[PDF] Top 20 The Epstein-Barr Virus BDLF4 Gene Is Required for Efficient Expression of Viral Late Lytic Genes
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The Epstein-Barr Virus BDLF4 Gene Is Required for Efficient Expression of Viral Late Lytic Genes
... of Viral Late Lytic Genes Takahiro Watanabe, Yohei Narita, Masahiro Yoshida, Yoshitaka Sato, Fumi Goshima, Hiroshi Kimura, Takayuki Murata Department of Virology, Nagoya University Graduate ... See full document
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Fatty Acid Synthase Expression Is Induced by the Epstein-Barr Virus Immediate-Early Protein BRLF1 and Is Required for Lytic Viral Gene Expression
... magnesium acetate) at 94°C for 35 min before the chip hybridization. Fifteen micrograms of fragmented cRNA was then added to a hybridization cocktail. The hybridization cocktail contains the following ingredients: 0.05 ... See full document
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Differentiation-Dependent LMP1 Expression Is Required for Efficient Lytic Epstein-Barr Virus Reactivation in Epithelial Cells
... enhances lytic EBV reactivation in EBV-infected epithelial cell ...different lytic infection-inducing agents (including differentiation stimuli, TPA, and sodium butyrate) and occurred in three different ... See full document
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Lytic Cycle Gene Regulation of Epstein-Barr Virus
... the Epstein-Barr virus (EBV) oriP sequence stably transfected into Akata Burkitt’s lymphoma cells were used to analyze EBV lytic cycle gene ...of late lytic cycle ... See full document
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Mutant Cellular AP-1 Proteins Promote Expression of a Subset of Epstein-Barr Virus Late Genes in the Absence of Lytic Viral DNA Replication
... all viral late genes are regulated by the same mechanism in different ...of viral kinetic classes assumed that temporal expression of viral genes during reactivation was ... See full document
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Epstein-Barr Virus BKRF4 Gene Product Is Required for Efficient Progeny Production
... ABSTRACT Epstein-Barr virus (EBV), a member of human gammaherpesvirus, infects mainly B ...and lytic, and is reactivated occasionally from the latent stage to the lytic ...EBV ... See full document
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Role of the Epstein-Barr Virus Rta Protein in Activation of Distinct Classes of Viral Lytic Cycle Genes
... in late gene ...of expression of a late gene, BLRF2, in Raji ...and late gene ...classify late viral genes, namely, inhibition by viral ... See full document
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Epstein-Barr Virus Small RNA (EBER) Genes: Differential Regulation during Lytic Viral Replication
... the expression of the EBERs in lytically infected cultured cells by Northern blotting could not confirm the downregulation observed in ...preceding viral latency, we measured the actual transcriptional ... See full document
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Viral Genome Methylation Differentially Affects the Ability of BZLF1 versus BRLF1 To Activate Epstein-Barr Virus Lytic Gene Expression and Viral Replication
... activate lytic protein expression is associated with differences in lytic viral gene tran- scription, we harvested RNA from 293T cells transfected with methylated or mock-methylated EBV ... See full document
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Expression of Two Related Viral Early Genes in Epstein-Barr Virus-Associated Tumors
... the expression patterns of the IR4 gene have been extensively analyzed in NPCs of North African and Chi- nese origins and in African BL biopsy specimens, and results have been compared with data from ... See full document
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Phosphoacceptor Site S173 in the Regulatory Domain of Epstein-Barr Virus ZEBRA Protein Is Required for Lytic DNA Replication but Not for Activation of Viral Early Genes
... initiate lytic viral ...activate lytic DNA replication and viral late gene ...indicated expression plasmids for wild-type or mutated ZEBRA ...of viral DNA ... See full document
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Functions of the Epstein-Barr Virus EBNA1 Protein in Viral Reactivation and Lytic Infection
... in lytic infection has not been ...the lytic cycle in epithelial cells and identified two distinct roles for ...the expression of other EBV ...Since expression of the BZLF1 gene is ... See full document
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Lytic Viral Replication as a Contributor to the Detection of Epstein-Barr Virus in Breast Cancer
... with lytic viral gene expression occurring spon- taneously only within particular type III latency cell lines and only in a small percentage of the cell ...EBV lytic replication with ... See full document
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Role of the TSG101 Gene in Epstein-Barr Virus Late Gene Transcription
... the viral promoters. Of note, TSG101 is crucial for the efficient binding of Rta to these late ...express late viral proteins, leading to a decrease in the yield of virus ... See full document
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S-Like-Phase Cyclin-Dependent Kinases Stabilize the Epstein-Barr Virus BDLF4 Protein To Temporally Control Late Gene Transcription
... controlled gene expression is necessary for the propagation of ...In Epstein-Barr virus, BcRF1 associates with five viral proteins (BDLF4, BGLF3, BFRF2, BVLF1, and ...the ... See full document
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Epstein-barr virus infected gastric adenocarcinoma expresses latent and lytic viral transcripts and has a distinct human gene expression profile
... Keeping in mind that the lymphoepithelioma-like cer- vical cancers in this study were rich in lymphoid stroma, as are many EBV-infected gastric cancers, it is remark- able that these two classes of cancer clustered ... See full document
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Different Distributions of Epstein-Barr Virus Early and Late Gene Transcripts within Viral Replication Compartments
... are late (L) genes. (A) Lytic replication-induced tet-BZLF1/B95-8 cells were cultured in the absence or presence of PAA (phosphonoacetic acid) and harvested at 48 h ...(B) Expression profiles ... See full document
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The Epstein-Barr Virus Immediate-Early Gene Product, BRLF1, Interacts with the Retinoblastoma Protein during the Viral Lytic Cycle
... activates genes important in DNA synthesis. Small DNA tumor viruses encode gene products which can functionally inactivate Rb, promoting cellular proliferation and viral DNA ...the ... See full document
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The Epstein-Barr Virus BcRF1 Gene Product Is a TBP-Like Protein with an Essential Role in Late Gene Expression
... the expression of late genes is coupled to viral genome replication is well established for all herpesviruses, but the exact mechanisms of their regulation, especially by viral ... See full document
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A Redox-Sensitive Cysteine in Zta Is Required for Epstein-Barr Virus Lytic Cycle DNA Replication
... 2005 Epstein-Barr virus (EBV) reactivation from latency is known to be sensitive to redox ...stimulates viral and cellular transcription and nucleates a replication complex at the viral ... See full document
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