[PDF] Top 20 Formulation and Evaluation of Calcium Dobesilate Microspheres using Various Polymers

... of calcium dobesilate. Calcium dobesilate (DoxiumTM)is a veno-tonic drug, which is widely prescribed in more than 60 ...attack. calcium dobesilat did not occur very frequently and had ... See full document

... Microspheres were prepared by ionotropic gelation method which involved reaction between sodium alginate and polycationic ions like calcium to produce a hydrogel network of calcium alginate. Sodium ... See full document

... HCl using various polymers such as HMC K4M, HPMC K15M, HPMC K100M, polyethylene oxide (PEO) 303 WSR and PEO N60 and its comparative study was also ... See full document

... Total six batches (F1-F6) were prepared using different polymers. All these ratios were compatible with drug and show good results in increasing solubility and dissolution profile of Glibenclamide drug. F2 ... See full document

... In this technique, initially the polymer is dissolved in a suitable solvent followed by drug addition yields its aqueous solution, Phase separation is then accomplished by changing the solution conditions by using ... See full document

... in formulation and development of novel drug delivery systems. Microspheres form an important part of such novel drug delivery ...prepared using various polymers. [4-8] ... See full document

... mucoadhesive microspheres were prepared using polymers sodium alginate, chitosan, sodium CMC by ionotropic gelation ...by using different concentrations of polymers and mucoadhesive ... See full document

... synthetic polymers of biodegradable nature. Microspheres are particles between ...are various approaches in delivering a therapeutic substance to the target site in a sustained controlled release ... See full document

... Microspheres are submicron size polymeric drug carrier systems in which the therapeutic agents are loaded inside the polymeric matrix or encapsulated or physically absorbed or chemically coupled on to the ...of ... See full document

... biodegradable polymers in sustained drug ...[2] Formulation scientists have engineered several mucoadhesive polymers for their usefulness in enhancement of bioavailability, controlled and targeted ... See full document

... the microspheres were collected by filtration by Whatman filter ...The microspheres were washed repeatedly with petroleum ether (40 - 60 °C) until free from ...The microspheres were collected and ... See full document

... are various approaches in delivering a therapeutic substance to the target site in a sustained controlled release ...is using microspheres as carries of drugs. [17] Microspheres are ... See full document

... the various Ritonavir mucoadhesive microspheres formulations were mentioned in ...mucoadhesive polymers were individually passed through sieve ≠ ...mucoadhesive polymers were dissolved in ... See full document

... the microspheres was influenced by the cross-linking agents and with the modified (SA) of different retarding ...polymers. Formulation F6 containing was found to give a maximum entrapment efficiency ... See full document

... the formulation and characterization of mucoadhesive sustained release microsphere of antihyperlipidemic drug simvastatin that would adhere in mucosa and release continuously to provide long term ...was ... See full document

... Alginate microspheres containing Eletriptan hydrobromide were prepared by emulsification ionic gelation ...of calcium Chloride solution (5% w/v) was added slowly while stirring for ionic gelation ... See full document

... Floating microspheres of Levofloxacin were prepared by solvent evaporation ...in various combinations of polymers ...prepared microspheres are subjected to evaluation for particle size, ... See full document

... by using sodium alginate as a gel forming polymer and by using natural bioadhesive polymers ...of calcium chloride ...with various concentrations of mucoadhesive ...into calcium ... See full document

... prepared using assorted polymers 4 ...these microspheres is limited owing to their short residence time at the site of ...to microspheres and developing bioadhesive ...Bioadhesive ... See full document

... Eudragit microspheres containing Atorvastatin calcium to achieve a prolonged release and specific site targeting drug delivery system profile suitable for oral ...The microspheres were prepared by a ... See full document