[PDF] Top 20 Genes that regulate both development and longevity in Caenorhabditis elegans.

... Suppression of the Dafc phenotype by an epistatic daf-d mutation is defined as growth of at least twethirds of the experimental animals to adults (Table 1, values >6[r] ... See full document

... 11 genes that mutant, the ALM processes ended at or before the nerve affect touch cell ...for genes that regulate touch cell differentiation, more anteriorly than the eventual position of the ... See full document

... ABSTRACT Caenorhabditis elegans larval development requires the function of the two Canal-Associated Neurons (CANs): killing the CANs by laser microsurgery or disrupting their development by ... See full document

... tion group only if hermaphrodites of genotype a; b1/b2, Isolation of new synMuv strains: To identify new class where a is the background mutation required for the A mutations, we used EMS to mutagenize class B lin-36 ... See full document

... on Caenorhabditis elegans, Drosophila, Russell ...C. elegans have suggested ...to regulate the activity of the DAF-12 nuclear eren and De Vreese 1995) and caloric intake (Lakow- receptor ... See full document

... trans- genes harboring mutations on these SUMO acceptor sites of LIN-11 showed rescue of the vulval defects of lin-11 mutants, however, the UTSE was not normally ... See full document

... by both daf-2/IGFR mutations is fully suppressed by the null daf-16/FoxO allele mu86 (Lin et ...regulation. Both daf-16a mutations completely suppress the dauer- constitutive phenotype of daf-2(e1368) ... See full document

... tail development, respectively (see 1996), egl-20(⫹) is required for mab-5 expression in these cells ...bearing both the mutation and the mab-5::lacZ ... See full document

... carrying both unc-27 T gfp (bxEx97) and pkd-2 T gfp in an extrachromosomal array showed that non-Unc animals containing unc-27 T GFP-positive mus- cles and neurons had wild-type axon trajectories (N ¼ 106), ... See full document

... sequenced Caenorhabditis genomes each encode at least one HIL family member and they all contain a highly conserved ortholog of ...C. elegans, ...HIL genes. Of these, ehn-3 and R08E3.4 are ... See full document

... Genotypes were analyzed for the last-surviving 1-5% of worms in aging cohorts, and for young controls, by multiplex polymerase chain reaction using polymorphic marke[r] ... See full document

... Mutations in daf-2 and age-1 cause a dramatic increase in longevity as well as developmental arrest at the dauer diapause stage in Caenorhabditis elegans.. daf-2 and age-1 encode[r] ... See full document

... of genes upregulated in strain N2 after OrV infection (Data Set S1) and searched for associated motifs (E value of ⬍ ...C. elegans STA-1 and STA-2 and representative STATs from other organisms suggests that ... See full document

... the genes for axon guidance proteins, several motor proteins, vesicle components and autophagy-related ...UNC-14 regulate the subcellular localization of the Netrin receptor UNC-5, and that UNC-5 uses a ... See full document

... This raises the possibility that NDG, a hydrophobic compound, may interact with some types of ion channels directly, or indirectly, like a local anesthetic dissolved i[r] ... See full document

... of both GFP phenotype and Orsay virus RNA levels, the genes encode very different ...C. elegans orthologs (along with ...to regulate actin polymer- ization and the need for actin remodeling in ... See full document

... To identify genes that encode maternal components required for development of the germ line in the nematode Caenorhabditis elegans, we have screened for mutations t[r] ... See full document

... selected genes from ESPs data with a putative protease or protease inhibitor ...utse development, including shortened outgrowth of utse arms, incorrect migration of cell nuclei, were scored and recorded ... See full document

... Many C. elegans genes not found in D. coronatus were also absent from other non-Caenorhabditis species (Fig. 3). The peculiarities in early development of D. coronatus can thus not be ... See full document

... seven genes that affect the development of the Caenorhabditis elegans ...postembryonic development of the male-specific blast cells within the hindgut, the hindgut morphology in ... See full document