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[PDF] Top 20 The germ cell the mother of all stem cells

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The germ cell  the mother of all stem cells

The germ cell the mother of all stem cells

... adult an/an mice and their normal littermates were found to be present at birth, suggesting that this mutation affects PGC devel- opment. Subsequent analysis of PGC development in an/an em- bryos demonstrated that the ... See full document

8

STELLA Facilitates Differentiation of Germ Cell and Endodermal Lineages of Human Embryonic Stem Cells

STELLA Facilitates Differentiation of Germ Cell and Endodermal Lineages of Human Embryonic Stem Cells

... epiblast stem cells ...directed germ cell differentiation of human ES cells [11], and is co-expressed with VASA, a definitive germ cell marker, in germ cell ... See full document

8

A germ cell origin of embryonic stem cells?

A germ cell origin of embryonic stem cells?

... Embryonic stem (ES) cells are pluripotent (see Box 1) and can be expanded without limit in vitro (Evans and Kaufman, 1981; Martin, 1981; Thomson et ...pluripotent stem cell lines can be ... See full document

7

Retinoic acid enhances germ cell differentiation of mouse skin-derived stem cells

Retinoic acid enhances germ cell differentiation of mouse skin-derived stem cells

... ES cells into oocytes or sperm, though failed to show functioning gametes ...somatic stem cells, from pigs, mice and humans, have the ability to form primordial germ cell-like ... See full document

9

The role of stem cell factor and of alternative c kit gene products in the establishment, maintenance and function of germ cells

The role of stem cell factor and of alternative c kit gene products in the establishment, maintenance and function of germ cells

... mitotic cell cycle of dividing type A ...programmed cell death in cells which are intrinsically committed to proliferate (Packer et ...spermatogonial stem cells, ...the cell type ... See full document

10

The spermatogonial stem cell niche in testicular germ cell tumors

The spermatogonial stem cell niche in testicular germ cell tumors

... the cells to anaerobic ...many stem cell populations, including embryonic, hematopoietic, and neural stem cells among ...endothelial cells secrete paracrine factors that promote ... See full document

12

The migration and loss of human primordial germ stem cells from the hind gut epithelium towards the gonadal ridge

The migration and loss of human primordial germ stem cells from the hind gut epithelium towards the gonadal ridge

... primordial germ cells (PGCs) can be recognized in the yolk sac wall, from 3-4 weeks post conception (wpc), in the hind gut epithelium from week 4 and in the gonadal area from early week ...and stem ... See full document

9

Fish Stem Cell Cultures

Fish Stem Cell Cultures

... these germ cells into the PGC migratory route of developing trout and salmon embryos, thereby obtained germline chimeras that produced offspring from transplanted germ cells in a homologous ... See full document

11

Current protocols in the generation of pluripotent stem cells: theoretical, methodological and clinical considerations

Current protocols in the generation of pluripotent stem cells: theoretical, methodological and clinical considerations

... Pluripotent stem cells have been derived from various embryonic, fetal and adult ...Embryonic stem cells (ESCs) and parthenogenic ESCs (pESCs) are derived from the embryo proper while ... See full document

15

The control of sexual identity in the Drosophila germline

The control of sexual identity in the Drosophila germline

... that germ cells face along the way (see Box 1 for a discussion of ...a germ cell acquires a male versus female identity, but also how sexual identity influences other events, such as the ... See full document

9

Germ cells and germ cell transplantation

Germ cells and germ cell transplantation

... follicle cells, the mature oocyte can be fertilized and the resulting embryo transferred to the uterus, where it will develop to term, though the success rate is still very low (Eppig and O’Brien, ... See full document

6

Lipid phosphate phosphatase activity regulates dispersal and bilateral sorting of embryonic germ cells in Drosophila

Lipid phosphate phosphatase activity regulates dispersal and bilateral sorting of embryonic germ cells in Drosophila

... whether germ cell sorting into two gonads was a regulated process, we first analyzed the process in wild-type embryos with a genetic background where the number of germ cells was ...the ... See full document

9

VSELs may obviate cryobanking of gonadal tissue in cancer patients for fertility preservation

VSELs may obviate cryobanking of gonadal tissue in cancer patients for fertility preservation

... retains stem cells which can form germ cell ...of stem cells in adult ovary and we had argued that absence of evidence does not necessarily imply evidence for absence ...but ... See full document

8

RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche

RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche

... Stem cells are influenced by their surrounding microenvironment, or ...Sertoli cells are the key niche cells directing the population size and differentiation fate of spermatogonial ... See full document

11

In vitro Culture of Human Testicular Stem Cells on Feeder-Free Condition

In vitro Culture of Human Testicular Stem Cells on Feeder-Free Condition

... In the current study, we chose to examine the ex- pression of ubiquitin carboxyl-terminal esterase L1 (UCHL1); also known as protein gene product 9.5, because it is expressed in spermatogonia of many species including ... See full document

6

Targeted DamID reveals differential binding of mammalian pluripotency factors

Targeted DamID reveals differential binding of mammalian pluripotency factors

... homogeneous cells and antisera with high ...enable cell type-specific expression in mammalian systems, generating an inducible system (mammalian TaDa or MaTaDa) to identify genome-wide protein/DNA ... See full document

11

Stem cells of the reproductive tract of women

Stem cells of the reproductive tract of women

... into cells of the granulosa phe- notype in addition to epithelial, neural, and mesenchymal cell types, and when stimulated with estrogen, it differ- entiates directly into ...of germ cells ... See full document

7

Reinterpretation of evidence advanced for neo- oogenesis in mammals, in terms of a finite oocyte reserve

Reinterpretation of evidence advanced for neo- oogenesis in mammals, in terms of a finite oocyte reserve

... in germ cells, in the light of data presented [7,10], countermands the existence of neo-oogenesis and female germline stem ...germline stem cells in the ovary [7,12,15]; but section ... See full document

20

Expansion of Cord Blood Hematopoietic Stem Cells on the Amniotic Membrane Derived Mesenchymal Stem Cells

Expansion of Cord Blood Hematopoietic Stem Cells on the Amniotic Membrane Derived Mesenchymal Stem Cells

... hematopoietic stem cells (UCB-HSCs), expansion of these cells seems to be important for clinical application in ...mesenchymal stem cells (AMMSCs) as a feeder layer in order to expand ... See full document

9

Development of malignant germ cells   the genvironmental hypothesis

Development of malignant germ cells the genvironmental hypothesis

... of stem cells, ...between germ cells and their micro-environment, being under strict (interactive) control of genetic-, epigenetic-, and environmental parameters (Spradling et ... See full document

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