[PDF] Top 20 Evaluation of Nucleic Acid Amplification Tests as Reference Tests for Chlamydia trachomatis Infections in Asymptomatic Men
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Evaluation of Nucleic Acid Amplification Tests as Reference Tests for Chlamydia trachomatis Infections in Asymptomatic Men
... The sensitivities and specificities of LCR and PCR varied substantially across centers. Culture performance also varied across centers, but independently of NAAT performance. Variations in culture performance were ... See full document
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Evaluation of Self Collected Glans and Rectal Swabs from Men Who Have Sex with Men for Detection of Chlamydia trachomatis and Neisseria gonorrhoeae by Use of Nucleic Acid Amplification Tests
... C. trachomatis and ...C. trachomatis and ...C. trachomatis or ...from asymptomatic men had a poor performance for the detection of ...of men with urethritis also found that ... See full document
6
Impact of Patient Characteristics on Performance of Nucleic Acid Amplification Tests and DNA Probe for Detection of Chlamydia trachomatis in Women with Genital Infections
... of nucleic acid amplified tests (NAAT) for Chlamydia trachomatis at the cervix and in urine was examined in 3,551 women, and the impacts of clinical findings (age, endocervical and ... See full document
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Detection of Chlamydia trachomatis andNeisseria gonorrhoeae by Enzyme Immunoassay, Culture, and Three Nucleic Acid Amplification Tests
... DNA amplification assays can be ensured by retesting initially positive specimens by a different amplifi- cation method, as was done in the present ...additional tests, a strategy known as discrepant ...the ... See full document
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Evaluation of Bias in Diagnostic Test Sensitivity and Specificity Estimates Computed by Discrepant Analysis
... of nucleic acid amplification (NAA) tests to the field of diagnostic testing has highlighted the problems presented by imperfect reference ...of Chlamydia trachomatis ... See full document
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Head to Head Multicenter Comparison of DNA Probe and Nucleic Acid Amplification Tests for Chlamydia trachomatis Infection in Women Performed with an Improved Reference Standard
... nonamplified tests were combined with culture as a reference standard ...the reference standard, particularly in settings where cold-chain transport of specimens was ...the reference stan- ... See full document
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Evaluation of the NucliSens Basic Kit for Detection ofChlamydia trachomatis and Neisseria gonorrhoeaein Genital Tract Specimens Using Nucleic Acid Sequence Based Amplification of 16S rRNA
... C. trachomatis, while NASBA for 16S rRNA was 10-fold more sensitive than either the plasmid or the omp1 assay and 10-fold more sensitive than PCR ...transcription-mediated amplification tests for C. ... See full document
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Use of Multiple Nucleic Acid Amplification Tests To Define the Infected Patient “Gold Standard” in Clinical Trials of New Diagnostic Tests for Chlamydia trachomatis Infections
... swab specimens were obtained from males for the following assays: N. gonor- rhoeae culture, Combo 2, and LCx. Swab specimens were collected before the first-catch urine specimen. Females provided four endocervical swab ... See full document
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Nucleic Acid Amplification Tests for Diagnosis of Neisseria gonorrhoeae Oropharyngeal Infections
... Study procedures. From July 2003 until December 2006, at-risk patients at three participating Birmingham, AL, clinics were approached for study enroll- ment. The participants were recruited from the Jefferson County ... See full document
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Urine Specimens from Pregnant and Nonpregnant Women Inhibitory to Amplification of Chlamydia trachomatis Nucleic Acid by PCR, Ligase Chain Reaction, and Transcription Mediated Amplification: Identification of Urinary Substances Associated with Inhibition and Removal of Inhibitory Activity
... Nucleic acid amplification (NAA) techniques such as PCR, ligase chain reaction (LCR), and transcription-mediated am- plification (TMA) have greatly improved our ability to diag- nose Chlamydia ... See full document
5
Diagnosis of Chlamydia trachomatis infections in asymptomatic men and women by PCR assay
... Nucleic acid amplification techniques such as PCR involve exponential amplification of well-defined DNA targets, result- ing in enhanced sensitivity of detection compared with the ... See full document
5
Determination of Chlamydia trachomatisPrevalence in an Asymptomatic Screening Population: Performances of the LCx and COBAS Amplicor Tests with Urine Specimens
... urogenital Chlamydia trachomatis infections run an asymptomatic course and therefore remain undetected and subsequently ...DNA amplification tech- niques (Amplicor PCR [Roche Diagnostic ... See full document
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Comparison of Methods for Detection of Chlamydia trachomatis and Neisseria gonorrhoeae Using Commercially Available Nucleic Acid Amplification Tests and a Liquid Pap Smear Medium
... this evaluation include the fact that swabs used for testing were collected in random ...site reference standards using alternate NAATs to determine sensitivity and specificity of the test under evalua- ... See full document
5
Comparison of Three Nucleic Acid Amplification Tests for Detection of Chlamydia trachomatis in Urine Specimens
... Chlamydia trachomatis is the most prevalent bacterial sexu- ally transmitted disease in developed countries ...are asymptomatic (up to 50% of men and 80% of women), the actual number of ... See full document
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Relative Accuracy of Nucleic Acid Amplification Tests and Culture in Detecting Chlamydia in Asymptomatic Men
... Collection of specimens. After informed consent was obtained, a nurse clini- cian collected each subject’s history and carried out a standardized, limited physical examination, collecting a urethral swab specimen for a ... See full document
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Nucleic Acid Amplification Tests for Diagnosis of Neisseria gonorrhoeae and Chlamydia trachomatis Rectal Infections
... gonococcal infections and over 80% of chlamydial infections diagnosed in MSM study participants that had tests performed at both genital and rectal sites had positive rectal results only and would ... See full document
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Performance of Three Nucleic Acid Amplification Tests for Detection of Chlamydia trachomatis and Neisseria gonorrhoeae by Use of Self Collected Vaginal Swabs Obtained via an Internet Based Screening Program
... positive infections from screening assays must not be overlooked in assessing the utility of outreach screening ...from men and that the performance profiles were very similar to those seen with urethral ... See full document
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Application of the COM-B model to barriers and facilitators to chlamydia testing in general practice for young people and primary care practitioners: a systematic review
... Chlamydia trachomatis (chlamydia) is the most com- monly diagnosed bacterial sexually transmitted infection (STI) in England with 202,546 diagnoses in 2016, 63% of which were among 15 to 24-year-olds ... See full document
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Vulvovaginal Swab or First Catch Urine Specimen To Detect Chlamydia trachomatis in Women in a Community Setting?
... largely asymptomatic individuals not seeking health care, testing was carried out prospectively under routine laboratory conditions, and we compared the perfor- mances of different diagnostic tests on ... See full document
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Comparison of the APTIMA CT and GC Assays with the APTIMA Combo 2 Assay, the Abbott LCx Assay, and Direct Fluorescent Antibody and Culture Assays for Detection of Chlamydia trachomatis and Neisseria gonorrhoeae
... A total of 1,304 specimens consisting of first-catch urine and urogenital swab specimens were collected from male and female patients for detection of C. trachomatis and N. gonorrhoeae. Swab specimens were tested ... See full document
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