[PDF] Top 20 The expression of the Sprouty 1 protein inversely correlates with growth, proliferation, migration and invasion of ovarian cancer cells
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The expression of the Sprouty 1 protein inversely correlates with growth, proliferation, migration and invasion of ovarian cancer cells
... in ovarian cancer cells, we found that induced expression of Spry1 activates proapoptotic processes, with implica- tion of Bcl-2 protein family and caspase ...Spry1 expression ... See full document
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<p>Long noncoding RNA SNHG16 silencing inhibits the aggressiveness of gastric cancer via upregulation of microRNA-628-3p and consequent decrease of NRP1</p>
... cell proliferation, induces cell cycle arrest and promotes cell apoptosis in vitro, and decreases tumor growth in ...miR-628 expression restricts epithelial – mesenchymal transition and metastasis in ... See full document
15
PTBP3 contributes to colorectal cancer growth and metastasis via translational activation of HIF-1α
... the expression of PTBP3 in clinical CRC samples of patients and its po- tential role and molecular mechanism in regulating CRC malignant ...PTBP3 expression promoted colon cancer cell ... See full document
14
MicroRNA-9 suppresses the growth, migration, and invasion of malignant melanoma cells via targeting NRP1
... gene expression by directly binding to the 3′ untranslated region of their target mRNA, thus result- ing in mRNA degradation or translational ...and protein expression of ...cell ... See full document
11
MicroRNA-194 promotes the growth, migration, and invasion of ovarian carcinoma cells by targeting protein tyrosine phosphatase nonreceptor type 12
... cell migration and invasion by in vitro wound healing assay and transwell ...cell migration and ...cell proliferation and reduced the capacity of cell migration and ...in ovarian ... See full document
9
<p>LncRNA EMX2OS, Regulated by TCF12, Interacts with FUS to Regulate the Proliferation, Migration and Invasion of Prostate Cancer Cells Through the cGMP-PKG Signaling Pathway</p>
... EMX2OS expression was assessed in PCa tissues, paracancer tissues, PCa cells and normal prostate epithelial cells by ...monophosphate-dependent protein kinase)-mediated proliferation, ... See full document
12
Anti-cancer Activity of Novel TM4SF5-Targeting Antibodies through TM4SF5 Neutralization and Immune Cell-Mediated Cytotoxicity
... cell proliferation, migration, and invasion ...S2) cancer patients. We also found that high TM4SF5 expression in lung adenocarcinoma patients was significantly correlated with decreased ... See full document
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MicroRNA-663 facilitates the growth, migration and invasion of ovarian cancer cell by inhibiting TUSC2
... pancreatic cancer and acute myeloid leukemia (AML) ...carcinoma cells growth by means of directly target- ing cyclin-dependent kinase inhibitor 2A (CDKN2A) and sustains non-small cell lung ... See full document
9
<p>LncRNA LEF1-AS1 Promotes Ovarian Cancer Development Through Interacting with miR-1285-3p</p>
... in ovarian cancer still remains ...osteosarcoma growth and serves as a prognostic ...on ovarian cancer ...miR-1285-3p expression was downregulated in ovarian cancer ... See full document
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Original Article LncRNA PCAT-1 plays an oncogenic role in epithelial ovarian cancer by modulating cyclinD1/CDK4 expression
... Epithelial ovarian cancer is one of the most common causes of gynecological cancer ...tumor growth in various kinds of cancers, including esopha- geal cancer, breast cancer, ... See full document
9
Jumonji domain-containing protein 1A promotes cell growth and progression via transactivation of c-Myc expression and predicts a poor prognosis in cervical cancer
... domain-containing protein 1A (JMJD1A) plays a key role in the development and progression of several ...the expression of JMJD1A is increased in cervical cancer cells and tissues, and that ... See full document
12
Down-regulation of TRIB3 inhibits the progression of ovarian cancer via MEK/ERK signaling pathway
... in ovarian cancer in protein and mRNA level, which was confirmed by expression analysis studies in the Oncomine and GEPAI ...TRIB3 expression and FIGO stage of the cancer, patho- ... See full document
15
<p>EMP1 Promotes the Proliferation and Invasion of Ovarian Cancer Cells Through Activating the MAPK Pathway</p>
... myelin protein 22 kDa (PMP22) gene family, and involved in tumor cell migration, growth, and ...brane protein (TMP), B4B. 10 The EMP1 protein consists of 157 amino acids and is a ... See full document
9
Original Article CKIP-1 serves as a negative regulator and correlates with the degree of differentiation in gastric cancer
... Gastric cancer (GC) is one of the most commonly diagnosed malignancies ...interacting protein. Though previous reports have shown that CKIP-1 plays a critical role in several types of cancers, hardly ... See full document
7
Original Article Silencing of the long non-coding RNA NEAT1 suppresses ovarian cancer cell proliferation, migration and invasion
... from cells with protein lysis buffer and protease inhibitor cock- tail (Sigma, ...The protein concentration was quantified by BCA Kit ...for 1 h, incubated with primary antibodies overnight at ... See full document
10
ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis
... MMP13 expression is necessary for the induction of tumors by ETV4 in vivo, MMT-ETV4 + shCtrl and MMT-ETV4 + shMMP13 cells were injected into the inguinal flanks of immunocom- promised mice, and tumor ... See full document
18
Recent advances in understanding the role of FOXO3
... fore, in aging muscle, FOXO3 may be similarly or even less active than in younger muscle or in models of artificially or disease-induced atrophy. Overall, these results confirm the idea that a series of upstream ... See full document
8
MicroRNA-937 is overexpressed and predicts poor prognosis in patients with colon cancer
... abnormal expression of microRNAs (miRNAs) is closely linked to the initiation and development of cancers ...gene expression at the post-transcriptional level by binding to the 3 ′ -UTR of their target mRNA ... See full document
8
<p>miRNAs: A Promising Target in the Chemoresistance of Bladder Cancer</p>
... BCa cells, Bcl-2 is regulated by miR-21, miR- 192, miR-221, miR-9, miR-675, miR-29c, and Mcl-1 and is regulated by miR-192 and ...the proliferation and apoptosis of BCa cells by regulating the ... See full document
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Original Article Regulator role of HPV E7 protein on miR-21 expression in cervical carcinoma cells and its functional implication
... Total RNA was extracted from Hela cells by Trizol reagents (Invitrogen, US). Using total RNA as the template, cDNA was synthesized by re- verse transcription kit (Invitrogen, US). HPV16 E7 specific primers were ... See full document
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