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[PDF] Top 20 Expression and functional characterization of FOXM1 in non-small cell lung cancer

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Expression and functional characterization of FOXM1 in non-small cell lung cancer

Expression and functional characterization of FOXM1 in non-small cell lung cancer

... expressing FOXM1 at a higher level survived for a shorter time than those exhibiting lower FOXM1 ...high FOXM1 expression is an important independent predictor of poorer prognosis for NSCLC ... See full document

9

Long noncoding RNA MIAT promotes non-small cell lung cancer progression by sponging miR-149-5p and regulating FOXM1 expression

Long noncoding RNA MIAT promotes non-small cell lung cancer progression by sponging miR-149-5p and regulating FOXM1 expression

... the expression of cell cycle genes essential for DNA replica- tion and mitosis ...[22–24]. FOXM1 plays an important role in the control of cell proliferation and is considered as a human ... See full document

10

Centromere protein U expression promotes non-small-cell lung cancer cell proliferation through FOXM1 and predicts poor survival

Centromere protein U expression promotes non-small-cell lung cancer cell proliferation through FOXM1 and predicts poor survival

... the Cancer Genome Atlas (TCGA) data ...NSCLC cell lines significantly inhibited cell proliferation and induced G1 phase ...NSCLC cell lines through the tran- scription factor, ...promoted ... See full document

14

Elevated expression of podoplanin and its clinicopathological, prognostic, and therapeutic values in squamous non-small cell lung cancer

Elevated expression of podoplanin and its clinicopathological, prognostic, and therapeutic values in squamous non-small cell lung cancer

... per well in 100 µL of complete medium overnight before the assay. NZ-1-IT was serially diluted to achieve a final concentration of 0.001–1000 ng/mL in PBS (Thermo Fisher Scientific) containing 0.2% human serum albumin ... See full document

12

Original Article PI3K expression predicts overall survival in lung adenocarcinoma

Original Article PI3K expression predicts overall survival in lung adenocarcinoma

... in non-small cell lung cancer (NSCLC) remains contro- ...normal lung tis- sue ...PI3K/p-PI3K expression in lung cancer tissue differed significantly from ... See full document

10

Characterization of Distinct Populations of Carcinoma-Associated Fibroblasts from Non-Small Cell Lung Carcinoma Reveals a Role for ST8SIA2 in Cancer Cell Invasion.

Characterization of Distinct Populations of Carcinoma-Associated Fibroblasts from Non-Small Cell Lung Carcinoma Reveals a Role for ST8SIA2 in Cancer Cell Invasion.

... in nonsmall cell lung cancer (NSCLC) ...of cancer cell invasion is the changes in tumor stroma recognized as ...tumor cell growth, invasion, and metastases, ... See full document

13

Significance of EpCAM and TROP2 expression in non small cell lung cancer

Significance of EpCAM and TROP2 expression in non small cell lung cancer

... nuclear expression was not seen in our ...is non-specific staining regarding that cytoplasmic expression was only focally observed in the cases which show strong membranous TROP2 ...of ... See full document

8

<p>BTLA Expression in Stage I–III Non–Small-Cell Lung Cancer and Its Correlation with PD-1/PD-L1 and Clinical Outcomes</p>

<p>BTLA Expression in Stage I&ndash;III Non&ndash;Small-Cell Lung Cancer and Its Correlation with PD-1/PD-L1 and Clinical Outcomes</p>

... Lung cancer is a common and often fatal malignant tumor, particularly nonsmall- cell lung cancer (NSCLC), which accounts for 80% of lung cancers, and most are ... See full document

10

Long noncoding RNA ANRIL could be transactivated by c-Myc and promote tumor progression of non-small-cell lung cancer

Long noncoding RNA ANRIL could be transactivated by c-Myc and promote tumor progression of non-small-cell lung cancer

... Notes: (A) ChIP was used to confirm the c-Myc-binding activity. The c-Myc antibody effectively enriched the DNA sequence covering the putative binding element. Normal rabbit igg was used as a negative control and an ... See full document

8

&lt;p&gt;Decreased IFIT2 Expression In Human Non-Small-Cell Lung Cancer Tissues Is Associated With Cancer Progression And Poor Survival Of The Patients&lt;/p&gt;

<p>Decreased IFIT2 Expression In Human Non-Small-Cell Lung Cancer Tissues Is Associated With Cancer Progression And Poor Survival Of The Patients</p>

... stable cell lines with depletion of IFIT2 by using RNAi approach, and then performed cellular func- tional studies, such as CCK-8 assay, wound-healing assay and transwell assay, in these cell ...gastric ... See full document

11

Novel classes of non coding RNAs and cancer

Novel classes of non coding RNAs and cancer

... germ cell development, stem cell self- renewal, and retrotransposon ...PIWI) expression and diverse group of cancers including pancreatic [79] and gastric [80] adenocarcinomas, sarcomas [81], hepa- ... See full document

21

Long non-coding RNA DANCR promotes the progression of non-small-cell lung cancer by inhibiting p21 expression

Long non-coding RNA DANCR promotes the progression of non-small-cell lung cancer by inhibiting p21 expression

... The chromatin immunoprecipitation assay was performed in A549 cells by using a commercial kit (EMD Millipore). After cross-linking with 1% formaldehyde at 37 ° C for 10 minutes, the cells were harvested in sodium dodecyl ... See full document

12

MicroRNA-1298 is downregulated in non-small cell lung cancer and suppresses tumor progression in tumor cells

MicroRNA-1298 is downregulated in non-small cell lung cancer and suppresses tumor progression in tumor cells

... and cell lines and acted as a biomarker and therapeutic tar- get in the pathogenesis of NSCLC ...miR-1298 expression was detected to be downreg- ulated expressed in NSCLC tissues and cell lines, and ... See full document

8

An immunohistochemical study of cyclin dependent kinase 5 (CDK5) expression in non small cell lung cancer (NSCLC) and small cell lung cancer (SCLC): a possible prognostic biomarker

An immunohistochemical study of cyclin dependent kinase 5 (CDK5) expression in non small cell lung cancer (NSCLC) and small cell lung cancer (SCLC): a possible prognostic biomarker

... the expression of CDK5 in cancer tis- sues, the relationship between CDK5 and pathological parameters has been paid more and more attention ...breast cancer, upregulated expression of CDK5 was ... See full document

8

Original Article The identification of genes associated with NSCLC prognosis based on an integrated bioinformatics analysis

Original Article The identification of genes associated with NSCLC prognosis based on an integrated bioinformatics analysis

... pancreatic cancer and correlated with patients’ poor prognosis ...B1 expression in patients with resected non-small-cell lung cancer stage I-IIIA, a pre- liminary report ... See full document

8

Expression of Derlin-1 and its effect on expression of autophagy marker genes under endoplasmic reticulum stress in lung cancer cells

Expression of Derlin-1 and its effect on expression of autophagy marker genes under endoplasmic reticulum stress in lung cancer cells

... the expression of Derlin-1 in various lung cancer cells, including small lung cancer cells and non-small lung cancer ...the expression of ... See full document

5

Original Article Co-expression of delta-catenin and RhoA is significantly associated with a malignant lung cancer phenotype

Original Article Co-expression of delta-catenin and RhoA is significantly associated with a malignant lung cancer phenotype

... positive expression and RhoA over-expres- sion is consistently found in non-small cell lung cancer, but not in normal lung tissue, and that their co-expression was ... See full document

9

High CEP55 expression is associated with poor prognosis in non-small-cell lung cancer

High CEP55 expression is associated with poor prognosis in non-small-cell lung cancer

... high expression of CEP55 had a shorter OS and DFS compared with those with low expression (OS: mean of ...CEP55 expression was significantly associated with poor prognosis in NSCLC patients who are ... See full document

12

The roles of metallothioneins in carcinogenesis

The roles of metallothioneins in carcinogenesis

... ovarian cancer [22, 118], breast cancer [119, 120], small cell lung cancer [121], non-small cell lung cancer [122], renal cell carcinoma ... See full document

20

Functions and mechanisms of long noncoding RNAs in lung cancer

Functions and mechanisms of long noncoding RNAs in lung cancer

... Noncoding RNAs (ncRNAs) are a superclass of endogenous, non-protein-coding RNA transcripts, many of which have essential functions in various cellular processes. Based on their function, ncRNAs can be classified ... See full document

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