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Expression of mink cell focus-forming murine leukemia virus-related transcripts in AKR mice.
... One of the cloned endogenous MCF-related MuLV DNAs isolated from the AKR/J mouse genome, designated A-12, has been shown to be virtually identical in its 3' pol and 5' env regions to leu[r] ... See full document
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Comparison of endogenous murine leukemia virus proviral organization and RNA expression in 3-methylcholanthrene-induced and spontaneous thymic lymphomas in RF and AKR mice.
... the murine genome precluded further analysis of tumor DNA for evidence of MuLV involvement in MCA lymphomagenesis 16, we examined RNA from normal thymus, primary tumors, and tumor-derive[r] ... See full document
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Mink Cell Focus-Forming Murine Leukemia Virus Infection Induces Apoptosis of Thymic Lymphocytes
... control mice (0 h values in Table ...dead cell populations between freshly isolated thy- mic lymphocytes from MCF13-inoculated mice and those from control mice (0 h ...MCF13-inoculated ... See full document
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Ikaros, a Lymphoid-Cell-Specific Transcription Factor, Contributes to the Leukemogenic Phenotype of a Mink Cell Focus-Inducing Murine Leukemia Virus
... Mink cell focus-inducing (MCF) viruses induce T-cell lymphomas in AKR/J strain ...nonacute murine leukemia viruses, transforms thymocytes, in part, by insertional ... See full document
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Multiple endogenous xenotropic and mink cell focus-forming murine leukemia virus-related transcripts are induced by polyclonal immune activators.
... MCFenv and xenoenv oligonucleotide probes consist of 16 and 30 bp of the MCF and xenotropic 5' env regions, respectively, and 3545 Downloaded from http://jvi.asm.org/ on November 10, 201[r] ... See full document
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Kinetics of expression of infectious ecotropic, xenotropic, and mink cell focus-forming murine leukemia virus after 5-iododeoxyuridine induction of cells from high- and low-leukemia mouse strains.
... 755-765 0022-538X/83/020755-11$02.00/0 Copyright C 1983, American Society for Microbiology Kinetics of Expression of Infectious Ecotropic, Xenotropic, and Mink Cell Focus-Forming Murine [r] ... See full document
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Specific hybridization probes demonstrate fewer xenotropic than mink cell focus-forming murine leukemia virus env-related sequences in DNAs from inbred laboratory mice.
... MARTIN,1 AND ROY REPASKE' Laboratory of Molecular Microbiologyl and Laboratory of Immunopathology,2 National Institute ofAllergy and Infectious Diseases, Bethesda, Maryland 20892 We have[r] ... See full document
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Potential progenitor sequences of mink cell focus-forming (MCF) murine leukemia viruses: ecotropic, xenotropic, and MCF-related viral RNAs are detected concurrently in thymus tissues of AKR mice.
... Nucleotide sequence analysis of the 3' region of cloned T-7.2 cDNA indicated that the LTR sequences of 7.2-kb mRNAs were different from the LTRs present in infectious MCF MuLV DNAs as we[r] ... See full document
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Combined infection by Moloney murine leukemia virus and a mink cell focus-forming virus recombinant induces cytopathic effects in fibroblasts or in long-term bone marrow cultures from preleukemic mice.
... 8 0022-538X/90/083701-11$02.00/0 Copyright © 1990, American Society for Microbiology Combined Infection by Moloney Murine Leukemia Virus and a Mink Cell Focus-Forming Virus Recombinant I[r] ... See full document
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Cell surface expression of the env gene polyprotein of dual-tropic mink cell focus-forming murine leukemia virus.
... However, it remains to examine dual-tropic MCF isolates derived from mouse strains other than the AKR, as well as a variety of ecotropic, xenotropic, and amphotropic MuLV from different [r] ... See full document
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Mink Cell Focus-Forming Murine Leukemia Virus Killing of Mink Cells Involves Apoptosis and Superinfection
... to AKR lymphomagenesis was observed in early studies by ...that cell death in the thymus was a requirement for leukemogenesis in the AKR mouse ...from mice inoculated with the wild-type ... See full document
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Cloning of endogenous murine leukemia virus-related sequences from chromosomal DNA of BALB/c and AKR/J mice: identification of an env progenitor of AKR-247 mink cell focus-forming proviral DNA.
... The size and internal organization of the LTRs associated with different cloned endogenous proviral DNAs were examined and compared with analogous segments present in the proviruses of k[r] ... See full document
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Free and integrated recombinant murine leukemia virus DNAs appear in preleukemic thymuses of AKR/J mice.
... Using a series of ecotropic and nonecotropic murine leukemia virus hybridization probes, we showed that the unintegrated viral genomes are structurally analogous to those of recombinant [r] ... See full document
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Normal expression of polymorphic endogenous retroviral RNA containing segments identical to mink cell focus-forming virus.
... The nucleotide sequence of the endogenous transcript differs uniformly from the sequences of infectious ecotropic virus and MCF virus throughout the 3' portion of the env gene approximat[r] ... See full document
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Ecotropic and mink cell focus-forming murine leukemia viruses integrate in mouse T, B, and non-T/non-B cell lymphoma DNA.
... 1037 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Structures of somatically acquired murine leukemia virus MuLV genomes present in the DNA of a large panel of MuLV-i[r] ... See full document
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A direct demonstration of recombination between an injected virus and endogenous viral sequences, resulting in the generation of mink cell focus-inducing viruses in AKR mice.
... Our data demonstrate that the onset of viral leukemia is accelerated in animals containing proviruses derived from an injected chimeric virus that has recombined in vivo to acquire an MC[r] ... See full document
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Mobility of endogenous ecotropic murine leukemia viral genomes within mouse chromosomal DNA and integration of a mink cell focus-forming virus-type recombinant provirus in the germ line.
... 901-908 0022-538X/82/030901-08$02.00/0 Mobility of Endogenous Ecotropic Murine Leukemia Viral Genomes Within Mouse Chromosomal DNA and Integration of a Mink Cell Focus-Forming Virus-Type[r] ... See full document
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Heteroduplex analysis of the sequence relations between the RNAs of mink cell focus-inducing and murine leukemia viruses.
... Heteroduplex Analysis of the Sequence Relations Between the RNAs of Mink Cell Focus-Inducing and Murine Leukemia Virusest Received for publication 1 May 1978 The sequence relationships b[r] ... See full document
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Characterization of proviruses cloned from mink cell focus-forming virus-infected cellular DNA.
... One cloned MuLV DNA fragment designated MCF 1 contained sequences extending 6.8 kilobases from an EcoRI restriction site in the 5' long terminal repeat LTR to an EcoRI site located in th[r] ... See full document
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Myeloproliferative virus, a cloned murine sarcoma virus with spleen focus-forming properties in adult mice.
... DISCUSSION Our data on the MPVMSV virus complex show the following: i MPVMSV consists of at least two viral species, a replication-competent helper virus and a defective transforming vir[r] ... See full document
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