
... of muscle damage (Radley et ...evident, muscle fibrosis is far less pronounced than that of the human condition, and after this initial wave of degeneration the disease follows a far more benign ... See full document
285
Further Studies on Taurine and Spirulina Therapeutic Effects on Liver Abnormalities in Streptozotocin Induced Diabetic Rats
... Stabilizing the blood glucose level is mainly one of the fundamental roles of the liver cells. This step can be achieved by storing or breakdown of glycogen in liver cells as a response to insulin signals [1]. Diabetes ... See full document
9
Antiobesity and hypolipidemic effects of lotus leaf hot water extract with taurine supplementation in rats fed a high fat diet
... [11]. Taurine (2-ami- noethane sulfonic acid) is abundant in the tissues of most mammalians including humans[12,13] and blood taurine concentration was lowered in the obese mice ...[14]. Taurine ... See full document
5
Effect of β-alanine treatment on mitochondrial taurine level and 5-taurinomethyluridine content
... the taurine deficient ...the taurine trans- port inhibitors, b-alanine or guanidinoethanesulfonate, decrease taurine levels by nearly 50% and lead to the development of specific pathological ...of ... See full document
7
Activity and isozyme content of lactate dehydrogenase under long-term oral taurine administration to rats
... Male Wistar rats were used in the experiments. The rats were 4.5 months old and had body weight of 190-220 g at the beginning of the experiment. Ani- mal experiment was performed in accordance with European Convention ... See full document
9
Physiological roles of taurine in heart and muscle
... to taurine utilize pharmacological levels of the b -amino acid to minimize oxidative ...drug-induced taurine deficiency potentiates Adriamycin-induced oxidative stress in the heart, an effect thought ... See full document
8
A Review on the Biomedical Importance of Taurine
... 3.11 Taurine and Retinal Photoreceptor Activity The common eye disease cataract demonstrates the importance of lens ...Since taurine acts as an antioxidant directly, it prevents changes in the levels of ... See full document
7
Testing of therapies in a novel nebulin nemaline myopathy model demonstrate a lack of efficacy
... congenital muscle disorders causing skeletal muscle weakness and, in some cases, death soon after ...filament function, are responsible for approximately 50% of nemaline myopathy ...reduced ... See full document
10
The physiological effects of nutritional thiol supplementation : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Sport and Exercise Science at Massey University, Manawatu, New Zealand
... tight taurine control for its role in various physiological functions (De Luca, Pierno, & Camerino, ...greater taurine urinary excretion when taurine intake is high (Chesney et ...the ... See full document
178
Poloxomer 188 Has a Deleterious Effect on Dystrophic Skeletal Muscle Function
... fatal muscle wasting disease for which there is currently no cure and limited palliative ...DMD muscle increases the permeability of the sarcolemma, particularly during lengthening or ‘‘eccentric’’ ... See full document
9
Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis
... to dystrophic skeletal muscle ...respiratory function and grip strength ...skeletal muscle function ...skeletal muscle strength ...better effect on dystrophic ... See full document
15
Glucocorticoids counteract hypertrophic effects of myostatin inhibition in dystrophic muscle
... blocks muscle hypertrophic effects of Mstn ...rescuing dystrophic muscle from the atrophic effects of chronic Pred treat- ment, we performed a trial in ...induces muscle wasting in mdx mouse ... See full document
17
Irisin treatment improves healing of dystrophic skeletal muscle
... adipose tissue, such as Ucp-1, Cidea, Cpt1b and Dio2 [9]. The effect of Irisin in mouse models is distinct and well ...skeletal muscle and is cleaved to give rise to detectable levels of Irisin in ... See full document
14
A GDF11/myostatin inhibitor, GDF11 propeptide-Fc, increases skeletal muscle mass and improves muscle strength in dystrophic mdx mice
... etal muscle homeostasis [47, ...skeletal muscle may be used to achieve high levels of protein expression in the target tissue for local effect, although a considerable frac- tion of the vector ... See full document
16
<p>Effect of bupivacaine and adjuvant drugs on skeletal muscle tissue oximetry and blood flow: an experimental study</p>
... skeletal muscle blood fl ow has not been adequately addressed yet. Skeletal muscle vasculature is rich in α 1 and α 2 adrenoreceptors that both mediate a profound vasoconstrictive response and resulting ... See full document
10
A role for taurine in mitochondrial function
... that taurine is found in very high concentrations in oxidative tissue, but in lower concentrations in glycolytic ...porcine muscle tissue determined that taurine is found in high ... See full document
8
Rapamycin Ameliorates Dystrophic Phenotype in mdx Mouse Skeletal Muscle
... general effect of RAPA on muscle pathology in mdx mice, we compared local versus systemic ad- ministration of RAPA on both disease pathology and mTOR ...and muscle fiber necro- sis when RAPA was ... See full document
8
AAV CRISPR editing rescues cardiac and muscle function for 18 months in dystrophic mice
... skeletal muscle and cardiac transduc- tion in mdx mice (13, ...skeletal muscle, limited dystrophin restoration in the heart, and no improvement in cardiac histology and hemodynamic ...skeletal ... See full document
14
Effect of renal function on the pharmacokinetics of fimasartan: a single-dose, open-label, Phase I study
... Fimasartan was rapidly absorbed after a single oral dose of 120 mg, with similar concentration-time profiles between the two groups (Figure 1). The t max and t 1/2 were comparable in both groups. The mean values for C ... See full document
9
Characterisation and strategic treatment of dystrophic muscle
... skeletal muscle necrosis phase represented by the 3-week-old mice, mdx have greatly reduced body weights compared to ...skeletal muscle necrosis causing ill ... See full document
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