[PDF] Top 20 The Lytic Cycle of Epstein-Barr Virus Is Associated with Decreased Expression of Cell Surface Major Histocompatibility Complex Class I and Class II Molecules
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The Lytic Cycle of Epstein-Barr Virus Is Associated with Decreased Expression of Cell Surface Major Histocompatibility Complex Class I and Class II Molecules
... MHC class I molecules, BZLF1 ⫹ cells expressed reduced levels of surface MHC class II molecules, ranging from 40 to 50% of levels in latent ...(CD54) expression was ... See full document
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Distinct Roles of Extracellular Domains in the Epstein Barr Virus Encoded BILF1 Receptor for Signaling and Major Histocompatibility Complex Class I Downregulation
... class I downregulation function of the mutants displayed in ...MHC class I downregulation is shown in ...the cell surface level of MHC class I relative to cells ... See full document
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The Missing Link in Epstein-Barr Virus Immune Evasion: the BDLF3 Gene Induces Ubiquitination and Downregulation of Major Histocompatibility Complex Class I (MHC-I) and MHC-II
... MHC molecules at, and their internaliza- tion from, the cell surface involves ubiquitination of MHC mole- cules and a proteasome-dependent ...MHC molecules for ubiquitination has been ... See full document
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Cell Surface Major Histocompatibility Complex Class II Proteins Are Regulated by the Products of the γ134.5 and UL41 Genes of Herpes Simplex Virus 1
... of cell-mediated immune responses appears to be critical for viral pathogens which establish latent ...MHC class I-mediated immune ...MHC class II-medi- ated T-cell responses ... See full document
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Herpesvirus Interference with Major Histocompatibility Complex Class II-Restricted T-Cell Activation
... replicative cycle have been developed for two human gammaherpesviruses (22, ...HLA class II-restricted T-cell activation, can now be explored for cells undergoing replication of these ... See full document
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The Epstein-Barr Virus-Encoded BILF1 Protein Modulates Immune Recognition of Endogenously Processed Antigen by Targeting Major Histocompatibility Complex Class I Molecules Trafficking on both the Exocytic and Endocytic Pathways
... MHC-I molecules for degradation through BILF1 ...E cycle antigens, but not of late viral ...EBV lytic cycle, but only ...BILF1 expression through the lytic cycle ... See full document
11
Downregulation of Major Histocompatibility Complex Class I Molecules by Kaposi's Sarcoma-Associated Herpesvirus K3 and K5 Proteins
... the surface expression of MHC class I molecules ...early lytic cycle of viral replication, and their gene products exhibit 40% amino acid identity ...a virus ... See full document
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Inhibition of Heavy Chain and β2-Microglobulin Synthesis as a Mechanism of Major Histocompatibility Complex Class I Downregulation during Epstein-Barr Virus Replication
... lymphoblastoid cell lines, the EBV lytic cycle and MHC class I downregulation are paralleled by downregulation of MHC class II, CD40, and CD54 while CD19, CD80, and CD86 ... See full document
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Efficient Class II Major Histocompatibility Complex Presentation of Endogenously Synthesized Hepatitis C Virus Core Protein by Epstein-Barr Virus-Transformed B-Lymphoblastoid Cell Lines to CD4+ T Cells
... high expression and/or retention of the protein in transfected ...during cell remodeling to generate an autophago- some ...the cell surface when unfixed cells are used (data not ...charged ... See full document
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Identification of Major Histocompatibility Complex Class II-Restricted Antigens and Epitopes of the Epstein-Barr Virus by a Novel Bacterial Expression Cloning Approach
... for lytic cycle antigens of ...bacterial expression vector mix, and bacteria were transformed with the ligation mix cultured in one 96-well plate at 60 ... See full document
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Analysis of Pigtail Macaque Major Histocompatibility Complex Class I Molecules Presenting Immunodominant Simian Immunodeficiency Virus Epitopes
... MHC class I alleles. Up to 96 MHC class I cDNA clones from six pigtail macaques underwent forward and reverse sequencing, generating 700- to 1,000-bp ... See full document
12
Effect of herpes simplex virus types 1 and 2 on surface expression of class I major histocompatibility complex antigens on infected cells.
... We focused on the primary CTL response in C57BL/6 H-2b mice following the local injection of infectious virus in the hind footpads, and it was demonstrated that one or more of the HSV-en[r] ... See full document
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Theiler's virus persistence and demyelination in major histocompatibility complex class II-deficient mice.
... products. Major his- tocompatibility complex (MHC) class I and II genes control the development and function of numerous cells of the im- mune ...encephalomyelitis virus ... See full document
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A Human Herpesvirus 7 Glycoprotein, U21, Diverts Major Histocompatibility Complex Class I Molecules to Lysosomes
... gp60, associated with class I molecules soon after synthesis, since this association was al- ready apparent after a 10-min pulse-label period ...The class I-associated ... See full document
12
Human Cytomegalovirus-Encoded Immune Modulators Partner To Downregulate Major Histocompatibility Complex Class I Molecules
... of class I protein could become substrates for US2-mediated degra- ...the virus more effective coverage of a broad range of class I ...infected cell susceptible to attack by NK ... See full document
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GRP78, a Coreceptor for Coxsackievirus A9, Interacts with Major Histocompatibility Complex Class I Molecules Which Mediate Virus Internalization
... and cell entry. CAV-9 is a virus genetically related to coxsackie B viruses and associated with autoimmune IDDM (22, ...MHC-I molecules in the endoplasmic reticu- lum (ER) lumen ...the ... See full document
11
Structural and Functional Dissection of Human Cytomegalovirus US3 in Binding Major Histocompatibility Complex Class I Molecules
... There are several possible mechanisms by which the luminal domain of US3 could mediate ER retention. First, although US3 does not contain any of the known linear sequences sig- naling for ER retention, it is possible ... See full document
8
Mouse Norovirus Infection Reduces the Surface Expression of Major Histocompatibility Complex Class I Proteins and Inhibits CD8+ T Cell Recognition and Activation
... replication complex (35), implying a potential impediment to protein and mem- brane trafficking in this ...MHC class I molecules are targeted for degradation via the proteasome, possibly via ... See full document
18
Cell specific and interferon inducible expression of chicken major histocompatibility class II genes
... Northern blot analysis of chicken B-actin mRNA transcription from different uninduced chicken cell lines and bursa cells with MQ-NCSU induced with 1:200 and 1:400 dilutions of ChIFN.... [r] ... See full document
112
Recovery from Friend disease in mice with reduced major histocompatibility complex class I expression.
... We investigated the effects of reduced H-2D& expression on recovery from Friend disease by using H-2b homozygous mice carrying a single P2-microglobulin gene disruption.. These mice had [r] ... See full document
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