[PDF] Top 20 Fgf signalling controls the dorsoventral patterning of the zebrafish embryo
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Fgf signalling controls the dorsoventral patterning of the zebrafish embryo
... that Fgf signalling does also affect the DV axis of the early zebrafish ...of Fgf signalling does not cause the loss of mesoderm but a dorsal expansion of ventral mesodermal fates ... See full document
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A β1,4 galactosyltransferase is required for Bmp2 dependent patterning of the dorsoventral axis during zebrafish embryogenesis
... of zebrafish has allowed us to screen the knockdown phenotype of individual transferases to identify those that are essential during ...for dorsoventral patterning of the early embryo, but ... See full document
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Dorsoventral patterning of the Xenopus eye: a collaboration of Retinoid, Hedgehog and FGF receptor signaling
... DV patterning of the retina is less clear (Perron et ...and FGF signaling pathways may also play a role in the ventralization of the ...in zebrafish embryos (Hyatt et ...to FGF signaling, ... See full document
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Vegetally localised Vrtn functions as a novel repressor to modulate bmp2b transcription during dorsoventral patterning in zebrafish
... in zebrafish embryos for preparation of Vrtn-containing nuclear lysates, and five bmp2b probes ( p1-p5) located within and outside the ChIP-enriched region were labelled with biotin ... See full document
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FGF receptor signalling controls neural cell diversity in the zebrafish hindbrain by regulating olig2 and sox9
... the zebrafish hindbrain indeed give rise to SMNs of the abducens nuclei and ...that FGF-receptor signalling in hindbrain progenitors controls olig2 expression and consequently the generation ... See full document
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Anteroposterior and dorsoventral patterning are coordinated by an identical patterning clock
... that FGF signaling through MAPK phosphorylates the linker of P-Smad1/5 in ventral vegetal regions of the embryo, inhibiting P-Smad1/5 ...Thus, FGF/MAPK signaling in part controls the temporal ... See full document
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FGF signalling controls formation of the apical sensory organ in the cnidarian Nematostella vectensis
... identify signalling molecules that are involved in the embryonic patterning of Nematostella, we identified and isolated the complete set of 15 homologous transcripts of Fibroblast growth factors (FGFs) and ... See full document
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Re epithelialization of cutaneous wounds in adult zebrafish combines mechanisms of wound closure in embryonic and adult mammals
... the FGF receptor FGFR2IIIb in keratinocytes compromises wound closure in adult mouse models (Werner et ...Tg(hsp70l:dnfgfr1-EGFP) zebrafish, which upon heat- shock application express a C-terminally ... See full document
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Anteroposterior patterning of the zebrafish ear through Fgf- and Hh-dependent regulation of hmx3a expression
... of fgf genes following mis-expression of fgf3 or inhibition of Hh ...of fgf genes in Tg(hsp70:fgf3) embryos following a 30-minute heat shock (HS) at the 10-somite stage (14 ...hpf). Controls ... See full document
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Shroom3 is required downstream of FGF signalling to mediate proneuromast assembly in zebrafish
... Although the overall morphology of the embryos was indistinguishable from injected controls (Fig. 3C), knockdown of Shroom3 function significantly modified the internal organization of migrating pLLP. The ... See full document
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Zebrafish endoderm formation is regulated by combinatorial Nodal, FGF and BMP signalling
... the FGF and BMP signalling pathways have been shown to play crucial roles in formation and patterning of mesoderm and endoderm in ...Basic FGF was first identified as a mesoderm-inducing ... See full document
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Insulin like growth factor (IGF) signalling is required for early dorso anterior development of the zebrafish embryo
... (IGF) signalling pathway has been highly conserved in animal evolution and, in mammals and Xenopus, plays a key role in embryonic growth and development, with the IGF-1 receptor (IGF-1R) being a crucial regulator ... See full document
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The role of the Eph ephrin signalling system in the regulation of developmental patterning
... that they represent the earliest evolutionary split from RTK, occur- ring prior to the appearance of vertebrates. The Eph and ephrin proteins have diversified extensively during evolution of the verte- brate body plan. ... See full document
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Retinoic acid orchestrates fibroblast growth factor signalling to drive embryonic stem cell differentiation
... mouse embryo, the earliest reported retinoid activity is sporadic detection of RARE-driven b-galactosidase activity in ...mouse embryo at ...of Fgf and retinoid signalling centres persists as ... See full document
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Differentiation of cerebellar cell identities in absence of Fgf signalling in zebrafish Otx morphants
... Fig. 1. Absence of mesencephalon in OtxH embryos. (A) Western blot analysis on wild-type or OtxH zebrafish embryo extracts from end of gastrulation stage (upper panel: bud stage) or late somitogenesis stage (lower ... See full document
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Essential roles of a zebrafish prdm1/blimp1 homolog in embryo patterning and organogenesis
... these patterning defects, we analysed expression of the organizer genes boz and gsc and of the dorsoventral patterning genes chd, szl and bmp4 in prdm1 RNA-injected ... See full document
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Delta Notch signalling controls commitment to a secretory fate in the zebrafish intestine
... To generate our monoclonal antibodies, we used a ‘shotgun’ approach, based on immunization of mice with homogenates of zebrafish gut. The relatively large evolutionary divergence (450 million years) between ... See full document
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Hedgehog signaling controls dorsoventral patterning, blastema cell proliferation and cartilage induction during axolotl tail regeneration
... DV patterning information in the regenerate comes from the mature spinal ...cord controls DV progenitor cell identity during tail ...DV patterning of the neural tube is imposed from structures ... See full document
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Cell migration that orients the dorsoventral axis is coordinated with anteroposterior patterning mediated by Hedgehog signaling in the early spider embryo
... During spider development, the formation and migration of the CM cells is preceded by the formation of a single embryonic axis termed the embryonic-abembryonic (Em-Ab) axis (Fig. 1A). Centrifugal migration of the CM ... See full document
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Fgf8 controls regional identity in the developing thalamus
... station in the ventroposterior (VP) nucleus complex, known as the barreloid of the thalamus (Erzurumlu and Kind, 2001). The Fgf8 construct was co-electroporated at E10.5 with Cre (encoding Cre recombinase) into embryos ... See full document
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