[PDF] Top 20 Evidence for a second function of the MA sequence in the Rous sarcoma virus Gag protein.
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Evidence for a second function of the MA sequence in the Rous sarcoma virus Gag protein.
... RSV Gag with that of HIV-1 ...HIV-1 sequence which are most important in conferring membrane binding to RSV Gag could be identi- ...Src protein (the N-terminal 10 residues), which, like the ... See full document
11
Specificity of Plasma Membrane Targeting by the Rous Sarcoma Virus Gag Protein
... myristoylated Gag proteins, such as those of RSV and equine infectious anemia virus (EIAV), is less ...of Gag (29, 51). Yet both the RSV M domain and the EIAV MA protein retain the ... See full document
11
Altered Rous sarcoma virus Gag polyprotein processing and its effects on particle formation.
... polyproteins, Gag and Gag-Pol, which migrate to the plasma ...of Gag referred to as the membrane binding (M) ...of Gag polyproteins (Gag and Gag-Pol) is necessary to form ... See full document
9
Functional chimeras of the Rous sarcoma virus and human immunodeficiency virus gag proteins.
... The results indicate that the first 10 amino acids of the human immunodeficiency virus HIV Gag protein can suppress the block to budding caused by deletions in the RSV MA sequence, much [r] ... See full document
12
Repositioning Basic Residues in the M Domain of the Rous Sarcoma Virus Gag Protein
... RSV Gag protein to be particu- larly sensitive to neutralizations of basic residues in the M ...of Gag can be blocked by neutraliza- tions of just two basic ...leukemia virus and HIV-1 ... See full document
8
Genetic analysis of the major homology region of the Rous sarcoma virus Gag protein.
... one protein, the CA and NC proteins may work together and be physically associated, even though they are cleaved during virus matura- ...to function as a unit in the retroviral life cycle is ... See full document
15
The Major Site of Phosphorylation within the Rous Sarcoma Virus MA Protein Is Not Required for Replication
... HIV MA protein have suggested that such minor modifications are ...of MA molecules (1% percent) on the C-terminal tyrosine enables them to shift from being mem- brane associated to being bound to IN ... See full document
5
Characterization of Rous Sarcoma Virus Gag Particles Assembled In Vitro
... packaging sequence psi, and recent evidence suggests that the mass of RNA in par- ticles lacking a genome is similar to the mass in those contain- ing a genome ...since Gag proteins without NC can ... See full document
12
An LYPSL Late Domain in the Gag Protein Contributes to the Efficient Release and Replication of Rous Sarcoma Virus
... binding protein (Nedd4 or a related E3 ubiquitin ...RSV Gag, while Nedd4 does ...in Gag but also the upstream NC domain, and the latter in- teraction apparently is functionally important (8, 42, ... See full document
12
Analysis of Rous sarcoma virus Gag protein by mass spectrometry indicates trimming by host exopeptidase.
... For MA, as expected, all the protein generated by in vitro cleavage was present in a nonacetylated form with no evidence for ...recombinant MA presumably reflects the effect of ...other ... See full document
6
Rous Sarcoma Virus Gag Protein-Oligonucleotide Interaction Suggests a Critical Role for Protein Dimer Formation in Assembly
... packaging sequence that allows the incorporating of the virus genome into the virion (3, ...within Gag have been found to serve important functions during ...(membrane-binding) sequence is ... See full document
11
Genetic analysis of interactions between Gag proteins of Rous sarcoma virus.
... studied Gag proteins is the Gag of the Rous sarcoma virus (RSV), which has been subjected to mutational analysis to localize regions required for virion as- sembly and release (7, ... See full document
7
Mechanistic Differences between Nucleic Acid Chaperone Activities of the Gag Proteins of Rous Sarcoma Virus and Human Immunodeficiency Virus Type 1 Are Attributed to the MA Domain
... Mounting evidence suggests that the Gag polyprotein is responsible for annealing primer tRNAs to the PBS to initiate reverse transcription in retroviruses, but only HIV-1 Gag chaperone activity has ... See full document
10
Second-Site Suppressors of Rous Sarcoma Virus CA Mutations: Evidence for Interdomain Interactions
... (CA) protein, the major structural component of retroviruses, forms a shell that encases the ribonucleoprotein complex in the virion ...the protein. Structural and sequence similarities among CA ... See full document
7
Detailed Mapping of the Nuclear Export Signal in the Rous Sarcoma Virus Gag Protein
... p10 function as an LMB-sensitive NES, it should be mentioned that the spacing of hydrophobic residues in this motif is different from the spacing of leucine residues in typical NESs, like that of HIV-1 ...anemia ... See full document
10
Membrane Binding of the Rous Sarcoma Virus Gag Protein Is Cooperative and Dependent on the Spacer Peptide Assembly Domain
... retroviral Gag proteins into a lattice are ...purified Rous sarcoma virus Gag and Gag truncations, we studied the interrelation of Gag-Gag interaction and ... See full document
13
Genetic Evidence for a Connection between Rous Sarcoma Virus Gag Nuclear Trafficking and Genomic RNA Packaging
... C gag gene from ...NLS sequence was based on the bipartite NLS of Xenopus nucleoplas- min (50), although the sequence between the essential basic motifs was mutated to allow screening for positive ... See full document
8
Insertion of a Classical Nuclear Import Signal into the Matrix Domain of the Rous Sarcoma Virus Gag Protein Interferes with Virus Replication
... The Rous sarcoma virus Gag protein undergoes transient nuclear trafficking during virus ...targeting sequence within the MA ...in Gag would affect ... See full document
9
Transport and processing of the Rous sarcoma virus Gag protein in the endoplasmic reticulum.
... the MA sequence ...a Gag mutant of human immunodeficiency virus (HIV) that is targeted to the ER membrane in a manner similar to that of IAPs was found ...the MA sequence, it ... See full document
10
The membrane-binding domain of the Rous sarcoma virus Gag protein.
... wild-type Gag were either lysed immediately or chased in the presence of excess methi- onine for 1, 2, or 4 h and then ...The Gag proteins were immunoprecipitated with rabbit antiserum against RSV, sepa- ... See full document
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