[PDF] Top 20 Epithelial P2X purinergic receptor channel expression and function
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Epithelial P2X purinergic receptor channel expression and function
... CF epithelial cell lines and primary cultures derived from the lung, airways, and other ...airway epithelial cell lines and primary ...protein expression at the epithelial plasma ... See full document
11
Ocular transient receptor potential channel function in health and disease
... TRPV1 expression in HCEC has potential clinical rele- vance since in TRPV1 knockout mice re-epithelialization and restoration of tissue transparency following debride- ment was delayed in these mice compared to ... See full document
12
The P2X receptor mediated regulation of inhibitory synaptic transmission
... the function of many intracellular and membrane ...of P2X receptors is their capacity to interact with other receptors involved in ...ATP receptor- mediated currents in neurons have on each ...of ... See full document
164
Molecular and cellular mechanisms of nociception in equine laminitis: purinergic P2X receptors expression and distribution
... P2X receptor expression and function in peripheral nerve has been extensively studied in other species (for review see Dunn et ...P2X3 receptor subtype immunoreactivity has been ... See full document
196
Purinergic signalling: Sensitisation of recombinant P2X receptors
... expressed receptor proteins have been reported to differ from those seen in vivo (Duller and White, ...for receptor expression, since it has very few endogenous channels, no known P I, P2, P3 or P4 ... See full document
281
Hypoxia attenuates purinergic P2X receptor-induced inflammatory gene expression in brainstem microglia
... P2X4 receptor-specific effects in cells such as microglia, where both receptor subtypes are highly expressed and are probably playing opposing ...P2X7 receptor activities, have effects at P2X1 ... See full document
11
The role of the purinergic P2X7 receptor in inflammation
... the expression and activation of the Bcl-2 family of pro- teins and the components of the caspase pathways, which dictate the lifespan and mode of cell death in such cells ...that P2X 7 R acti- vation may ... See full document
14
Implications of purinergic receptor-mediated intracellular calcium transients in neural differentiation
... cells, P2X receptors produce calcium spikes which also include activation of voltage-operating calcium ...and P2X receptors induce calcium transients that activate transcription factors responsible for the ... See full document
9
Genomic Organization of Purinergic P2X Receptors
... Purinergic P2X receptors are a family of ligand-gated cationic channels activated by extracellular ...ATP. P2X subunit protein sequences are highly conserved between vertebrate ...in P2X ... See full document
22
Probing the Roles of Receptor Structure, Drug Receptor Interactions, and Receptor Crosstalk in Ligand Gated Ion Channel Function
... ion channel subtypes are modulated by each other when they are activated simultaneously by their own neurotransmitters (4– 10, 12–17, ...heterologous expression systems, the interaction is not a ... See full document
220
Expression of P2 Purinergic Receptors in Mesenchymal Stem Cells and their Roles in Extracellular Nucleotide Regulation of Cell Functions.
... paracrine purinergic signalling via activation of the P2 receptors on the cell surface, which represents one of the most common signalling ...P2 receptor-mediated purinergic signalling plays an ... See full document
37
Ion channel diversity, channel expression and function in the choroid plexuses
... outward-rectifying channel, which is activated by increases in cell ...transient receptor potential channels (TRPV4 and TRPM3) and purinoceptor type 2 (P2X) receptor operated ... See full document
16
Expression of transient receptor potential channel 6 in cervical cancer
... determine expression of ...TRPC6 expression did not significantly correlate with clinicopathologic factors, including age, FIGO stage, and lymph node metastatic status (P ...TRPC6 expression was ... See full document
6
Purines as potential morphogens during embryonic development
... of purinergic signalling are expressed in the early embryo raising the possibility that ATP, ADP and adenosine may contribute to the mechanisms of embryonic ...where purinergic signalling is indeed ... See full document
19
P2X-Selective Purinergic Antagonists Are Strong Inhibitors of HIV-1 Fusion during both Cell-to-Cell and Cell-Free Infection
... GFP expression (30), but was insensitive to the reverse transcriptase inhibitor azidothymi- dine (AZT) (not ...the purinergic signaling acts at or prior to the induction of viral membrane fusion ... See full document
12
Potential role of LINC00996 in colorectal cancer: a study based on data mining and bioinformatics
... offer significant amounts of raw data. Our results indicated that LINC00996 is significantly decreased in CRC tissues compared with non-tumor tissues. In addition, we found that low level of LINC00996 is associated with ... See full document
11
Lack of a functioning P2X7 receptor leads to increased susceptibility to toxoplasmic ileitis
... higher scores in the amounts of swelling, angiogenesis and pus present, as well as consistency of the intestinal contents, which were much more liquefied than the intestinal contents of the C57BL/6J mice. Blood was only ... See full document
17
Function of the Epithelial Channel Cells of the Body Wall of a Terrestrial Slug, Ariolimax Columbianus
... A Sodium concentration as a function of flow rate of fluid released by the body wall of intact slugs during 5-min stimulation of the body surface mantle and back of foot.. Flow rates are[r] ... See full document
14
Expression and prognostic significance of the polymeric immunoglobulin receptor in epithelial ovarian cancer
... IL-8 receptor-blocking or neutralisation of soluble IL-8 ...PIGR expression and the described association might therefore not be applic- able for the present ... See full document
8
Expression and function of the insulin receptor substrate proteins in cancer
... IRS expression, there is also evi- dence that the expression of IRS-1 could correlate negatively with tumor ...but expression decreases in more poorly differentiated, higher-grade tumors ...IRS-1 ... See full document
15
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