[PDF] Top 20 A Function Essential to Viral Entry Underlies the Hepatitis B Virus “a” Determinant
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A Function Essential to Viral Entry Underlies the Hepatitis B Virus “a” Determinant
... residues essential for infectivity could eventually mediate attachment to negatively charged molecules such as glycosami- noglycans ...of viral particles for their content in HBV envelope proteins prior to ... See full document
8
Duck Hepatitis B Virus Requires Cholesterol for Endosomal Escape during Virus Entry
... is essential for the membrane-membrane/pro- tein interaction required for release of DHBV from endo- ...C) Viral particles were treated as indicated, PEG precipitated, and used for infection of ...of ... See full document
11
Multiple Functions of Cellular FLIP Are Essential for Replication of Hepatitis B Virus
... in viral liver pathogenesis (2) and especially in HBV replication (3, ...its function and identifying the host binding partners which are necessary for HBx function are important for preventing ... See full document
19
A substitution in the pre S1 promoter region is associated with the viral regulation of hepatitis B virus
... Recently, sodium taurocholate co-transporting poly- peptide (NTCP) has been identified as a host receptor of HBV. NTCP is a bile salt transporter that is expressed on the surface of hepatocytes; it binds to the ... See full document
11
Identification of an Essential Molecular Contact Point on the Duck Hepatitis B Virus Reverse Transcriptase
... the viral DNA (42, 44). The spacer domain has no known function other than to link the terminal protein domain to the rest of ...immunodeficiency virus reverse transcriptase (1, ... See full document
7
The Hepatitis B Virus X Protein Transactivates Viral Core Gene Expression In Vivo
... The function of the HBV X-gene product during the viral life cycle is ...cloned viral DNA into hepatoma cells (2, 14, 26), raising the question whether the X gene encodes an essential ... See full document
7
Molecular analysis of hepatitis B virus "a" determinant in asymptomatic and symptomatic Mexican carriers
... hepatic function tests and HBV viral load showed that in our symptomatic patients there was hepatic damage and high viral replication, which suggests that the antivi- ral treatment with LMV was not ... See full document
7
A Conserved Gly436-Trp-Leu-Ala-Gly-Leu-Phe-Tyr Motif in Hepatitis C Virus Glycoprotein E2 Is a Determinant of CD81 Binding and Viral Entry
... encephalitis virus Neudoerfl [U27495] and dengue virus type 2 [P12823]) are shown and compared to the region encompassing the G 436 WLAGLFY sequence (underlined) in HCV ... See full document
10
Cellular Receptor Traffic Is Essential for Productive Duck Hepatitis B Virus Infection
... duck hepatitis B virus (DHBV) entry into susceptible primary duck hepatocytes (PDHs), using mutants of carboxypeptidase D (gp180), a transmembrane protein shown to act as the primary cellular ... See full document
7
Analysis of the Cytosolic Domains of the Hepatitis B Virus Envelope Proteins for Their Function in Viral Particle Assembly and Infectivity
... (pT7HB2.7) coding for the three envelope proteins (SML plas- mid). They were designed such that Cys-48, Cys-65, and Cys- 69, previously shown to be essential to SVP secretion, were not affected (30). Mutant ... See full document
11
Original Article Efficacy of sitagliptin on liver function in patients with diabetes and chronic viral hepatitis B
... A recent article on the use of exenatide or lira- glutide to improve liver lipopexia in patients has been published. The main finding of this study was that the administration of exenatide or lira- glutide in patients ... See full document
8
Hepatitis B Virus Nucleocapsid but Not Free Core Antigen Controls Viral Clearance in Mice
... detects viral infection through cel- lular ...identified viral PAMPs are nucleic acids, we have shown that without HBcAg, the intra- cellular viral RNA alone did not result in the viral ... See full document
8
APOBEC3-Independent Interferon-Induced Viral Clearance in Hepatitis B Virus Transgenic Mice
... Acute hepatitis B virus (HBV) infection is rapidly cleared in most immunocompetent adults through a combination of cy- totoxic and cytokine-mediated noncytolytic responses (6, ...are essential ... See full document
6
Interaction of Hepatitis C Virus-Like Particles and Cells: a Model System for Studying Viral Binding and Entry
... In the present study, we showed that HCV-LPs bind to various cell lines regardless of their CD81 expression. On CD81-positive cells (HuH7, NKNT-3, and Molt-4), blocking of cellular CD81 with anti-CD81 MAb did not inhibit ... See full document
10
Leptomycin B Inhibits Equine Infectious Anemia Virus Rev and Feline Immunodeficiency Virus Rev Function but Not the Function of the Hepatitis B Virus Posttranscriptional Regulatory Element
... monkey virus (MPMV) and simian retrovirus types 1 and 2 contain cis-acting RNA export elements termed constitutive transport elements (CTEs) that induce nuclear export of viral unspliced mRNA (2, 5, 36, ... See full document
5
DDB1 Stimulates Viral Transcription of Hepatitis B Virus via HBx-Independent Mechanisms
... for viral DNA replica- tion, the extent to which the DDB1-HBx interaction contributes to HBx-stimulated viral DNA replication remained ...support viral DNA ...HBx-stimulated viral DNA ... See full document
10
Hepatitis B Virus Deregulates the Cell Cycle To Promote Viral Replication and a Premalignant Phenotype
... ABSTRACT Hepatitis B virus (HBV) infection is a major health problem worldwide, and chronically infected individuals are at high risk of developing cirrhosis and hep- atocellular carcinoma ... See full document
19
Inhibition of replication of hepatitis B virus using transcriptional repressors that target the viral DNA
... produce virus-targeting intermediates of the RNAi path- ...of viral sequences, which would lead to lasting inhibition of HBV ...of virus-targeting ... See full document
10
Hepatitis B virus infection
... Chronic hepatitis B virus infection affects about 400 million people around the globe and causes approximately a million deaths a ...of hepatitis B has evolved fast and the manage- ment ... See full document
144
Hepatitis B Virus Program
... Hepatitis B virus is a small, enveloped DNA virus that belongs to the family ...genotypes B and C are most common in China and Southeast ...hepatits B, it is the long-term ... See full document
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